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Journal Articles

Glucose transporter 5 enhances CAR-T cell metabolic function and serial killing

Free
Bakir Valentic, Andre Kelly, Feng Shen, John Scholler, Max Shestov, Nathaniel Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy O'Connor
Journal: Blood
Blood (2025) 146 (Supplement 1): 2351.
https://doi.org/10.1182/blood-2025-2351
Published: 2025
Journal Articles

Lipid nanoparticle-mediated epitope editing in human HSPCs enables resistance to CD45-directed CAR-T cell therapy

Free
Chenchen Li, Vilas Desai, Elahe Kamali Ghahe, Davin Tafuri, Rujul Jagdish Deolikar, Natalie Cooper, Nils Wellhausen, Feng Shen, Reka Geczy, Aruna Balgi, Samuel Clarke, Jennifer Moody, Anne Chew, Carl June, Saar Gill, Friederike Herbst
Journal: Blood
Blood (2025) 146 (Supplement 1): 1048.
https://doi.org/10.1182/blood-2025-1048
Published: 2025
Journal Articles

Single-day non-activated IL-18-armed CAR T cells with enhanced persistence and durable efficacy

Free
Joseph Durgin, Shin Seo, Shadab Kazmi, Bakir Valentic, Chloe Leff, Xioling Jin, Feng Shen, Nandana Mukherjee, Ashwin Sannecy, Gabriela Plesa, Khatuna Gabunia, John Scholler, Saar Gill, Roddy O'Connor, Carl June, Saba Ghassemi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4187.
https://doi.org/10.1182/blood-2025-4187
Published: 2025
Journal Articles

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 Enhances Anti-Tumor Activity and Obviates the Need for Lymphodepletion in Non-Human Primates

Free
Sara Sleiman, Tyler Hansen, Nathan D Mathewson, Feng Shen, Miroslaw Kozlowski, Olga Shestova, Maksim Shestov, Danuta Jarocha, Vanessa Gonzalez, Joseph A. Fraietta, Hannah Thomas, Jack Swain, Raimon Duran-Struuck, Kelly D. Moynihan, Paul Bessette, Chris Kimberlin, Meghana Sukthankar, Terrence Park, Andy Yeung, Ivana Djuretic, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 499.
https://doi.org/10.1182/blood-2024-198249
Published: 2024
Journal Articles

BTK Inhibition Prevents the Induction of Myeloid-Derived Suppressor Cells in Malignancy and Improves CART Function

Free
Benjamin F. Frost, Olga Shestova, Sara Sleiman, Brandon Simone, Feng Shen, Miroslaw Kozlowski, Michelle Wang, J. Joseph Melenhorst, Noelle Frey, Elizabeth O. Hexner, Megan M. Davis, Joseph A. Fraietta, Avery Gaymon, Rong Xu, Chia Sharpe, John C. Byrd, Mark O'Hara, Adam D. Cohen, Stephen J. Schuster, Donald L. Seigel, Carl H. June, David L. Porter, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 909.
https://doi.org/10.1182/blood-2024-202659
Published: 2024
Journal Articles

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 or IL-21 Cytokines Results in Enhanced Anti-Tumor Activity

Free
Sara Sleiman, Nathan D Mathewson, Feng Shen, Kelly Moynihan, Wei Chen, Paul Bessette, Chris Kimberlin, Danielle Pappas, Terrence Park, Andy Yeung, Ivana Djuretic, Saar Gill
Journal: Blood
Blood (2022) 140 (Supplement 1): 10259–10260.
https://doi.org/10.1182/blood-2022-168411
Published: 2022
Journal Articles

Enhanced Efficacy of the SYK Inhibitor Entospletinib and Chemotherapy in Infant Acute Lymphoblastic Leukemia

Free
Joseph Patrick Loftus, BS, Anella Yahiaoui, BS, Feng Shen, MDPhD, David Lopez, Igor Mikaelian, DVM, Patrick A Brown, MD, Stacey Tannheimer, PhD, Ann Forslund, PhD, Sarah K Tasian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2611.
https://doi.org/10.1182/blood.V130.Suppl_1.2611.2611
Published: 2017
Journal Articles

Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia

Free
Sarah K. Tasian, Saad S. Kenderian, Feng Shen, Marco Ruella, Olga Shestova, Miroslaw Kozlowski, Yong Li, April Schrank-Hacker, Jennifer J. D. Morrissette, Martin Carroll, Carl H. June, Stephan A. Grupp, Saar Gill
Journal: Blood
Blood (2017) 129 (17): 2395–2407.
https://doi.org/10.1182/blood-2016-08-736041
Published: 2017
Includes: Supplemental data
Journal Articles

Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia

Free
Sarah K. Tasian, David T. Teachey, Yong Li, Feng Shen, Richard C. Harvey, I-Ming Chen, Theresa Ryan, Tiffaney L. Vincent, Cheryl L. Willman, Alexander E. Perl, Stephen P. Hunger, Mignon L. Loh, Martin Carroll, Stephan A. Grupp
Journal: Blood
Blood (2017) 129 (2): 177–187.
https://doi.org/10.1182/blood-2016-05-707653
Published: 2017
Includes: Supplemental data
Journal Articles

Preclinical Development of FLT3-Redirected Chimeric Antigen Receptor T Cell Immunotherapy for Acute Myeloid Leukemia

Free
Christopher Daniel Chien, PhD, Christopher Tor Sauter, BA, Kazusa Ishii, MD MPH, Sang Minh Nguyen, BS, Feng Shen, MD PhD, Sarah K Tasian, MD, Weizao Chen, PhD, Dimiter S Dimitrov, PhD, Terry J Fry, MD
Journal: Blood
Blood (2016) 128 (22): 1072.
https://doi.org/10.1182/blood.V128.22.1072.1072
Published: 2016
Journal Articles

Evaluating on-Target Toxicity of Hematopoietic-Targeting Cars Demonstrates Target-Nonspecific Suppression of Marrow Progenitors

Free
Christopher Tor Sauter, BA, Christopher Daniel Chien, PhD, Feng Shen, MD PhD, Sarah K Tasian, MD, Terry J Fry, MD
Journal: Blood
Blood (2016) 128 (22): 3357.
https://doi.org/10.1182/blood.V128.22.3357.3357
Published: 2016
Journal Articles

Efficient Termination of CD123-Redirected Chimeric Antigen Receptor T Cells for Acute Myeloid Leukemia to Mitigate Toxicity

Free
Sarah K Tasian, MD, Saad S Kenderian, MD, Feng Shen, MDPhD, Yong Li, MDMS, Marco Ruella, MD, William C Fix, BA, Miroslaw Kozlowski, PhD, Martin Carroll, MD, Richard Aplenc, MD PhD, Carl H June, MD, Stephan A Grupp, MD PhD, Saar I Gill, MBBS, PhD
Journal: Blood
Blood (2015) 126 (23): 565.
https://doi.org/10.1182/blood.V126.23.565.565
Published: 2015
Journal Articles

Potent Efficacy of Combined PI3K/mTOR and JAK or SRC/ABL Inhibition in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia

Free
Sarah K Tasian, MD, Yong Li, MDMS, Feng Shen, MDPhD, Theresa Ryan, Tiffaney L Vincent, David T Teachey, MD, Shannon L Maude, MD PhD, Richard C Harvey, PhD, I-Ming L Chen, DVM, MS, Cheryl L Willman, Alexander E. Perl, MD, Stephen P Hunger, MD, Mignon L. Loh, MD, Martin Carroll, MD, Stephan A. Grupp, MD PhD
Journal: Blood
Blood (2015) 126 (23): 798.
https://doi.org/10.1182/blood.V126.23.798.798
Published: 2015
Journal Articles

Continuous intravenous injection of Mesna can effectively prevent Hemorrhagic cystitis in hematopoietic stem cell transplantation and retain the Mesna's concentration in urine: 394 cases reported within 11 years

Free
Qianli Jiang, MD PhD, Hao Huang, MD, Qifa Liu, MD, Jing Sun, MD, Hongsheng Zhou, MD, Zhiping Fan, Yu Zhang, Fen Huang, Yanyan Chai, MD, Dan Xu, Qiusui Mai, Qi Wei, PhDMD, Guo-Pan Yu, MD, Xiaofang Li, PhD, Min Dai, PhD, Na Xu, Dandan Zhou, Haiyun Zhao, Ke feng Shen, Yongjun Zhou, MD, Fanyi Meng
Journal: Blood
Blood (2014) 124 (21): 2483.
https://doi.org/10.1182/blood.V124.21.2483.2483
Published: 2014
Journal Articles

Essential roles for Pot1b in HSC self-renewal and survival

Free
Yang Wang, Mei-Feng Shen, Sandy Chang
Journal: Blood
Blood (2011) 118 (23): 6068–6077.
https://doi.org/10.1182/blood-2011-06-361527
Published: 2011
Includes: Supplemental data
Journal Articles

Microfluidic Tools To Probe the Spatial Dynamics of Coagulation.

Free
Christian J. Kastrup, MS, Matthew K. Runyon, M.S., Feng Shen, M.S., Rustem F. Ismagilov, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3934.
https://doi.org/10.1182/blood.V110.11.3934.3934
Published: 2007