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Journal Articles

Tumour-Intrinsic Features Shape T-Cell Differentiation through Myeloma Disease Evolution

Kane A Foster, Elise Rees, Louise Ainley, Eileen M Boyle, Lydia Sarah Hui Lee, Gwennan Ward, Daria Galas-Filipowicz, Anna Mikolajczak, Emma J Lyon, Dylan Jankovic, Jasmine Rahman, Mahima Turakhia, Imran Uddin, Gordon Beattie, Yvette Hoade, Catherine Zhu, James L Reading, Ieuan Walker, Michael A. Chapman, Karthik Ramasamy, Javier Herrero, Benny Chain, Sergio A Quezada, Kwee Yong
Journal: Blood
Blood (2024) 144 (Supplement 1): 669.
https://doi.org/10.1182/blood-2024-203306
Published: 2024
Journal Articles

And-Gate CAR T-Cells to Improve Tumour Specificity and Targeting of Low-Expression Antigens in Multiple Myeloma

Georgina S.F. Anderson, Ieuan Walker, James P Roy, Michael A. Chapman
Journal: Blood
Blood (2023) 142 (Supplement 1): 751.
https://doi.org/10.1182/blood-2023-187418
Published: 2023
Journal Articles

High Neoantigen Load Confers a Major Benefit from Autologous Stem Cell Transplantation Compared to Consolidation in Newly Diagnosed Multiple Myeloma

Ieuan Walker, Venetia D'Arcy, Kane Foster, Garima Khandelwal, Georgina S.F. Anderson, William Wilson, Evie Fitzsimons, Daria Galas-Filipowicz, Rakesh Popat, Karthik Ramasamy, Matthew Streetly, Ceri Bygrave, Reuben Benjamin, Ruth M de Tute, Marquita Camilleri, Selina J Chavda, Gavin Pang, Sumaiya Kamora, James D. Cavenagh, Elizabeth Phillips, Laura Clifton-Hadley, Charlotte Tyson, Fuad Fananapazir, Krupali Parikh, Roger Owen, Javier Herrero, Kwee Yong, Michael A. Chapman
Journal: Blood
Blood (2023) 142 (Supplement 1): 3306.
https://doi.org/10.1182/blood-2023-186318
Published: 2023
Journal Articles

Development of the First SEMA4A CAR-T Cell Targeting Multiple Myeloma

James P Roy, Georgina S.F. Anderson, Ieuan Walker, Michael A Chapman
Journal: Blood
Blood (2022) 140 (Supplement 1): 9961–9962.
https://doi.org/10.1182/blood-2022-168968
Published: 2022
Journal Articles

Developing a Flow Cytometric Signature of Carfilzomib Responsiveness in Myeloma

Ieuan Walker, Venetia D'arcy, Antonio Rodriguez Romera, Georgina Anderson, Anna Aubareda, James Roy, Garima Khandelwal, William Wilson, Evelyn Fitzsimons, Daria Galas-Filipowicz, Kane Foster, Rakesh Popat, Karthik Ramasamy, Matthew Streetly, Ceri Bygrave, Reuben Benjamin, Ruth M. de Tute, Marquita Camilleri, Selina J Chavda, Gavin Pang, Tushhar Dadaga, Sumaiya Kamora, James Cavenagh, Elizabeth H. Phillips, Laura Clifton-Hadley, Roger G Owen, Javier Herrero, Kwee Yong, Michael A Chapman
Journal: Blood
Blood (2022) 140 (Supplement 1): 10106–10107.
https://doi.org/10.1182/blood-2022-169882
Published: 2022
Journal Articles

Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma

Georgina S.F. Anderson, Jose Ballester-Beltran, George Giotopoulos, Jose A. Guerrero, Sylvanie Surget, James C. Williamson, Tsz So, David Bloxham, Anna Aubareda, Ryan Asby, Ieuan Walker, Lesley Jenkinson, Elizabeth J. Soilleux, James P. Roy, Ana Teodósio, Catherine Ficken, Leah Officer-Jones, Sara Nasser, Sheri Skerget, Jonathan J. Keats, Peter Greaves, Yu-Tzu Tai, Kenneth C. Anderson, Marion MacFarlane, James E. Thaventhiran, Brian J.P. Huntly, Paul J. Lehner, Michael A. Chapman
Journal: Blood
Blood (2022) 139 (16): 2471–2482.
https://doi.org/10.1182/blood.2021015161
Published: 2022
Includes: Supplemental data
Journal Articles

SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence

Brief Report
Jie Gao, Eirini Sidiropoulou, Ieuan Walker, Joanna A. Krupka, Karol Mizielinski, Zelvera Usheva, Shamith A. Samarajiwa, Daniel J. Hodson
Journal: Blood
Blood (2021) 138 (11): 959–964.
https://doi.org/10.1182/blood.2020010432
Published: 2021
Includes: Supplemental data
Journal Articles

Allogeneic Anti-Bcma CAR-T Cells Show Tumour Specific Killing Against Primary Multiple Myeloma Cells from Different Genomic Sub-Groups

Ana M Metelo, PhD, Ieuan Walker, BSc, MSc, MBBS, Agnieszka Jozwik, PhD, Charlotte Graham, MRCP, BSc, MBBS, Charlotte Attwood, BMedSci, MBBS, MRCP, FRCPath, Katy Sanchez, BSc, MSc, Alan Dunlop, BSc, MSc, Kirsty Cuthill, FRCPath,MBBS,MRCP,PhD, Carmel Rice, FRACP, FRCPA, MBBS, Matthew Streetly, MD, Trevor Bentley, BSc, Bijan Boldajipour, PhD, Cesar Sommer, PhD, Barbra Sasu, PhD, Reuben Benjamin, FRCPath, MRCP, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1834.
https://doi.org/10.1182/blood-2019-124312
Published: 2019
Journal Articles

Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease

Clinical Trials & Observations
Susan Branford, Paul Wang, David T. Yeung, Daniel Thomson, Adrian Purins, Carol Wadham, Nur Hezrin Shahrin, Justine E. Marum, Nathalie Nataren, Wendy T. Parker, Joel Geoghegan, Jinghua Feng, Naranie Shanmuganathan, Martin C. Mueller, Christian Dietz, Doris Stangl, Zoe Donaldson, Haley Altamura, Jasmina Georgievski, Jodi Braley, Anna Brown, Christopher Hahn, Ieuan Walker, Soo-Hyun Kim, Soo-Young Choi, Sa-Hee Park, Dong-Wook Kim, Deborah L. White, Agnes S. M. Yong, David M. Ross, Hamish S. Scott, Andreas W. Schreiber, Timothy P. Hughes
Journal: Blood
Blood (2018) 132 (9): 948–961.
https://doi.org/10.1182/blood-2018-02-832253
Published: 2018
Includes: Supplemental data
Journal Articles

Novel Fusion Genes at CML Diagnosis Reveal a Complex Pattern of Genomic Rearrangements and Sequence Inversions Associated with the Philadelphia Chromosome in Patients with Early Blast Crisis

Justine E Marum, PhD, Paul PS Wang, PhD, Doris Stangl, PhD, David T. Yeung, BSc, MBBS, FRACP, FRCPA, Martin C. Mueller, Christian T. Dietz, PhD, Ieuan Walker, MSc, BSc, MBBS, Nathalie Nataren, BSc, Zoe Donaldson, BSc, Wendy T Parker, PhD, David M. Ross, MBBS, PhD FRACP, FRCPA, Hamish S Scott, BSc, PhD FFSc (RCPA), FAHMS, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, FAAHMS, Andreas W Schreiber, PhD, Susan Branford, PhD FFSc (RCPA)
Journal: Blood
Blood (2016) 128 (22): 1219.
https://doi.org/10.1182/blood.V128.22.1219.1219
Published: 2016
Journal Articles

High Incidence of Mutated Cancer-Associated Genes at Diagnosis in CML Patients with Early Transformation to Blast Crisis

Susan Branford, PhDFFSc (RCPA), Paul PS Wang, PhD, Wendy Tara Parker, PhD, David Yeung, Justine E Marum, PhD, Doris Stangl, PhD, Zoe Donaldson, Alexandra Yeoman, Nathalie Nataren, Ieuan Walker, Leanne Purins, Bradley Chereda, PhD, Christopher N Hahn, PhD, Hamish S Scott, BSc, PhD FFSc (RCPA), Andreas Schreiber, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2015) 126 (23): 600.
https://doi.org/10.1182/blood.V126.23.600.600
Published: 2015