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Eileen M Boyle
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Journal Articles

A Novel Segmentation-Based Purity-Informed Approach Accurately Detects Total Copy Number and Its Subclonal Fraction in Myeloma Targeted Panel Sequencing Data

Naser Ansari-Pour, Mohammad Kazeroun, Seyed Alireza Hasheminasab, Emma J Lyon, Bethan Hudson-Lund, Evie Fitzsimons, Gaurav Agarwal, Kara-Louise Royle, Matthew W. Jenner, Martin F Kaiser, Karthik Ramasamy, Kwee Yong, Eileen M Boyle, Sarah Gooding, Angela Hamblin, Anjan Thakurta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1909.
https://doi.org/10.1182/blood-2024-207973
Published: 2024
Journal Articles

Evaluating Barriers to Enrolment into Multiple Myeloma (MM) Clinical Trials: Results from Health Care Professionals and Patient Survey from the UK Myeloma Research Alliance Equity, Diversity and Inclusivity (EDI) Working Group

Selina J Chavda, Marquita Camilleri, Andrew Hall, Laura Clayton, Fatjon Dekaj, Dunsi Bolarinwa, Chantelle Hughes, Doina Levinte, Eileen M Boyle, Martin F Kaiser, Rachel O'Malley, Emma Williams, Andie Guy, Pinkie Chambers, Sandra CM Quinn, Rakesh Popat
Journal: Blood
Blood (2024) 144 (Supplement 1): 3792.2.
https://doi.org/10.1182/blood-2024-205315
Published: 2024
Journal Articles

Risk Assignment Using the Myeloma Genome Project Panel: A Comparison to Standard of Care Genetic Testing within the UK-MRA RADAR Trial

Sarah Gooding, Kara-Louise Royle, Mohammad Kazeroun, Robert Cicero, Laura Chiecchio, Dipal Mehta, Emma J Lyon, Bethan Hudson-Lund, Jasmin Rahman, Khrystal McBean, Martin F Kaiser, Catherine Olivier, Doina Levinte, Charlotte Kennaway, Dean Smith, Jonathan Sive, Ceri Bygrave, Guy Pratt, Michael A. Chapman, Graham Jackson, Rakesh Popat, Christopher Parrish, Gordon Cook, Angela Hamblin, Naser Ansari-Pour, David A. Cairns, Anjan Thakurta, Karthik Ramasamy, Eileen M Boyle, Kwee Yong, Matthew W. Jenner
Journal: Blood
Blood (2024) 144 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2024-209772
Published: 2024
Journal Articles

Tumour-Intrinsic Features Shape T-Cell Differentiation through Myeloma Disease Evolution

Kane A Foster, Elise Rees, Louise Ainley, Eileen M Boyle, Lydia Sarah Hui Lee, Gwennan Ward, Daria Galas-Filipowicz, Anna Mikolajczak, Emma J Lyon, Dylan Jankovic, Jasmine Rahman, Mahima Turakhia, Imran Uddin, Gordon Beattie, Yvette Hoade, Catherine Zhu, James L Reading, Ieuan Walker, Michael A. Chapman, Karthik Ramasamy, Javier Herrero, Benny Chain, Sergio A Quezada, Kwee Yong
Journal: Blood
Blood (2024) 144 (Supplement 1): 669.
https://doi.org/10.1182/blood-2024-203306
Published: 2024
Journal Articles

Tracking the Earliest Genomic Events in Multiple Myeloma Life-History

Anthony Cirrincione, Bachisio Ziccheddu, Kylee H Maclachlan, Alexandra M. Poos, Monika Chojnacka, Benjamin Diamond, Eileen M Boyle, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Faith E. Davies, Neha Korde, Marc S Raab, Niels Weinhold, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 1553–1555.
https://doi.org/10.1182/blood-2022-164742
Published: 2022
Journal Articles

The Mutagenic Impact of Radiotherapy in Multiple Myeloma

Benjamin Diamond, Alexandra M Poos, Bachisio Ziccheddu, Kylee H Maclachlan, Yanming Zhang, Saad Usmani, Eileen M Boyle, Faith E Davies, Gareth J. Morgan, Ola Landgren, Marc S Raab, Francesco Maura, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 7125–7126.
https://doi.org/10.1182/blood-2022-166531
Published: 2022
Journal Articles

