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Namrata Sonia Chandhok
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Journal Articles

Distinct SF3B1 Allele HEAT Repeat Location Is Associated with Co-Occurring Mutation Patterns in MDS

David Bared Dukenik, Deborah Soong, Frank Scarpa, Julia Anderson, Hua Li, Viji Udayakuma, Justin M. Watts, Yazan F. Madanat, Mikkael A. Sekeres, Namrata Sonia Chandhok, Justin Taylor
Journal: Blood
Blood (2023) 142 (Supplement 1): 3242.
https://doi.org/10.1182/blood-2023-181191
Published: 2023
Journal Articles

Clinical Implications of TP53 Mutations/Allelic State in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Treated with Hypomethylating Agents (HMA)- a Multicenter, Retrospective Analysis from the Validate Database

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Hunter Cochran, Rahul Ramaswamy, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, David A Sallman, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1002.
https://doi.org/10.1182/blood-2023-186875
Published: 2023
Journal Articles

Impact of Type of Hypomethylating Agent (HMA) Used on Outcomes of Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) - a Large, Multicenter, Retrospective Analysis

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Rahul Ramaswamy, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Carmelo Gurnari, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4613.
https://doi.org/10.1182/blood-2023-178728
Published: 2023
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Were Treated with Hypomethylating Agents (HMA)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Rahul Ramaswamy, Ameera Rose, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3240.
https://doi.org/10.1182/blood-2023-186340
Published: 2023
Journal Articles

E7820, an Anti-Cancer Sulfonamide, in Combination with Venetoclax in Patients with Splicing Factor Mutant Myeloid Malignancies: A Phase II Clinical Trial

Jan Philipp Bewersdorf, Namrata Sonia Chandhok, Justin M. Watts, Andriy Derkach, Omar Abdel-Wahab, Eytan M. Stein, Justin Taylor
Journal: Blood
Blood (2023) 142 (Supplement 1): 1547.
https://doi.org/10.1182/blood-2023-182369
Published: 2023
Journal Articles

A Phase 1a/b Trial of Luxeptinib (CG-806) in Patients with Relapsed/Refractory B-Cell Malignancies or Acute Myeloid Leukemia and Evaluation of New G3 Formulation

Aaron D. Goldberg, Felipe Samaniego, Maro Ohanian, Paul B. Koller, Namrata Sonia Chandhok, Ahad A. Sadiq, Daruka Mahadevan, Mohamad A. Cherry, Jessica K. Altman, John M. Burke, Michael Z. Koontz, J. C. C Villasboas, Ben K. Tomlinson, Laura E. Finn, Erin G Reid, Jason Melear, Victor Priego, Patrick Cobb, Elizabeth Heritage Cull, Paul Conkling, David Cosgrove, Lindsey E. Roeker, Eric Tam, Donna Nguyen Haney, Jia Hu, Ranjeet Sinha, Nawazish Khan, William G. Rice, Rafael Bejar
Journal: Blood
Blood (2023) 142 (Supplement 1): 5953.
https://doi.org/10.1182/blood-2023-181151
Published: 2023
Journal Articles

Validation of the Composite Complete Response (cCR) Definitions in the International Working Group (IWG) 2023 Criteria in Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Treated with Hypomethylating Agents (HMA) - a Large, Multicenter, Retrospective Analysis from the Validate Database

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 324.
https://doi.org/10.1182/blood-2023-180299
Published: 2023
Journal Articles

Evaluation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) with Missing Molecular Data

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, David A Sallman, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4607.
https://doi.org/10.1182/blood-2023-187053
Published: 2023
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Underwent Allogenic Stem Cell Transplantation (HSCT)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Ameera Rose, Gail J. Roboz, Eunice S. Wang, Benjamin Rolles, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2023-186578
Published: 2023
Journal Articles

Impaired Early Spliceosome Complex Assembly Underlies Gene Body Elongation Transcription Defect in SF3B1K700E

Prajwal Boddu, Abhishek Gupta, Rahul Roy, barbara De La Pena Avalos, Anne Olazabal Herrero, Joshua Zimmer, Matthew Simon, Namrata Sonia Chandhok, Darren King, Nils Neuenkirchen, Elois Dray, Haifan Lin, Gary Kupfer, Amit Verma, Karla Neugebauer, Manoj Pillai
Journal: Blood
Blood (2023) 142 (Supplement 1): 714.
https://doi.org/10.1182/blood-2023-187303
Published: 2023
Journal Articles

