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Journal Articles

Evaluation of Urine cfDNA for Non-Invasive Genomic Characterization in Multiple Myeloma: A Comparative Study with Serum and Bone Marrow Samples

Carl Jannes Neuse, Christoph Schliemann, Cyrus Khandanpour, Georg Lenz, Irene Ghobrial, Mark Bustoros
Journal: Blood
Blood (2024) 144 (Supplement 1): 7493.
https://doi.org/10.1182/blood-2024-210454
Published: 2024
Journal Articles

Disease Course and Risk Model Validation of Asymptomatic Waldenström Macroglobulinemia Patients - a Single Center Experience

Theresia Akhlaghi, Jose Fernandez-Rengifo, Mateo Mejia Saldarriaga, Sarah C. Rutherford, Cara Rosenbaum, Jorge Monge, Peter Martin, John N. Allan, Richard R. Furman, Ruben Niesvizky, Mark Bustoros
Journal: Blood
Blood (2024) 144 (Supplement 1): 6350.
https://doi.org/10.1182/blood-2024-210059
Published: 2024
Journal Articles

Absolute Lymphocyte Count after CAR-T Therapy Has Different Kinetics and Predicts Better Outcomes in B-Cell Malignancies

Juan Esteban Velez-Hernandez, Mateo Mejia Saldarriaga, Caitlin Unkenholz, Christian A Gordillo, Divaya Bhutani, Roger Pearse, Rajshekhar Chakraborty, Suzanne Lentzsch, Markus Y Mapara, Ruben Niesvizky, Ran Reshef, Samuel Yamshon, Mark Bustoros
Journal: Blood
Blood (2024) 144 (Supplement 1): 7160.
https://doi.org/10.1182/blood-2024-209960
Published: 2024
Journal Articles

Abnormal Serum Fixation Patterns Are a Common Event Following BCMA CAR-T Therapy in Relapsed Refractory Multiple Myeloma and Are Often Preceded By Immunological Events

Caitlin Unkenholz, Mateo Mejia Saldarriaga, Esther Ortega, Jorge Monge, Christian A Gordillo, Juan Esteban Velez-Hernandez, Divaya Bhutani, Roger Pearse, Rajshekhar Chakraborty, Suzanne Lentzsch, Ran Reshef, Ruben Niesvizky, Mark Bustoros
Journal: Blood
Blood (2024) 144 (Supplement 1): 1936.
https://doi.org/10.1182/blood-2024-210365
Published: 2024
Journal Articles

Tumor-Intrinsic and Immune Predictors of Response to Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Michelle P. Aranha, Omar Nadeem, Robert A. Redd, Michael Timonian, Sophie Magidson, Elizabeth D. Lightbody, Jean-Baptiste Alberge, Ting Wu, Junko Tsuji, Luca Bertamini, Ankit K. Dutta, Habib El-Khoury, Mark Bustoros, Jacob Laubach, Giada Bianchi, Elizabeth K. O'Donnell, Kenneth C. Anderson, Gad Getz, Lorenzo Trippa, Paul G. Richardson, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1928.
https://doi.org/10.1182/blood-2024-203684
Published: 2024
Journal Articles

Post CAR-T Peripheral Lymphocytosis and Its Kinetics Are a Potential Biomarker for Response and Immune Mediated Toxicities

Mateo Mejia Saldarriaga, Caitlin Unkenholz, Joshua A Fein, Jorge Monge, Cara Rosenbaum, Roger Pearse, Markus Mapara, Giorgio Inghirami, Suzanne Lentzsch, Ran Reshef, Ruben Niesvizky, Mark Bustoros
Journal: Blood
Blood (2023) 142 (Supplement 1): 3341.
https://doi.org/10.1182/blood-2023-187832
Published: 2023
Journal Articles

Clinical and Genomics Characteristics of Multiple Myeloma with Extramedullary Disease in the Mmrf Registry

Mateo Mejia Saldarriaga, David S Jayabalan, Aubrie Sowa, Jorge Monge, Cara A. Rosenbaum, Roger Pearse, Ruben Niesvizky, Sanjay Patel, Mark Bustoros
Journal: Blood
Blood (2022) 140 (Supplement 1): 4238–4239.
https://doi.org/10.1182/blood-2022-157191
Published: 2022
Journal Articles

Young Adults with Multiple Myeloma Have Distinct Clinical and Molecular Characteristics Compared to Older Patients

Mateo Mejia Saldarriaga, Aubrie Sowa, David S Jayabalan, Cara A. Rosenbaum, Roger Pearse, Jorge Monge, Ruben Niesvizky, Mark Bustoros
Journal: Blood
Blood (2022) 140 (Supplement 1): 9951–9952.
https://doi.org/10.1182/blood-2022-170413
Published: 2022
Journal Articles

Genomic Profiling of Smoldering Multiple Myeloma Classifies Molecular Groups with Distinct Pathogenic Phenotypes and Clinical Outcomes

