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Journal Articles

MYC Overexpressing Multiple Myeloma Are Dependent on GLS1

Katarina K Jovanovic, PhD, Léa Fléchon, MSc, Mairead Reidy, PhD, Jihye Park, BS, DVM, Xavier Leleu, MD PhD, Irene M. Ghobrial, MD, Thierry Facon, MD, Bruno Quesnel, Salomon Manier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 853.
https://doi.org/10.1182/blood-2019-128484
Published: 2019
Journal Articles

A High-Throughput Drug Screen Reveals a Novel Compound Class That Significantly Depletes IRF4 Expression in Multiple Myeloma

Elizabeth D. Lightbody, PhD, Mairead Reidy, PhD, Michael P. Agius, PhD, Salma El-Behaedi, BSc, Romanos Sklavenitis-Pistofidis, MD, Salomon Manier, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5545.
https://doi.org/10.1182/blood-2019-130910
Published: 2019
Journal Articles

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients

Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Chia-Jen Liu, Mairead Reidy, Oksana Zavidij, Daisy Huynh, Patrick Henrick, Alexandra Savell, Kaitlen Reyes, Bradley Rivotto, Mark Bustoros, Adriana Perilla-Glen, Lorenzo Trippa, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial
Journal: Blood
Blood (2018) 132 (24): 2608–2612.
https://doi.org/10.1182/blood-2018-07-863241
Published: 2018
Journal Articles

Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Chia-jen Liu, MD, Irene M. Ghobrial, MD, Mark Bustoros, MD, Kaitlen Reyes, NP, Kalvis Hornburg, BA, Ashraf Z. Badros, MD, James J. Vredenburgh, MD, Adam Boruchov, MD, Jeffrey V Matous, MD, Aaron Caola, BS, Bradley Rivotto, BS, Alexandra Savell, BS, Patrick Henrick, BS, Claudia E. Paba-Prada, MD, Robert L. Schlossman, MD, Jacob Laubach, MD, Jacalyn Rosenblatt, MD, Andrew J Yee, MD, Omar Nadeem, MD, Rodrigo O. Maegawa, MD, Andrzej Jakubowiak, MD PhD, Saad Z. Usmani, MD, Manisha Bhutani, MD, Joseph Cappuccio, BS, Brianna Berrios, BS, Kimberly Noonan, NP, Oksana Zavidij, PhD, Tarek H Mouhieddine, MD, Cody J Boehner, Carl-Jannes Neuse, Karma Ziad Salem, MD, Mairead Reidy, PhD, Jihye Park, PhD, Michael Agius, PhD, Mahshid Rahmat, PhD, Salomon Manier, MD PhD, Divaya Bhutani, MD, Jeffrey A Zonder, MD, Nikhil Munshi, MD, Daniel Auclair, PhD, Kenneth Anderson, MD, Paul Richardson
Journal: Blood
Blood (2018) 132 (Supplement 1): 154.
https://doi.org/10.1182/blood-2018-154
Published: 2018
Journal Articles

Dissecting the Epigenetic Landscape of Smoldering, Newly Diagnosed and Relapsed Multiple Myeloma Revealed IRAK3 As a Marker of Disease Progression

Mahshid Rahmat, PhD, Nicholas Haradhvala, BA, Romanos Sklavenitis-Pistofidis, MD, Jihye Park, PhD, Daisy Huynh, MS, Mark Bustoros, MD, Brianna Berrios, BS, Mairead Reidy, PhD, Adriana Perilla-Glen, Bradley Rivotto, BS, Kalvis Hornburg, BA, David M. Dorfman, MD, PhD, Jonathan D. Licht, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3896.
https://doi.org/10.1182/blood-2018-99-115046
Published: 2018
Journal Articles

Single-Cell RNA Sequencing Reveals Compromised Immune Microenvironment in Precursor Stages of Multiple Myeloma

Oksana Zavidij, PhD, Nicholas Haradhvala, BA, Tarek H Mouhieddine, MD, Jihye Park, PhD, Romanos Pistofidis, MD, Mairead Reidy, PhD, Daisy Huynh, MS, Marzia Capelletti, PhD, Brianna Berrios, BS, Mahshid Rahmat, PhD, Mark Bustoros, MD, Chia-Jen Liu, MD, Meng Xiao He, AB, Yosef Maruvka, PhD, Bradley Rivotto, BS, Kalvis Hornburg, BA, Melissa Goldman, PhD, Eliezer Van Allen, MD, Steven A McCarroll, PhD, Jamil Azzi, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2603.
https://doi.org/10.1182/blood-2018-99-114145
Published: 2018
Journal Articles

Founding Precision Therapy in 1q-Amplified Multiple Myeloma

Romanos Sklavenitis-Pistofidis, MD, Mairead Reidy, PhD, Daisy Huynh, MS, Karma Ziad Salem, MD, Jihye Park, PhD, Siobhan Glavey, MD PhD, Xavier Leleu, MD PhD, David Root, PhD, Irene M. Ghobrial, MD, Salomon Manier, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1007.
https://doi.org/10.1182/blood-2018-99-112673
Published: 2018
Journal Articles

Development of an Antibody-Targeted Nanoparticle for Early Detection of Minimal Residual Disease in Multiple Myeloma

Alexandre Detappe, PhD, Mairead Reidy, PhD, Peter P Ghoroghchian, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4430.
https://doi.org/10.1182/blood.V130.Suppl_1.4430.4430
Published: 2017
Journal Articles

The Dual PIM/PI3-K Inhibitor Ibl-202 Overcomes Microenvironmental Mediated Resistance in Multiple Myeloma and Prevents PIM1 Induced CXCR4 Upregulation

Mairead Reidy, PhD, Marianne VanDijk, PhD, Michael O'Neill, PhD, Michael O'Dwyer, MD FRCPI, FRCPath
Journal: Blood
Blood (2015) 126 (23): 5350.
https://doi.org/10.1182/blood.V126.23.5350.5350
Published: 2015
Journal Articles

Concurrent Inhibition of Pim and Akt Pathways with Pim447 and Afuresertib Activates FOXO3a and Depletes c-Myc to Induce Synergistic Cell Death in Multiple Myeloma

Niamh Keane, MB BCh MRCPI, Mairead Reidy, PhD, Alessandro Natoni, PhD, Michael O'Dwyer, MD FRCPI, FRCPath
Journal: Blood
Blood (2015) 126 (23): 3007.
https://doi.org/10.1182/blood.V126.23.3007.3007
Published: 2015
Journal Articles

Initial Evaluation of Novel Dual PIM/PI3K and Triple PIM/PI3K/mTOR Inhibitors in Multiple Myeloma

Mairead Reidy, PhD, Marianne vanDijk, PhD, Niamh Keane, MB BCh BAO, Michael O'Neill, PhD, Michael E O'Dwyer, MD FRCPI, FRCPath
Journal: Blood
Blood (2014) 124 (21): 5713.
https://doi.org/10.1182/blood.V124.21.5713.5713
Published: 2014