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Journal Articles

Clinical Benefit Associated with Biomarker Changes Indicative of Disease Modification in Patients with Myelofibrosis Treated with the BET Inhibitor Pelabresib As Monotherapy or in Combination with Ruxolitinib

Joseph Scandura, Srdan Verstovsek, Marina Kremyanskaya, Moshe Talpaz, Raajit K Rampal, Alessandro Vannucchi, Vikas Gupta, Francesca Palandri, Andrea Patriarca, Prithviraj Bose, Dong Chen, Oksana Zavidij, Jike Cui, Tzuu-Wang Chang, Pietro Taverna, John Mascarenhas, Claire Harrison

Blood (2022) 140 (Supplement 1): 1523–1525.

https://doi.org/10.1182/blood-2022-159409

Published: 2022

Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Progression in Patients with High-Risk Smoldering Multiple Myeloma Treated with Immunotherapy

Romanos Sklavenitis-Pistofidis, Michelle P. Aranha, Nicholas J. Haradhvala, Shohreh Varmeh, Daniel Heilpern-Mallory, Ting Wu, Nang Kham Su, Elizabeth D. Lightbody, François Aguet, Oksana Zavidij, Sabrin Tahri, Tarek H. Mouhieddine, Gad Getz, Irene Ghobrial

Blood (2022) 140 (Supplement 1): 268–269.

https://doi.org/10.1182/blood-2022-168839

Published: 2022

Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Response to Immunotherapy in Patients with High-Risk Smoldering Myeloma

Blood (2021) 138 (Supplement 1): 330.

https://doi.org/10.1182/blood-2021-147623

Published: 2021

Journal Articles

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Blood (2021) 138 (Supplement 1): 2568.

https://doi.org/10.1182/blood-2021-152267

Published: 2021

Journal Articles

Single Cell Characterization of Myeloma and Its Precursor Conditions Reveals Transcriptional Signatures of Early Tumorigenesis

Rebecca Boiarsky, Nicholas Haradhvala, Romanos Sklavenitis-Pistofidis, Tarek H Mouhieddine, Jean-Baptiste Alberge, Oksana Zavidij, Danielle Firer, Shankara Anand, Habib El-Khoury, François Aguet, David Sontag, Irene M. Ghobrial, Gad Getz

Blood (2021) 138 (Supplement 1): 2219.

https://doi.org/10.1182/blood-2021-150889

Published: 2021

Journal Articles

The BET Inhibitor, CPI-0610, Promotes Myeloid Differentiation in Myelofibrosis Patient Bone Marrow and Peripheral CD34+ Hematopoietic Stem Cells

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-138752

Published: 2020

Journal Articles

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients

Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Chia-Jen Liu, Mairead Reidy, Oksana Zavidij, Daisy Huynh, Patrick Henrick, Alexandra Savell, Kaitlen Reyes, Bradley Rivotto, Mark Bustoros, Adriana Perilla-Glen, Lorenzo Trippa, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial

Blood (2018) 132 (24): 2608–2612.

https://doi.org/10.1182/blood-2018-07-863241

Published: 2018

Journal Articles

Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Chia-jen Liu, MD, Irene M. Ghobrial, MD, Mark Bustoros, MD, Kaitlen Reyes, NP, Kalvis Hornburg, BA, Ashraf Z. Badros, MD, James J. Vredenburgh, MD, Adam Boruchov, MD, Jeffrey V Matous, MD, Aaron Caola, BS, Bradley Rivotto, BS, Alexandra Savell, BS, Patrick Henrick, BS, Claudia E. Paba-Prada, MD, Robert L. Schlossman, MD, Jacob Laubach, MD, Jacalyn Rosenblatt, MD, Andrew J Yee, MD, Omar Nadeem, MD, Rodrigo O. Maegawa, MD, Andrzej Jakubowiak, MD PhD, Saad Z. Usmani, MD, Manisha Bhutani, MD, Joseph Cappuccio, BS, Brianna Berrios, BS, Kimberly Noonan, NP, Oksana Zavidij, PhD, Tarek H Mouhieddine, MD, Cody J Boehner, Carl-Jannes Neuse, Karma Ziad Salem, MD, Mairead Reidy, PhD, Jihye Park, PhD, Michael Agius, PhD, Mahshid Rahmat, PhD, Salomon Manier, MD PhD, Divaya Bhutani, MD, Jeffrey A Zonder, MD, Nikhil Munshi, MD, Daniel Auclair, PhD, Kenneth Anderson, MD, Paul Richardson