Structural Heterogeneity of Chromosome 1q Drives Outcome in Newly Diagnoses Myeloma

Eileen M Boyle, Patrick Blaney, James Stoeckle, Yubao Wang, Hussein Ghamlouch, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, David Kaminetzsky, Marc Braunstein, Lydia Montes, Jill Corre, Even H Rustad, Ola Landgren, Francesco Maura, Benedetto Bruno, Aristotelis Tsirigos, Brian A. Walker, Faith E Davies, Dylan Gagler, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 4253–4254.
https://doi.org/10.1182/blood-2022-165467
Published: 2022
Journal Articles

Variability in Pattern of Mutational Signatures in Multiple Myeloma As a Function of Racial Origin

Patrick Blaney, Eileen M Boyle, Kylee H Maclachlan, Louis S. Williams, Dylan Gagler, Parvathi Sudha, Alexandra M Poos, Yubao Wang, Hussein Ghamlouch, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, David Kaminetzsky, Marc Braunstein, David Coffey, Benjamin Diamond, Bachisio Ziccheddu, Dickran Kazandjian, Urvi A Shah, Elizabeth E. Brown, Elisabet E. Manasanch, Alexander M Lesokhin, Niels Weinhold, Brian A. Walker, Saad Usmani, Ola Landgren, Faith E Davies, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 430–432.
https://doi.org/10.1182/blood-2022-167390
Published: 2022
Journal Articles

Fc-Mediated Antibody Effector Function, Inflammation Resolution and Oligoclonality on TCR Rearrangements Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Treated with Immunotherapy Regimens

Eileen M Boyle, Francesco Maura, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Bachisio Ziccheddu, Yubao Wang, Emily Guzman, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, James E Hoffman, Dickran Kazandjian, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E Davies, Saad Usmani, Neha Korde, Ola Landgren, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 249–251.
https://doi.org/10.1182/blood-2022-165500
Published: 2022
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

Genomic Profiling of Smoldering Multiple Myeloma Classifies Molecular Groups with Distinct Pathogenic Phenotypes and Clinical Outcomes

Shankara Anand, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Eileen M Boyle, Yu-Tzu Tai, Carl J Neuse, Selina J Chavda, Cody J. Boehner, Mahshid Rahmat, Benny Zhitomirsky, Andrew Dunford, Ankit K. Dutta, Chip Stewart, Lorenzo Trippa, Tineke Casneuf, Efstathios Kastritis, Brian A Walker, Faith E Davies, Meletios A. Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 723.
https://doi.org/10.1182/blood-2021-150767
Published: 2021
Journal Articles

Multiomic Mapping of Copy Number and Structural Variation on Chromosome 1 (Chr1) Highlights Multiple Recurrent Disease Drivers

Patrick Blaney, Eileen M Boyle, Yubao Wang, Hussein Ghamlouch, Jinyoung Choi, Louis Williams, Stoeckle James, Ariel Siegel, Beatrice Razzo, Marc Braunstein, David Kaminetzky, Arnaldo A Arbini, Benedetto Bruno, Jill Corre, Lydia Montes, Daniel Auclair, Faith E. Davies, Aristotelis Tsirigos, Even H Rustad, Francesco Maura, Ola Landgren, Michael A Bauer, Brian Walker, Gareth Morgan
Journal: Blood
Blood (2021) 138 (Supplement 1): 721.
https://doi.org/10.1182/blood-2021-148439
Published: 2021
Journal Articles

Hispanic or Latin American Ancestry Is Associated with a Similar Genomic Profile and a Trend Toward Inferior Outcomes in Newly Diagnosed Multiple Myeloma As Compared to Non-Hispanic White Patients in the Multiple Myeloma Research Foundation (MMRF) CoMMpassstudy

Louis Williams, Patrick Blaney, Eileen M Boyle, Hussein Ghamlouch, Yubao Wang, Jinyoung Choi, Michael A Bauer, Ariel Siegel, James Stoeckle, Beatrice Razzo, Daniel Auclair, David Kaminetzky, Marc Braunstein, Benedetto Bruno, Arnaldo A. Arbini, Brian A Walker, Faith E. Davies, Gareth J Morgan
Journal: Blood
Blood (2021) 138 (Supplement 1): 4117.
https://doi.org/10.1182/blood-2021-148854
Published: 2021
Journal Articles