Shankara Anand, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Eileen M Boyle, Yu-Tzu Tai, Carl J Neuse, Selina J Chavda, Cody J. Boehner, Mahshid Rahmat, Benny Zhitomirsky, Andrew Dunford, Ankit K. Dutta, Chip Stewart, Lorenzo Trippa, Tineke Casneuf, Efstathios Kastritis, Brian A Walker, Faith E Davies, Meletios A. Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 723.
https://doi.org/10.1182/blood-2021-150767
Published: 2021
Journal Articles

High Prevalence of Monoclonal Gammopathy in a Population at Risk: The First Results of the Promise Study

Habib El-Khoury, Jean-Baptiste Alberge, Hadley Barr, Ciara Murphy, D.J. Sakrikar, Tara Krause, David Barnidge, Mark Bustoros, Houry Leblebjian, Annie Cowan, Maya Davis, Julia Amstutz, Jacqueline Perry, Cody J. Boehner, Elizabeth D. Lightbody, Tarek H Mouhieddine, Romanos Sklavenitis-Pistofidis, Mark C Perkins, Stephen Harding, Prashant Kapoor, Clifton C. Mo, David L. Murray, Ivan M. Borrello, Gad Getz, Timothy R Rebbeck, Catherine R. Marinac, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 152.
https://doi.org/10.1182/blood-2021-149868
Published: 2021
Journal Articles

Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Response to Immunotherapy in Patients with High-Risk Smoldering Myeloma

Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Sylvia Ujwary, Robert A. Redd, Alexandra Savell, Léa Fléchon, François Aguet, Nicholas Haradhvala, Oksana Zavidij, Mark Bustoros, Sabrin Tahri, Tarek H Mouhieddine, Nang K. Su, Lily Ardente, Shankara Anand, Jacalyn Rosenblatt, Jeffrey A. Zonder, James J. Vredenburgh, Adam Boruchov, Manisha Bhutani, Saad Z. Usmani, Jeffrey V. Matous, Andrew J. Yee, Andrzej Jakubowiak, Claudia E. Paba-Prada, Julia Prescott, Jacob P. Laubach, Salomon Manier, Omar Nadeem, Paul G. Richardson, Ashraf Z. Badros, Lorenzo Trippa, Maria-Victoria Mateos, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 330.
https://doi.org/10.1182/blood-2021-147623
Published: 2021
Journal Articles

A Next Generation Liquid Biopsy Approach for Multiple Myeloma

Daniel Auclair, Mark Bustoros, MD, Carrie Cibulskis, BSc, Teni Dowdell, BSc, Svetlana Gavrilov, MD PhD, Cody J Boehner, BS, Jennifer Yesil, MSc, Steven E. Labkoff, MD, Shaadi Mehr, PhD, Romanos Sklavenitis-Pistofidis, MD, Salomon Manier, MD PhD, Elizabeth D. Lightbody, PhD, Annette S. Kim, MDPhD, Justin Rhoades, Keith L Ligon, MD PhD, Niall Lennon, PhD, Viktor Adalsteinsson, PhD, Jane Wilkinson, PhD, Hearn Jay Cho, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-136865
Published: 2020
Journal Articles

Phase II Trial of the Combination of Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Mark Bustoros, MD, Omar Nadeem, MD, Adam S Sperling, MD PhD, Giada Bianchi, MD, Lily Ardente, BS, Robert A. Redd, MS, Julia Prescott, NP, Erin Frey, RN, Kathleen Guimond, RN, Rachel Styles, BS, Kalvis Hornburg, BA, Alexandra Savell, BS, Nang Kham Su, BA, Govind Bindra, BA, Cody J Boehner, BS, Kaitlen Reyes, DNP, Houry Leblebjian, PharmD, Diane Warren, Nikhil C. Munshi, MD, Jacob P. Laubach, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 580.
https://doi.org/10.1182/blood-2019-128519
Published: 2019
Journal Articles

A Phase II Study of Daratumumab in Patients with High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma: First Report of Efficacy and Safety

Omar Nadeem, MD, Robert Redd, Laura V. Stampleman, Jeffrey V. Matous, MD, Andrew J. Yee, MD, Jeffrey A. Zonder, Andrew Kin, MD, Jacalyn Rosenblatt, MD, Mark Bustoros, MD, Julia Prescott, MSN,NP, Alexandra Savell, BS, Kathleen Guimond, RN, Erin Frey, RN, Rachel Styles, BS, Adrienne Bielawski, Cody J Boehner, BS, Nang Kham Su, BA, Multiple Myeloma Research Foundation Multiple Myeloma Research Foundation, The Leukemia & Lymphoma Society The Leukemia & Lymphoma Society, BCRP Blood Cancer Research Partnership, Adam S Sperling, MD PhD, Giada Bianchi, MD, Jacob P. Laubach, MD, Jorge J. Castillo, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Lorenzo Trippa, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1898.
https://doi.org/10.1182/blood-2019-129103
Published: 2019
Journal Articles

