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Journal Articles

Impaired Early Spliceosome Complex Assembly Underlies Gene Body Elongation Transcription Defect in SF3B1K700E

Prajwal Boddu, Abhishek Gupta, Rahul Roy, barbara De La Pena Avalos, Anne Olazabal Herrero, Joshua Zimmer, Matthew Simon, Namrata Sonia Chandhok, Darren King, Nils Neuenkirchen, Elois Dray, Haifan Lin, Gary Kupfer, Amit Verma, Karla Neugebauer, Manoj Pillai
Journal: Blood
Blood (2023) 142 (Supplement 1): 714.
https://doi.org/10.1182/blood-2023-187303
Published: 2023
Journal Articles

U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies

Giulia Biancon, Poorval Joshi, Joshua T Zimmer, Torben Hunck, Yimeng Gao, Mark D Lessard, Edward Courchaine, Andrew ES Barentine, Martin Machyna, Valentina Botti, Ashley Qin, Rana Gbyli, Amisha Patel, Yuanbin Song, Lea Kiefer, Gabriella Viero, Nils Neuenkirchen, Haifan Lin, Joerg Bewersdorf, Matthew D Simon, Karla M Neugebauer, Toma Tebaldi, Stephanie Halene
Journal: Blood
Blood (2021) 138 (Supplement 1): 321.
https://doi.org/10.1182/blood-2021-149618
Published: 2021
Journal Articles

High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies

Giulia Biancon, PhD, Poorval Joshi, PhD, Torben Hunck, Josh Zimmer, MS, Yimeng Gao, PhD, Martin Machyna, PhD, Valentina Botti, PhD, Ashley Qin, Gabriella Viero, PhD, Nils Neuenkirchen, PhD, Ashley Taylor, Rana Gbyli, MS, Amisha Patel, MS, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Haifan Lin, PhD, Matthew D Simon, PhD, Karla M Neugebauer, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-142854
Published: 2020
Journal Articles

U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex

Giulia Biancon, PhD, Poorval Joshi, PhD, Torben Hunck, Yimeng Gao, PhD, Valentina Botti, PhD, Ashley Qin, Mukhtar Sadykov, MD, Xiaman Wang, MD PhD, Gabriella Viero, PhD, Nils Neuenkirchen, PhD, Ashley Taylor, Jane Huang, BS, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Haifan Lin, PhD, Manoj M Pillai, MD, Clara L Kielkopf, PhD, Karla M Neugebauer, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1230.
https://doi.org/10.1182/blood-2019-130759
Published: 2019