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Journal Articles

U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies

Giulia Biancon, Poorval Joshi, Joshua T Zimmer, Torben Hunck, Yimeng Gao, Mark D Lessard, Edward Courchaine, Andrew ES Barentine, Martin Machyna, Valentina Botti, Ashley Qin, Rana Gbyli, Amisha Patel, Yuanbin Song, Lea Kiefer, Gabriella Viero, Nils Neuenkirchen, Haifan Lin, Joerg Bewersdorf, Matthew D Simon, Karla M Neugebauer, Toma Tebaldi, Stephanie Halene
Journal: Blood
Blood (2021) 138 (Supplement 1): 321.
https://doi.org/10.1182/blood-2021-149618
Published: 2021
Journal Articles

ALKBH5 Modulates Hematopoietic Stem and Progenitor Cell Energy Metabolism through m 6 a Modification-Mediated RNA Stability

Yimeng Gao, Joshua T Zimmer, Radovan Vasic, Chengyang Liu, Rana Gbyli, Shu-Jian Zheng, Amisha Patel, Wei LIU, Raman Nelakanti, Yuanbin Song, Giulia Biancon, Andrew Xiao, Sarah Slavoff, Matthew D Simon, Richard Flavell, Toma Tebaldi, Hua-Bing Li, Stephanie Halene
Journal: Blood
Blood (2021) 138 (Supplement 1): 298.
https://doi.org/10.1182/blood-2021-146049
Published: 2021
Journal Articles

Compromised Host Stem Cell Competitiveness Affords Fanconi Stem Cell Engraftment in C-Kit Mutant Humanized Mice

Wei LIU, Yuanbin Song, Rana Gbyli, Esen Sefik, Giulia Biancon, Yimeng Gao, William Philbrick, Amisha Patel, Toma Tebaldi, Grzegorz Nalepa, Gary M. Kupfer, Richard Flavell, Stephanie Halene
Journal: Blood
Blood (2021) 138 (Supplement 1): 1119.
https://doi.org/10.1182/blood-2021-153777
Published: 2021
Journal Articles

High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies

Giulia Biancon, PhD, Poorval Joshi, PhD, Torben Hunck, Josh Zimmer, MS, Yimeng Gao, PhD, Martin Machyna, PhD, Valentina Botti, PhD, Ashley Qin, Gabriella Viero, PhD, Nils Neuenkirchen, PhD, Ashley Taylor, Rana Gbyli, MS, Amisha Patel, MS, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Haifan Lin, PhD, Matthew D Simon, PhD, Karla M Neugebauer, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-142854
Published: 2020
Journal Articles

Reconstruction of Sickle Cell Disease with Circulating Sickling Red Blood Cells in Novel Humanized Cytokines and Liver Mistrg Mice

Yuanbin Song, MD, Rana Gbyli, MS, Liang Shan, PhD, Wei Liu, PhD, Yimeng Gao, PhD, Amisha Patel, MS, Xiaoying Fu, MD, Xiaman Wang, MD, Mina L. Xu, MD, Ashley Qin, Emanuela Bruscia, MD, Toma Tebaldi, PhD, Giulia Biancon, PhD, Padmavathi Mamillapalli, BS, David Urbonas, David Gonzales, MS, Diane S. Krause, MD PhD, Jonathan Alderman, PhD, Richard Flavell, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-141603
Published: 2020
Journal Articles

Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure

Yimeng Gao, PhD, Radovan Vasic, MD, Yuanbin Song, MD, Rhea Teng, B.Sc., Rana Gbyli, MS, Giulia Biancon, PhD, Raman Nelakanti, B.Sc., Eriko Kudo, B.Sc., Wei Liu, PhD, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Poorval Joshi, PhD, Burak Dura, PhD, Veronica Lee, Gabriella Viero, PhD, Akiko Iwasaki, PhD, Rong Fan, PhD, Andrew Xiao, PhD, Richard Flavell, PhD, Hua-Bing Li, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 450.
https://doi.org/10.1182/blood-2019-130442
Published: 2019
Journal Articles

In Vivo reconstruction of Human Erythropoiesis with Circulating Mature Human RBCs in Humanized Liver Mistrg Mice

Yuanbin Song, MD, Liang Shan, PhD, Rana Gbyli, MS, Wei Liu, PhD, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Ashley Qin, Amisha Patel, MS, Yimeng Gao, PhD, Toma Tebaldi, PhD, Giulia Biancon, PhD, David Urbonas, Jonathan Alderman, PhD, Stephanie Halene, MD, Richard Flavell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 338.
https://doi.org/10.1182/blood-2019-130701
Published: 2019
Journal Articles

PARP Inhibitors Are Effective in IDH1/2 Mutant MDS and AML Resistant to Targeted IDH Inhibitors

Rana Gbyli, MS, Yuanbin Song, MD, Wei Liu, PhD, Yimeng Gao, PhD, Namrata S Chandhok, MD, Xiaoying Fu, MD, Xiaman Wang, MD PhD, Amisha Patel, MS, Ranjini Sundaram, PhD, Toma Tebaldi, PhD, Giulia Biancon, PhD, Anastasia Ardasheva, BS, Ashley Qin, Mukhtar Sadykov, MD, Padmavathi Mamillapalli, BS, Richard Flavell, PhD, Thomas Prebet, MD PhD, Ranjit Bindra, MD PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4222.
https://doi.org/10.1182/blood-2019-130814
Published: 2019
Journal Articles

Variable Response to BCL2 Inhibition in MDS Is Enhanced across MDS Subtypes with Synergistic Combination of BCL2+MCL1 Inhibition

Melissa A. Fischer, MSc, PhD, Maria Arrate, MSc, Merrida A Childress, PhD, Brianna N Smith, MD MS, Yuanbin Song, MD, Rana Gbyli, MS, Thomas Stricker, MD PhD, Stephanie Halene, MD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2982.
https://doi.org/10.1182/blood-2019-126578
Published: 2019