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Gary M. Kupfer
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Journal Articles

Complex Formation between FANCD2 and the Splicing Factor SRSF1 Helps Prevent R-Loop Accumulation through mRNA Export Regulation

Anne Olazabal Herrero, Fengshan Liang, Arijit Dutta, Yuxin Huang, Zhuobin Liang, Abhishek K Gupta, Li Lan, Manoj M Pillai, Patrick Sung, Gary M. Kupfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 5828–5829.
https://doi.org/10.1182/blood-2022-166798
Published: 2022
Journal Articles

Fanci-FANCD2 Promotes Genome Stability and DNA Repair By Down-Regulating BLM Helicase Activity

Fengshan Liang, Arvindhan Nagarajan, Manoj M Pillai, Patrick Sung, Gary M. Kupfer
Journal: Blood
Blood (2021) 138 (Supplement 1): 1113.
https://doi.org/10.1182/blood-2021-152218
Published: 2021
Journal Articles

Compromised Host Stem Cell Competitiveness Affords Fanconi Stem Cell Engraftment in C-Kit Mutant Humanized Mice

Wei LIU, Yuanbin Song, Rana Gbyli, Esen Sefik, Giulia Biancon, Yimeng Gao, William Philbrick, Amisha Patel, Toma Tebaldi, Grzegorz Nalepa, Gary M. Kupfer, Richard Flavell, Stephanie Halene
Journal: Blood
Blood (2021) 138 (Supplement 1): 1119.
https://doi.org/10.1182/blood-2021-153777
Published: 2021
Journal Articles

Rare disease + lots of sequencing = mechanism?

Gary M. Kupfer
Journal: Blood
Blood (2021) 137 (14): 1849–1850.
https://doi.org/10.1182/blood.2020010384
Published: 2021
Journal Articles

Novel Fluorescent Timer Tool Enables Characterization of Erythropoietic Differentiation Based on Differential Cell Cycling Speeds

Susree Modepalli, PhD, Anna Eastman, PhD, Chloe Shaw, Shangqin Guo, PhD, Shilpa M. Hattangadi, MD, Gary M. Kupfer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-141666
Published: 2020
Journal Articles

Binding of FANCD2 to SRSF1 Splicing Factor Prevents Genomic Instability through R Loop Regulation

Anne Olazabal-Herrero, PhD, Allison M. Green, Xiaoyong Chen, Patrick Sung, PhD, Manoj M Pillai, MD, Gary M. Kupfer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19.
https://doi.org/10.1182/blood-2020-141369
Published: 2020
Journal Articles

UAF1 DNA Binding Activity Is Critical for RAD51-Mediated Homologous DNA Pairing

Fengshan Liang, PhD, Adam S Miller, PhD, Carolilne Tang, Patrick Sung, PhD, Gary M. Kupfer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2497.
https://doi.org/10.1182/blood-2019-130435
Published: 2019
Journal Articles

FANCI-FANCD2 Binds RNA, Which Stimulates Its Monoubiquitination

Zhuobin Liang, PhD, Yaqun Teng, PhD, Jingchun Liu, MD, Simonne Longerich, PhD, Xiaoyong Chen, Allison M. Green, PhD, Natalie Collins, MD PhD, Li Lan, MD PhD, Patrick Sung, PhD, Gary M. Kupfer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 645.
https://doi.org/10.1182/blood-2018-99-118863
Published: 2018
Journal Articles

Endosome trafficking: blood and more

Clinical Trials & Observations
Gary M. Kupfer
Journal: Blood
Blood (2018) 132 (6): 557–558.
https://doi.org/10.1182/blood-2018-06-854968
Published: 2018
Journal Articles

Outcomes of Immunosuppressive Therapy for Pediatric Aplastic Anemia: A North American Pediatric Aplastic Anemia Consortium (NAPAAC) Study

Zora R. Rogers, MD, Taizo Allen Nakano, MD, Timothy S. Olson, MD PhD, Alison A. Bertuch, MD PhD, Anjulika Chawla, MD, Paul Castillo, MD, Winfred Wang, MD, Alfred Gillio, MD, Grzegorz Nalepa, MD PhD, Peter Kurre, MD, Carolyn M. Bennett, MD MSc, Rabi Hanna, MD, Christopher Gamper, Gary M. Kupfer, MD, Jennifer A. Rothman, MD, Jessica Boklan, MD, Alexis A Thompson, MD MPH, Amy E. Geddis, MD, Bertil Glader, MD, James N. Huang, MD, Thomas D. Coates, MD, Michaela Cada, MD FRCPC, FAAP, MPH, Kelly J. Walkovich, MD, Sarita Joshi, MBBS,MD, Adrianna Vlachos, MD, Edie A. Weller, David A. Williams, MD, Akiko Shimamura, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1168.
https://doi.org/10.1182/blood.V130.Suppl_1.1168.1168
Published: 2017
Journal Articles