Impact of Pre-Transplant Molecular and Cytogenetic Remission on Outcomes of Allogeneic Stem Cell Transplant in Patients with Myelodysplastic Syndrome

Shivani Handa, Namrata Sonia Chandhok, Sudhamsh Reddy Desai, Asem Berkalieva, Erin Moshier, Douglas Tremblay, Lewis R. Silverman, Trent Wang, Uroosa Ibrahim, Aditi Shastri, Jonathan Feld
Journal: Blood
Blood (2023) 142 (Supplement 1): 3239.
https://doi.org/10.1182/blood-2023-190346
Published: 2023
Journal Articles

Toxicity and Outcomes in Octo- and Nonagenarians with AML Treated with Venetoclax and Hypomethylating Agent Therapy

Ellen Madarang, Jillian Lykon, Wei Zhao, Mikkael A. Sekeres, Terrence Bradley, Namrata Sonia Chandhok, Justin Taylor, Tulay Koru-Sengul, Sunil G. Iyer, Jacopo Nanni, Cristina Papayannidis, Ryan M Miller, Ashwin Kishtagari, Michael R. Savona, Jason Gilbert, Daniel A. Pollyea, David A. Sallman, Najla Al Ali, Rami S. Komrokji, Justin Watts
Journal: Blood
Blood (2022) 140 (Supplement 1): 3306–3308.
https://doi.org/10.1182/blood-2022-170771
Published: 2022
Journal Articles

A Phase II Clinical Trial of E7820 for Patients with Relapsed/Refractory Myeloid Malignancies with Mutations in Splicing Factor Genes

Jan Philipp Bewersdorf, Maximilian F. Stahl, Justin Taylor, Namrata Sonia Chandhok, Justin Watts, Andriy Derkach, Mateusz Wysocki, Victoria Kostantakis, Sydney X. Lu, Jessie Bourcier, Simon Hogg, Tulasigeri M Totiger, Omar Abdel-Wahab, Eytan Stein
Journal: Blood
Blood (2022) 140 (Supplement 1): 9065–9067.
https://doi.org/10.1182/blood-2022-156830
Published: 2022
Journal Articles

A Phase 1a/b Dose Escalation Study of the FLT3/BTK Inhibitor Luxeptinib (CG-806) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Aaron D Goldberg, Maro Ohanian, Paul B. Koller, Mohamad Cherry, Jessica K. Altman, Benjamin Tomlinson, Namrata Sonia Chandhok, Donna Nguyen Haney, Jia Hu, Ranjeet Kumar Sinha, William G Rice, Rafael Bejar
Journal: Blood
Blood (2022) 140 (Supplement 1): 6220–6221.
https://doi.org/10.1182/blood-2022-167759
Published: 2022
Journal Articles

Outcomes for Hispanic Patients with Acute Leukemia Treated at Academic Centers

Namrata Sonia Chandhok, Ameena Shrestha, Justin M Watts, Terrence Bradley, Mikkael A. Sekeres
Journal: Blood
Blood (2021) 138 (Supplement 1): 2282.
https://doi.org/10.1182/blood-2021-151250
Published: 2021
Journal Articles

Octogenarians with AML Can Have Durable Remissions with Venetoclax and Hypomethylating Agent Therapy Despite Significant Dose Reductions

Ellen Madarang, Jillian Lykon, Wenhui Li, Sunil Iyer, Michele Stanchina, Nina Nguyen, Terrence Bradley, Mikkael A. Sekeres, Justin Taylor, Namrata Sonia Chandhok, Justin Watts
Journal: Blood
Blood (2021) 138 (Supplement 1): 1259.
https://doi.org/10.1182/blood-2021-151738
Published: 2021
Journal Articles

Use of High Dose Cytarabine (HiDAC) for Post-Remission or Re-Induction Therapy Is Safe and Effective in Select Older AML Patients

Jillian Lykon, Ellen Madarang, Nina Nguyen, Wenhui Li, Sunil G. Iyer, Michele Stanchina, Terrence Bradley, Justin Taylor, Namrata Sonia Chandhok, Mikkael A. Sekeres, Justin Watts
Journal: Blood
Blood (2021) 138 (Supplement 1): 4422.
https://doi.org/10.1182/blood-2021-153143
Published: 2021