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Journal Articles

Selinexor, Venetoclax, and Dexamethasone in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma (SELVEDge Study)

Dickran Kazandjian, Kellye Koubek, Andrew Kowalski, Stephanie Mompoint, Rabia Bukhari, Maila Wilson, Jeremy Deni, Sydney Jackson, Yahirini Rodriguez-Martinez, Justin Llano, Michelle Armogan, Stephanie Fernandes, Maurizio Affer, Sana Chaudhry, Tulasigeri M Totiger, Catalina Amador, Melinda Boone, Jennifer Rose Chapman-Fredricks, Mike Georgiou, Russ Kuker, Katie Thoren, Yi Zhou, David G. Coffey, Marcella Kaddoura, Francesco Maura, Benjamin Diamond, James Edward Hoffman, Justin Taylor, Ola Landgren
Journal: Blood
Blood (2024) 144 (Supplement 1): 7049.
https://doi.org/10.1182/blood-2024-193966
Published: 2024
Journal Articles

The LSD1 Inhibitor Ory-1001 (ladademstat) in Combination with Menin Inhibitor SNDX-5613 (revumenib) Has Synergistic in Vitro Activity in KMT2A -Rearranged AML Models

Mina M. Tayari, Tulasigeri M Totiger, Ramin Shiekhattar, Justin Taylor, Justin M. Watts
Journal: Blood
Blood (2023) 142 (Supplement 1): 5691.
https://doi.org/10.1182/blood-2023-190309
Published: 2023
Journal Articles

Altered RNA Export in SF3B1 Mutants Increases Sensitivity to Nuclear Export Inhibition

Sana Chaudhry, Felipe Beckedorff, Tulasigeri M Totiger, Maurizio Affer, Nidhi Hariramani, Skye Montoya, Alyssa Cornista, Daniel Bilbao, Evan R. Roberts, Jumana Afaghani, Jose Antonio Rodríguez, Eric Wang, Justin Taylor
Journal: Blood
Blood (2023) 142 (Supplement 1): 44.
https://doi.org/10.1182/blood-2023-182877
Published: 2023
Journal Articles

Selinexor, Venetoclax, and Dexamethasone in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma (SELVEDge Study)

Dickran Kazandjian, Justin Taylor, Kellye Koubek, Rabia Bukhari, Maila Wilson, Isabella Schiwy, Yahirini Rodriguez-Martinez, Justin Llano, Stephanie Fernandes, Michelle Armogan, Maurizio Affer, Sana Chaudhry, Tulasigeri M Totiger, Catalina Amador, Melinda Boone, Jennifer R. Chapman-Fredricks, Mike Georgiou, Russ Kuker, Katie Thoren, Yi Zhou, Benjamin Diamond, James E. Hoffman, Ola Landgren
Journal: Blood
Blood (2023) 142 (Supplement 1): 6740.
https://doi.org/10.1182/blood-2023-180939
Published: 2023
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders

Skye Montoya, Jessie Bourcier, Meghan C. Thompson, Mark Noviski, May Tan, Eric Wang, Xiaoli Mi, Nivetha Brathaban, Carla Barrientos Risso, Daniel Tsai, Jordan Ye, Jacob Jahn, Gabriel Pardo, Lee Cabuhat, Ryan Notti, Alejandro Pardo, Maurizio Affer, Stephanie Yung, James Luliano, Janine Powers, Daniel W Robbins, Vindhya Nawaratne, Tulasigeri M Totiger, Camila Pena-Velasquez, Joanna M. Rhodes, Andrew D. Zelenetz, Lindsey E. Roeker, Hao Lu, Adam Linley, Anthony R. Mato, Omar Abdel-Wahab, Justin Taylor
Journal: Blood
Blood (2022) 140 (Supplement 1): 1811–1813.
https://doi.org/10.1182/blood-2022-163268
Published: 2022
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

A Phase II Clinical Trial of E7820 for Patients with Relapsed/Refractory Myeloid Malignancies with Mutations in Splicing Factor Genes

Jan Philipp Bewersdorf, Maximilian F. Stahl, Justin Taylor, Namrata Sonia Chandhok, Justin Watts, Andriy Derkach, Mateusz Wysocki, Victoria Kostantakis, Sydney X. Lu, Jessie Bourcier, Simon Hogg, Tulasigeri M Totiger, Omar Abdel-Wahab, Eytan Stein
Journal: Blood
Blood (2022) 140 (Supplement 1): 9065–9067.
https://doi.org/10.1182/blood-2022-156830
Published: 2022
Journal Articles

XPO1 Overexpression Is a Mechanism of Resistance to Eprenetapopt and 5-Azacitidine Therapy That Can be Therapeutically Exploited for the Treatment of TP53 Mutated Myeloid Malignancies

Traci L. Kruer, Ariel Quintana, Meghan Ferrall-Fairbanks, Ling Zhang, Hannah Newman, Amy F McLemore, Qin Yang, Nana Bencrentsil, Rami S. Komrokji, Sana Chaudhry, Tulasigeri M Totiger, Maria Ken E. Figueroa, Justin Taylor, David A. Sallman, Eric Padron
Journal: Blood
Blood (2022) 140 (Supplement 1): 99–100.
https://doi.org/10.1182/blood-2022-169765
Published: 2022
Journal Articles

Combination Venetoclax and Selinexor Effective in Relapsed/Refractory Multiple Myeloma with Translocation t(11;14)

Nina Nguyen, Sana Chaudhry, Tulasigeri M Totiger, Skye Montoya, Jumana Afaghani, Terrence Bradley, Francesco Maura, Dickran Kazandjian, Jennifer R Chapman, Ola Landgren, James E. Hoffman, Justin Taylor
Journal: Blood
Blood (2021) 138 (Supplement 1): 2270.
https://doi.org/10.1182/blood-2021-146925
Published: 2021