MCM2-7 and FANCD2 Are Required for RAD51 Function in Homologous Recombination and ICL Repair

Xiaoyong Chen, Fengshan Liang, PhD, Judith Sainz, PhD, Ryan Jensen, PhD, Patrick Sung, PhD, Gary M. Kupfer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1180.
https://doi.org/10.1182/blood.V130.Suppl_1.1180.1180
Published: 2017
Journal Articles

The Role of UAF1 in the Fanconi Anemia Pathway Regulation of Homologous Recombination-Mediated Genome Maintenance

Fengshan Liang, PhD, Simonne Longerich, PhD, Caroline Tang, MD, Olga Buzovestsky, Yong Xiong, PhD, David Maranon, PhD, Claudia Wiese, PhD, Adam Miller, PhD, Patrick Sung, PhD, Gary M. Kupfer, MD
Journal: Blood
Blood (2016) 128 (22): 1041.
https://doi.org/10.1182/blood.V128.22.1041.1041
Published: 2016
Journal Articles

Codanin-1 Binds to Key Erythroid Genes and Its Knockdown Coupled with Ectopic Mutant Expression Recapitulates the Congenital Dyserythropoietic Anemia Type I (CDA I) Phenotype

Linette Bosques, Caroline Tang, MD, Diane Krause, MD PhD, Sherman M. Weissman, MD, Patrick G Gallagher, MD, Mitchell J. Weiss, MD PhD, Hannah Tamary, MD, Gary M. Kupfer, MD
Journal: Blood
Blood (2014) 124 (21): 360.
https://doi.org/10.1182/blood.V124.21.360.360
Published: 2014
Journal Articles

Stress and DNA repair biology of the Fanconi anemia pathway

Simonne Longerich, Jian Li, Yong Xiong, Patrick Sung, Gary M. Kupfer
Journal: Blood
Blood (2014) 124 (18): 2812–2819.
https://doi.org/10.1182/blood-2014-04-526293
Published: 2014
Journal Articles

FANCD2 and RAD51 Regulate PCNA Monoubiquitination and Translesion Synthesis

Gary M. Kupfer, MD, Xiaoyong Chen, PhD
Journal: Blood
Blood (2013) 122 (21): 3712.
https://doi.org/10.1182/blood.V122.21.3712.3712
Published: 2013
Journal Articles

Modeling Congenital Dyserythropoietic Anemia Type I Through Patient-Derived Induced Pluripotent Stem Cells

Orna Steinberg Shemer, MD, MSc, Yu Yao, Gary M. Kupfer, MD, Hannah Tamary, MD, Mitchell J. Weiss, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3196.
https://doi.org/10.1182/blood.V120.21.3196.3196
Published: 2012
Journal Articles

Regulation of PCNA Mono-Ubiqutination by FANCD2 and Rad51 in Response to Hydroxyurea.

Gary M. Kupfer, MD, Xiaoyong Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 2377.
https://doi.org/10.1182/blood.V120.21.2377.2377
Published: 2012
Journal Articles

Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis

Sarah M. Lo, Murim Choi, Jun Liu, Dhanpat Jain, Rolf G. Boot, Wouter W. Kallemeijn, Johannes M. F. G. Aerts, Farzana Pashankar, Gary M. Kupfer, Shrikant Mane, Richard P. Lifton, Pramod K. Mistry
Journal: Blood
Blood (2012) 119 (20): 4731–4740.
https://doi.org/10.1182/blood-2011-10-386862
Published: 2012
Journal Articles

A Role for Splicing Factors and the Transcriptional Machinery in the Pathophysiology of Fanconi Anemia,

Allison M Green, M.Phil., James B Wilson, PhD, Nigel J Jones, PhD, Gary M. Kupfer, MD
Journal: Blood
Blood (2011) 118 (21): 3443.
https://doi.org/10.1182/blood.V118.21.3443.3443
Published: 2011
Journal Articles

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

Stacy A. Williams, Simonne Longerich, Patrick Sung, Cyrus Vaziri, Gary M. Kupfer
Journal: Blood
Blood (2011) 117 (19): 5078–5087.
https://doi.org/10.1182/blood-2010-10-311761
Published: 2011