Unifying the Definition of High-Risk in Multiple Myeloma

Ariel Siegel, Eileen M Boyle, Patrick Blaney, Yubao Wang, Hussein Ghamlouch, Jinyoung Choi, Jessica Caro, Louis Williams, Beatrice Razzo, Arnaldo A. Arbini, Marc Braunstein, David Kaminetzky, Daniel Auclair, Charlotte Pawlyn, David Cairns, Graham Jackson, Brian Walker, Benedetto Bruno, Gareth J. Morgan, Faith E. Davies
Journal: Blood
Blood (2021) 138 (Supplement 1): 2714.
https://doi.org/10.1182/blood-2021-148502
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Genomic and Immune Signatures Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone (D-KRd)

Francesco Maura, Eileen M Boyle, Benjamin Diamond, Patrick Blaney, Hussein Ghamlouch, Bachisio Ziccheddu, Yubao Wang, Kylee H Maclachlan, James E. Hoffman, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Dickran Kazandjian, Gunjan L Shah, Heather J Landau, David J. Chung, Sergio Giralt, Benedetto Bruno, Yanming Zhang, Arnaldo A Arbini, Ahmet Dogan, Alexander Lesokhin, Faith E Davies, Neha Korde, Gareth J Morgan, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 325.
https://doi.org/10.1182/blood-2021-149112
Published: 2021
Journal Articles

Treatment with Temozolomide and Ibrutinib in Recurrent/Refractory Primary (PCNSL) and Secondary CNS Lymphoma (SCNSL)

Loïc Renaud, MD MSc, Jean-Baptiste Bossard, MD MSc, Louis Terriou, Nathalie Cambier, MD, Guillaume Chanteau, Benjamin Carpentier, MD, Sarah Barbieux, MD, Mathieu Wemeau, MD, Julia Hieulle, Eileen M Boyle, MDMSc, Franck Morschhauser, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-138764
Published: 2020
Journal Articles

Influence of Aging Processes on the Biology and Outcome of Multiple Myeloma

Eileen M Boyle, MDMSc, Louis Williams, MD MBA, Patrick Blaney, Cody Ashby, PhD, Michael A Bauer, PhD, Brian A Walker, PhD, Jinyoung Choi, PhD, Jessica Caro, MD, Beatrice Razzo, MD, Arnaldo A. Arbini, MD, David Kaminetzky, MD, Marc Braunstein, MDPhD, Francesco Maura, MD, Yubao Wang, PhD, Ola Landgren, MD PhD, James Stoeckle, MD, Kylee H Maclachlan, MBChB, PhD, Rachel Litke, Faith E. Davies, Gareth Morgan, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-138787
Published: 2020
Journal Articles

Impact of Etiological Cytogenetic Abnormalities on Immunoparesis and Progression-Free and Overall Survival in Newly Diagnosed Multiple Myeloma

Jessica Caro, MD, David Cairns, MSc, PhD, Tom Menzies, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Eileen M Boyle, MD MSc, Gareth Morgan, MD PhD, Gordon Cook, MB ChB, PhD, Martin F. Kaiser, MD FRCP, FRCPath, Roger G Owen, MD, Walter M Gregory, PhD, Graham H Jackson, MD MA, MB BS, FRCP, FRCPath, Brian Walker, PhD, Jennifer LJ Heaney, PhD, Mark T Drayson, MB ChB, PhD FRCPath, Faith E. Davies
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-133516
Published: 2020
Journal Articles

The Role of PHF19 As a Promoter of Tumorigenicity and Therapeutic Target in Multiple Myeloma

Carolina D. Schinke, MD, Pingping Qu, Shmuel Yaccoby, PhD, Valeriy V Lyzogubov, MD PhD, Veronica MacLeod, Eileen M Boyle, Randal Shelton, Wen Ling, PhD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Bart Barlogie, MD PhD, Frits van Rhee, MD PhD, Brian A Walker, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 508.
https://doi.org/10.1182/blood-2019-130595
Published: 2019