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Abd Al-Roof Higazi
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Journal Articles

Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability

Rami Abu-Fanne, Victoria Stepanova, Rustem I. Litvinov, Suhair Abdeen, Khalil Bdeir, Mohamed Higazi, Emad Maraga, Chandrasekaran Nagaswami, Alexander R. Mukhitov, John W. Weisel, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (2019) 133 (5): 481–493.
https://doi.org/10.1182/blood-2018-07-861237
Published: 2019
Includes: Supplemental data
Journal Articles

Endogenous plasminogen activators mediate progressive intracerebral hemorrhage after traumatic brain injury in mice

Nuha Hijazi, Rami Abu Fanne, Rinat Abramovitch, Serge Yarovoi, Muhamed Higazi, Suhair Abdeen, Maamon Basheer, Emad Maraga, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (2015) 125 (16): 2558–2567.
https://doi.org/10.1182/blood-2014-08-588442
Published: 2015
Includes: Supplemental data
Journal Articles

Contact with stroke

Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2012) 120 (19): 3870–3871.
https://doi.org/10.1182/blood-2012-09-455154
Published: 2012
Journal Articles

Nuclear translocation of urokinase-type plasminogen activator

Victoria Stepanova, Tatiana Lebedeva, Alice Kuo, Serge Yarovoi, Sergei Tkachuk, Sergei Zaitsev, Khalil Bdeir, Inna Dumler, Michael S. Marks, Yelena Parfyonova, Vsevolod A. Tkachuk, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2008) 112 (1): 100–110.
https://doi.org/10.1182/blood-2007-07-104455
Published: 2008
Includes: Multimedia, Supplemental data
Journal Articles

Regulation of the single-chain urokinase–urokinase receptor complex activity by plasminogen and fibrin: novel mechanism of fibrin specificity

Abd Al-Roof Higazi, Feras Ajawi, Sa'ed Akkawi, Edna Hess, Alice Kuo, Douglas B. Cines
Journal: Blood
Blood (2005) 105 (3): 1021–1028.
https://doi.org/10.1182/blood-2004-03-0995
Published: 2005
Journal Articles

In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone

Taher Nassar, Sa'ed Akkawi, Ahuva Shina, Abdullah Haj-Yehia, Khalil Bdeir, Mark Tarshis, Samuel N. Heyman, Abd Al-Roof Higazi
Journal: Blood
Blood (2004) 103 (3): 897–902.
https://doi.org/10.1182/blood-2003-05-1685
Published: 2004
Journal Articles

The kringle stabilizes urokinase binding to the urokinase receptor

Khalil Bdeir, Alice Kuo, Bruce S. Sachais, Ann H. Rux, Yasmina Bdeir, Andrew Mazar, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2003) 102 (10): 3600–3608.
https://doi.org/10.1182/blood-2003-03-0949
Published: 2003
Journal Articles

Human α-defensin regulates smooth muscle cell contraction: a role for low-density lipoprotein receptor–related protein/α 2 -macroglobulin receptor

Taher Nassar, Sa'ed Akkawi, Rachel Bar-Shavit, Abdullah Haj-Yehia, Khalil Bdeir, Abu-Bakr Al-Mehdi, Mark Tarshis, Abd Al-Roof Higazi
Journal: Blood
Blood (2002) 100 (12): 4026–4032.
https://doi.org/10.1182/blood-2002-04-1080
Published: 2002
Journal Articles

Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface

Bruce S. Sachais, Alice Kuo, Taher Nassar, Jeanelle Morgan, Katalin Kariko, Kevin Jon Williams, Michael Feldman, Michael Aviram, Neelima Shah, Leonard Jarett, Mortimer Poncz, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (2002) 99 (10): 3613–3622.
https://doi.org/10.1182/blood.V99.10.3613
Published: 2002
Journal Articles

Urokinase mediates fibrinolysis in the pulmonary microvasculature

Khalil Bdeir, Juan-Carlos Murciano, John Tomaszewski, Lauren Koniaris, Jose Martinez, Douglas B. Cines, Vladimir R. Muzykantov, Abd Al-Roof Higazi
Journal: Blood
Blood (2000) 96 (5): 1820–1826.
https://doi.org/10.1182/blood.V96.5.1820
Published: 2000
Journal Articles

The α-defensins stimulate proteoglycan-dependent catabolism of low-density lipoprotein by vascular cells: a new class of inflammatory apolipoprotein and a possible contributor to atherogenesis

Abd Al-Roof Higazi, Taher Nassar, Tomas Ganz, Daniel J. Rader, Raphael Udassin, Khalil Bdeir, Edna Hiss, Bruce S. Sachais, Kevin Jon Williams, Eran Leitersdorf, Douglas B. Cines
Journal: Blood
Blood (2000) 96 (4): 1393–1398.
https://doi.org/10.1182/blood.V96.4.1393
Published: 2000
Journal Articles

Defensin Promotes the Binding of Lipoprotein(a) to Vascular Matrix

Khalil Bdeir, William Cane, Gabriela Canziani, Irwin Chaiken, John Weisel, Marlys L. Koschinsky, Richard M. Lawn, Peter G. Bannerman, Bruce S. Sachais, Alice Kuo, Mark A. Hancock, John Tomaszewski, P.N. Raghunath, Tomas Ganz, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (1999) 94 (6): 2007–2019.
https://doi.org/10.1182/blood.V94.6.2007
Published: 1999
Journal Articles

Lysis of Plasma Clots by Urokinase-Soluble Urokinase Receptor Complexes

Abd Al-Roof Higazi, Khalil Bdeir, Edna Hiss, Shira Arad, Alice Kuo, Iyad Barghouti, Douglas B. Cines
Journal: Blood
Blood (1998) 92 (6): 2075–2083.
https://doi.org/10.1182/blood.V92.6.2075
Published: 1998
Journal Articles

Tissue Factor Regulates Plasminogen Binding and Activation

Zhiqiang Fan, Peter J. Larson, John Bognacki, P.N. Raghunath, John E. Tomaszewski, Alice Kuo, Gabriela Canziani, Irwin Chaiken, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (1998) 91 (6): 1987–1998.
https://doi.org/10.1182/blood.V91.6.1987
Published: 1998
Journal Articles

Defensin Stimulates the Binding of Lipoprotein (a) to Human Vascular Endothelial and Smooth Muscle Cells

Abd Al-Roof Higazi, Ehud Lavi, Khalil Bdeir, Anthony M. Ulrich, Dara G. Jamieson, Daniel J. Rader, David C. Usher, William Kane, Tomas Ganz, Douglas B. Cines
Journal: Blood
Blood (1997) 89 (12): 4290–4298.
https://doi.org/10.1182/blood.V89.12.4290
Published: 1997