Blood (2018) 132 (Supplement 1): 154.

https://doi.org/10.1182/blood-2018-154

Published: 2018

Journal Articles

Single-Cell RNA Sequencing Reveals Compromised Immune Microenvironment in Precursor Stages of Multiple Myeloma

Blood (2018) 132 (Supplement 1): 2603.

https://doi.org/10.1182/blood-2018-99-114145

Published: 2018

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

Yujia Shen, PhD, Salomon Manier, MD PhD, Sabrin Tahri, MD, Brianna Berrios, BS, Oksana Zavidij, PhD, Jihye Park, PhD, Romanos Pistofidis, MD, Irene M. Ghobrial, MD

Blood (2018) 132 (Supplement 1): 57.

https://doi.org/10.1182/blood-2018-99-113842

Published: 2018

Journal Articles

A Rationally Designed Novel Polymer for Safe and Synergistic Delivery of High Dose Bortezomib, Pomalidomide/Lenalidomide, and Dexamethasone for Multiple Myeloma

Alexandre Detappe, PhD, Hung Nguyen, Clelia Mathieu, MSc, Yivan Jiang, PhD, Michael Agius, PhD, Oksana Zavidij, PhD, Brianna Berrios, BS, Yujia Shen, PhD, Jeremiah A Johnson, PhD, Paiman Peter Ghoroghchian, MD PhD, Irene M. Ghobrial, MD

Blood (2018) 132 (Supplement 1): 4681.

https://doi.org/10.1182/blood-2018-99-116517

Published: 2018

Journal Articles

Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis

Antonio Sacco, BS, Yawara Kawano, MD PhD, Michele Moschetta, MD, Jihye Park, PhD, Oksana Zavidij, PhD, Michaela Reagan, PhD, Yuji Mishima, PhD, Elizabeth A. Morgan, MD, Satoshi Takagi, PhD, Salomon Manier, MD, Luisa Imberti, MD, Giuseppe Rossi, MD, Kwok Wong, MD, Ruben D. Carrasco, MD PhD, Irene M. Ghobrial, MD, Aldo M. Roccaro, MD PhD

Blood (2016) 128 (22): 4169.

https://doi.org/10.1182/blood.V128.22.4169.4169

Published: 2016

Journal Articles

Microrna-138 Regulates Osteogenic Differentiation and Its Inhibition Presents a Novel Therapeutic Line to Prevent Bone Lytic Lesions in Multiple Myeloma

Shokichi Tsukamoto, MD PhD, Karma Salem, MD, Salomon Manier, MD, Michaela R. Reagan, PhD, Daisy Huynh, BS, MS, Adriana Perilla-Glen, MBA, Antonio Sacco, BS, Oksana Zavidij, PhD, Mahshid Rahmat, PhD, Satoshi Takagi, PhD, Yawara Kawano, MD PhD, Katsutoshi Kokubun, PhD, Charlotte Albæk Thrue, MSc, Andreas Petri, PhD MSc, David M. Dorfman, MD PhD, Aldo M. Roccaro, MD PhD, Marzia Capelletti, PhD MMSc, Sakari Kauppinen, PhD, Irene M. Ghobrial, MD

Blood (2016) 128 (22): 4483.

https://doi.org/10.1182/blood.V128.22.4483.4483

Published: 2016

Journal Articles

The Common Genomic Locus of Evl and MiR-342 Regulates Both Lymphopoiesis and Myelopoiesis

Tonio Lang, Friederike Herbst, PhD, Elias Eckert, Peer Wünsche, Shayda Hemmati, PhD, Tim Kindinger, Nina Hofmann, Oksana Zavidij, PhD, Manfred Schmidt, PhD, Claudia Ball, PhD, Hanno Glimm, MD

Blood (2015) 126 (23): 2366.

https://doi.org/10.1182/blood.V126.23.2366.2366

Published: 2015

Journal Articles

Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.