Pregnancy Outcomes, Risk Factors, and Gestational Cell Count Trends in Pregnant Women with Essential Thrombocythemia and Polycythemia Vera

Chi-Joan How, MD, Orly Leiva, BS, Thomas Bogue, BS, Geoffrey Fell, MS, Mark Bustoros, MD, Nathan T. Connell, MD MPH, Jean M. Connors, MD, Irene M. Ghobrial, MD, Nancy Higgins, Nicholas A Jessop, David J. Kuter, Jennifer Lombardi Story, Ann Mullally, MD, Valentina Nardi, MD, Donna S Neuberg, ScD, Rachel Styles, BS, Jeffrey I. Zwicker, MD, Gabriela S. Hobbs, MD, Annemarie E Fogerty, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4172.
https://doi.org/10.1182/blood-2019-127058
Published: 2019
Journal Articles

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients

Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Chia-Jen Liu, Mairead Reidy, Oksana Zavidij, Daisy Huynh, Patrick Henrick, Alexandra Savell, Kaitlen Reyes, Bradley Rivotto, Mark Bustoros, Adriana Perilla-Glen, Lorenzo Trippa, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial
Journal: Blood
Blood (2018) 132 (24): 2608–2612.
https://doi.org/10.1182/blood-2018-07-863241
Published: 2018
Journal Articles

Dissecting the Epigenetic Landscape of Smoldering, Newly Diagnosed and Relapsed Multiple Myeloma Revealed IRAK3 As a Marker of Disease Progression

Mahshid Rahmat, PhD, Nicholas Haradhvala, BA, Romanos Sklavenitis-Pistofidis, MD, Jihye Park, PhD, Daisy Huynh, MS, Mark Bustoros, MD, Brianna Berrios, BS, Mairead Reidy, PhD, Adriana Perilla-Glen, Bradley Rivotto, BS, Kalvis Hornburg, BA, David M. Dorfman, MD, PhD, Jonathan D. Licht, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3896.
https://doi.org/10.1182/blood-2018-99-115046
Published: 2018
Journal Articles

Single-Cell RNA Sequencing Reveals Compromised Immune Microenvironment in Precursor Stages of Multiple Myeloma

Oksana Zavidij, PhD, Nicholas Haradhvala, BA, Tarek H Mouhieddine, MD, Jihye Park, PhD, Romanos Pistofidis, MD, Mairead Reidy, PhD, Daisy Huynh, MS, Marzia Capelletti, PhD, Brianna Berrios, BS, Mahshid Rahmat, PhD, Mark Bustoros, MD, Chia-Jen Liu, MD, Meng Xiao He, AB, Yosef Maruvka, PhD, Bradley Rivotto, BS, Kalvis Hornburg, BA, Melissa Goldman, PhD, Eliezer Van Allen, MD, Steven A McCarroll, PhD, Jamil Azzi, MD, Gad Getz, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2603.
https://doi.org/10.1182/blood-2018-99-114145
Published: 2018
Journal Articles

The Role of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Multiple Myeloma: Immunomodulator Maintenance Post Autologous Stem Cell Transplant (ASCT) Predicts Better Outcome

Tarek H Mouhieddine, MD, Jihye Park, PhD, Robert A. Redd, MS, Christopher J. Gibson, MD, Salomon Manier, MD PhD, Amin H Nassar, MD, Marzia Capelletti, PhD, Daisy Huynh, MS, Mark Bustoros, MD, Romanos Sklavenitis-Pistofidis, MD, Kalvis Hornburg, BA, Henry Dumke, BS, Muhieddine M Itani, MD, Cody J Boehner, Chia-Jen Liu, MD PhD, Saud H AlDubayan, MD, Brendan Reardon, Eliezer Van Allen, MD, Daniel Auclair, PhD, Robert L. Schlossman, MD, Nikhil Munshi, MD, Kenneth Anderson, MD, David P. Steensma, MD, Jacob Laubach, MD, Paul Richardson, Jerome Ritz, MD PhD, Benjamin L. Ebert, MDPhD, Robert J. Soiffer, MD, Donna S Neuberg, ScD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 749.
https://doi.org/10.1182/blood-2018-99-113059
Published: 2018
Journal Articles

Phase II Trial of the Combination of Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Mark Bustoros, MD, Chia-jen Liu, MD, Kaitlen Reyes, NP, Kalvis Hornburg, BA, Kathleen Guimond, RN, Rachel Styles, Alexandra Savell, BS, Brianna Berrios, BS, Diane Warren, Henry Dumke, BS, Bradley Rivotto, BS, Patrick Henrick, BS, Emily Scranton, NP, Houry Leblebjian, PharmD, Kirsten Meid, MPH, Robert L. Schlossman, MD, Nikhil Munshi, MD, Jacob Laubach, MD, Kenneth C. Anderson, MD, Paul Richardson, Irene M. Ghobrial, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 804.
https://doi.org/10.1182/blood-2018-99-117871
Published: 2018