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Journal Articles

Lipid nanoparticle-mediated epitope editing in human HSPCs enables resistance to CD45-directed CAR-T cell therapy

Chenchen Li, Vilas Desai, Elahe Kamali Ghahe, Davin Tafuri, Rujul Jagdish Deolikar, Natalie Cooper, Nils Wellhausen, Feng Shen, Reka Geczy, Aruna Balgi, Samuel Clarke, Jennifer Moody, Anne Chew, Carl June, Saar Gill, Friederike Herbst

Blood (2025) 146 (Supplement 1): 1048.

https://doi.org/10.1182/blood-2025-1048

Published: 2025

Journal Articles

Expansion of human hematopoietic stem cells by inhibiting translation

Chenchen Li, Hanna Shin, Dheeraj Bhavanasi, Xiaolei Liu, Mai Liu, Yu Xiang, Scott Peslak, Friederike Herbst, Mohamad-Gabriel Alameh, Laura Breda, Stefano Rivella, Juan Alvarez-Dominguez, Gerd Blobel, Brian Gregory, Jian Huang, Peter Klein

Blood (2025) 146 (Supplement 1): 1379.

https://doi.org/10.1182/blood-2025-1379

Published: 2025

Journal Articles

Toward ‘n of one’ gene therapies: Scalable ex vivo adenine base editing via lipid nanoparticles in a sickle cell disease model

Sarah Cotteta, Omar Banda, Friederike Herbst-Nowrouzi, Brooklyn McDonald, Yongping Wang, Mohamad-Gabriel Alameh, Frederic Bushman, Stephan Grupp, Eugene Khandros, Stephan Kadauke

Blood (2025) 146 (Supplement 1): 7835.

https://doi.org/10.1182/blood-2025-7835

Published: 2025

Journal Articles

Identification and Validation of Novel Hematopoietic Stem Cell Regulatory microRNAs

Elias Simon Peter Eckert, Peer Wünsche, Manfred Schmidt, PhD, Claudia Ball, PhD, Friederike Herbst, PhD, Hanno Glimm

Blood (2016) 128 (22): 3872.

https://doi.org/10.1182/blood.V128.22.3872.3872

Published: 2016

Journal Articles

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Isabell Schulze, Christian Rohde, Marina Scheller-Wendorff, Nicole Bäumer, Annika Krause, Friederike Herbst, Pia Riemke, Katja Hebestreit, Petra Tschanter, Qiong Lin, Heinz Linhart, Lucy A. Godley, Hanno Glimm, Martin Dugas, Wolfgang Wagner, Wolfgang E. Berdel, Frank Rosenbauer, Carsten Müller-Tidow

Blood (2016) 127 (12): 1575–1586.

https://doi.org/10.1182/blood-2015-07-655928

Published: 2016

Includes: Supplemental data

Journal Articles

The Common Genomic Locus of Evl and MiR-342 Regulates Both Lymphopoiesis and Myelopoiesis

Tonio Lang, Friederike Herbst, PhD, Elias Eckert, Peer Wünsche, Shayda Hemmati, PhD, Tim Kindinger, Nina Hofmann, Oksana Zavidij, PhD, Manfred Schmidt, PhD, Claudia Ball, PhD, Hanno Glimm, MD

Blood (2015) 126 (23): 2366.

https://doi.org/10.1182/blood.V126.23.2366.2366

Published: 2015

Journal Articles

Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.

Friederike Herbst, PhD, Claudia R Ball, PhD, Oksana Zavidij, PhD, Annika Mengering, Sylvia Fessler, Manfred Schmidt, PhD, Christof von Kalle, MD, PhD, Hanno Glimm, MD

Blood (2012) 120 (21): 2398.

https://doi.org/10.1182/blood.V120.21.2398.2398

Published: 2012

Journal Articles

Deregulated EVI1 Expression Leads to Genomic Instability and G1 Cell Cycle Arrest

Friederike Herbst, Claudia R Ball, PhD, Wei Wang, Kadin Karakaya, Sylvia Fessler, Alwin Krämer, MD, Manfred Schmidt, PhD, Christof von Kalle, MD, Hanno Glimm, MD

Blood (2011) 118 (21): 2431.

https://doi.org/10.1182/blood.V118.21.2431.2431

Published: 2011

Journal Articles

Impaired Lentiviral Transgene Expression In Vivo Caused by Massive Methylation of SFFV Promoter Sequences.

Friederike Herbst, Claudia R Ball, PhD, Francesca Tuorto, PhD, Wei Wang, Ulrich Kloz, Frank van der Hoeven, Frank Lyko, PhD, Christof Von Kalle, MD, Hanno Glimm, MD

Blood (2010) 116 (21): 3760.

https://doi.org/10.1182/blood.V116.21.3760.3760

Published: 2010

Journal Articles

Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation

Oksana Zavidij, Claudia R. Ball, Friederike Herbst, Sylvia Fessler, Manfred Schmidt, Christof von Kalle, Hanno Glimm

Blood (2010) 115 (24): 5023–5025.

https://doi.org/10.1182/blood-2010-02-271528

Published: 2010

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Lipid nanoparticle-mediated epitope editing in human HSPCs enables resistance to CD45-directed CAR-T cell therapy

Expansion of human hematopoietic stem cells by inhibiting translation

Toward ‘n of one’ gene therapies: Scalable ex vivo adenine base editing via lipid nanoparticles in a sickle cell disease model

Identification and Validation of Novel Hematopoietic Stem Cell Regulatory microRNAs

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

The Common Genomic Locus of Evl and MiR-342 Regulates Both Lymphopoiesis and Myelopoiesis

Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.

Deregulated EVI1 Expression Leads to Genomic Instability and G1 Cell Cycle Arrest

Impaired Lentiviral Transgene Expression In Vivo Caused by Massive Methylation of SFFV Promoter Sequences.

Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation

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