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Marta Filizola
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Journal Articles

Cryo-Electron Microscopy Structure of the aIIbβ3-Abciximab Complex

Dragana Nesic, PhD, Yixiao Zhang, PhD, Aleksandar Spasic, PhD, Jihong Li, MD, Davide Provasi, PhD, Marta Filizola, PhD, Thomas Walz, PhD, Barry S. Coller, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3617.
https://doi.org/10.1182/blood-2019-126985
Published: 2019
Journal Articles

Development of a Pure Small Molecule αVβ3 Antagonist

Jihong Li, MD, Yoshiyuki Fukase, PhD, Yi Shang, PhD, Wei Zou, PhD, Ryoma Hara, PhD, Yuta Tanaka, PhD, Rei Okamoto, PhD, Takeshi Yasui, PhD, Takashi Nakahata, PhD, Toshihiro Imaeda, PhD, Kazuyoshi Aso, PhD, Charles Locuson, PhD, Dragana Nesic, PhD, Mark Duggan, PhD, Steven Teitelbaum, MD, Marta Filizola, PhD, Michael Foley, PhD, Barry S. Coller, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 548.
https://doi.org/10.1182/blood.V130.Suppl_1.548.548
Published: 2017
Journal Articles

Inhibiting SOX11-DNA Interaction in Mantle Cell Lymphoma

Stephanie Christie, Shashidhar Jatiani, PhD, Pei-Yu Kuo, MS, Violetta Leshchenko, PhD, Abhijeet Kapoor, PhD, Paola Bisignano, PhD, Aneel Aggarwal, PhD, Marta Filizola, PhD, Samir Parekh, MD
Journal: Blood
Blood (2016) 128 (22): 1840.
https://doi.org/10.1182/blood.V128.22.1840.1840
Published: 2016
Journal Articles

αIIbβ3 Variants Defined By Next Generation Sequencing: Implications for Predicting Variants Likely to Cause Glanzmann Thrombasthenia and Alloimmune Disorders

Claudia Lorena Buitrago, PhD#, Augusto Rendon, PhD#~, Ernest Turro, PhD, Yupu Liang, PhD, Ilenia Simeoni, PhD, Ana Negri, PhD, ThromboGenomics Consortium, Marta Filizola, PhD, Willem H. Ouwehand, MDPhDFRCPath FMedSci #, Barry S. Coller, MD#
Journal: Blood
Blood (2014) 124 (21): 4151.
https://doi.org/10.1182/blood.V124.21.4151.4151
Published: 2014
Journal Articles

Three-Dimensional Reconstruction of Intact Human Integrin α IIb β 3 in a Phospholipid Bilayer Nanodisc

Won-Seok Choi, PhD, Willam J. Rice, PhD, Ana Negri, PhD, Marta Filizola, PhD, David L. Stokes, PhD, Barry S. Coller, MD
Journal: Blood
Blood (2012) 120 (21): 92.
https://doi.org/10.1182/blood.V120.21.92.92
Published: 2012
Journal Articles

Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg 2+ From the β3 MIDAS,

Jieqing Zhu, PhD, Won-Seok Choi, PhD, Joshua G. McCoy, BS, MS, Ana Negri, PhD, Jianghai Zhu, PhD, Sarasija Naini, BS, MS, Jihong Li, MD, Min Shen, PhD, Wenwei Huang, PhD, Craig J. Thomas, PhD, Marta Filizola, PhD, Timothy Springer, PhD, Barry S. Coller, MD
Journal: Blood
Blood (2011) 118 (21): 3255.
https://doi.org/10.1182/blood.V118.21.3255.3255
Published: 2011
Journal Articles

Closed headpiece of integrin α IIb β 3 and its complex with an α IIb β 3 -specific antagonist that does not induce opening

Jieqing Zhu, Jianghai Zhu, Ana Negri, Davide Provasi, Marta Filizola, Barry S. Coller, Timothy A. Springer
Journal: Blood
Blood (2010) 116 (23): 5050–5059.
https://doi.org/10.1182/blood-2010-04-281154
Published: 2010
Includes: Supplemental data
Journal Articles

Structural, Functional, and Dynamic Characterization of the Binding Site of RUC-1, a Novel αIIb-Specific Inhibitor of Integrin αIIbβ3.

Jieqing Zhu, PhD, Jianghai Zhu, PhD, Ana Negri, PhD, Davide Provasi, PhD, Marta Filizola, PhD, Barry S. Coller, MD, Timothy A Springer, PhD
Journal: Blood
Blood (2009) 114 (22): 151.
https://doi.org/10.1182/blood.V114.22.151.151
Published: 2009
Journal Articles

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist

Robert Blue, M. Anna Kowalska, Jessica Hirsch, Marta Murcia, Christin A. Janczak, Amanda Harrington, Marketa Jirouskova, Jihong Li, Rudy Fuentes, Michael A. Thornton, Marta Filizola, Mortimer Poncz, Barry S. Coller
Journal: Blood
Blood (2009) 114 (1): 195–201.
https://doi.org/10.1182/blood-2008-08-169243
Published: 2009
Includes: Multimedia, Supplemental data
Journal Articles

Structural and Therapeutic Insights from the Species Specificity and in Vivo Antithrombotic Activity of a Novel αIIb-Specific αIIbβ3 Antagonist

Robert Blue, M. Anna Kowalska, PhD, Marta Murcia, PhD, Christin A. Janczak, Marketa Jirouskova, PhD, Jihong Li, MD, Amanda Harrington, Rudy Fuentes, Michael A. Thornton, PhD, Marta Filizola, Mortimer Poncz, MD, Barry S. Coller, MD
Journal: Blood
Blood (2008) 112 (11): 256.
https://doi.org/10.1182/blood.V112.11.256.256
Published: 2008
Journal Articles

Limiting αIIb Extension at the Genu Differentially Affects Binding of Small and Large Ligands to αIIbβ3

Robert Blue, Jonathan Steinberger, MD, Jihong Li, MD, Marta Murcia, PhD, Marta Filizola, Barry S. Coller, MD
Journal: Blood
Blood (2008) 112 (11): 255.
https://doi.org/10.1182/blood.V112.11.255.255
Published: 2008
Journal Articles

Functional and Computational Analysis of the Role of the Adjacent to Metal Ion-Dependent Adhesion Site (ADMIDAS) of Integrin αIIbβ3.

Marketa Jirouskova, PhD, Marta Murcia, PhD, JiHong Li, MD, Marta Filizola, PhD, Barry S. Coller, MD
Journal: Blood
Blood (2006) 108 (11): 143.
https://doi.org/10.1182/blood.V108.11.143.143
Published: 2006