Friederike Herbst, PhD, Claudia R Ball, PhD, Oksana Zavidij, PhD, Annika Mengering, Sylvia Fessler, Manfred Schmidt, PhD, Christof von Kalle, MD, PhD, Hanno Glimm, MD

Blood (2012) 120 (21): 2398.

https://doi.org/10.1182/blood.V120.21.2398.2398

Published: 2012

Journal Articles

Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation

Oksana Zavidij, Claudia R. Ball, Friederike Herbst, Sylvia Fessler, Manfred Schmidt, Christof von Kalle, Hanno Glimm

Blood (2010) 115 (24): 5023–5025.

https://doi.org/10.1182/blood-2010-02-271528

Published: 2010

Journal Articles

In Vivo Lentiviral Marking Demonstrates Long-Term Myeloid and Lymphoid Lineage Contribution of Individual Hematopoietic Stem Cell Clones to Murine Steady-State Hematopoiesis.

Oksana Zavidij, Claudia R Ball, Sylvia Fessler, Daniela Belle, Manfred Schmidt, Christof von Kalle, MD, Hanno Glimm, MD

Blood (2009) 114 (22): 813.

https://doi.org/10.1182/blood.V114.22.813.813

Published: 2009

Journal Articles

Hematopoietic Activity of Human Short Term Repopulating Cells in Mobilized Peripheral Blood Cell Transplants Is Restricted to the First 5Months after Transplantation.

Oksana Zavidij, Claudia R Ball, PhD, Sylvia Fessler, Manfred Schmidt, PhD, Christof von Kalle, MD, Hanno Glimm, MD

Blood (2008) 112 (11): 1386.

https://doi.org/10.1182/blood.V112.11.1386.1386

Published: 2008

NARROW

Clinical Benefit Associated with Biomarker Changes Indicative of Disease Modification in Patients with Myelofibrosis Treated with the BET Inhibitor Pelabresib As Monotherapy or in Combination with Ruxolitinib

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Progression in Patients with High-Risk Smoldering Multiple Myeloma Treated with Immunotherapy

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Response to Immunotherapy in Patients with High-Risk Smoldering Myeloma

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Single Cell Characterization of Myeloma and Its Precursor Conditions Reveals Transcriptional Signatures of Early Tumorigenesis

The BET Inhibitor, CPI-0610, Promotes Myeloid Differentiation in Myelofibrosis Patient Bone Marrow and Peripheral CD34+ Hematopoietic Stem Cells

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients

Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Single-Cell RNA Sequencing Reveals Compromised Immune Microenvironment in Precursor Stages of Multiple Myeloma

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma

A Rationally Designed Novel Polymer for Safe and Synergistic Delivery of High Dose Bortezomib, Pomalidomide/Lenalidomide, and Dexamethasone for Multiple Myeloma

Dual Conditional Loss of BLIMP-1 and p53 in B-Cells Drives B-Cell Lymphomagenesis

Microrna-138 Regulates Osteogenic Differentiation and Its Inhibition Presents a Novel Therapeutic Line to Prevent Bone Lytic Lesions in Multiple Myeloma

The Common Genomic Locus of Evl and MiR-342 Regulates Both Lymphopoiesis and Myelopoiesis

Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.

Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation

In Vivo Lentiviral Marking Demonstrates Long-Term Myeloid and Lymphoid Lineage Contribution of Individual Hematopoietic Stem Cell Clones to Murine Steady-State Hematopoiesis.

Hematopoietic Activity of Human Short Term Repopulating Cells in Mobilized Peripheral Blood Cell Transplants Is Restricted to the First 5Months after Transplantation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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