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Luisa Cimmino
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Journal Articles

Vitamin A Directly Enhances TET2 Activity and Suppresses Clonal Hematopoiesis

John P Brabson, Tiffany Leesang, Yoon Sing Yap, Daniela A Barbieri, Joey Pinzone, Minh Quang Lam, Peter D Lyon, Maria E Figueroa, Namrata S. Chandhok, Felipe Beckedorff, Aristeidis Telonis, Luisa Cimmino
Journal: Blood
Blood (2024) 144 (Supplement 1): 4051.
https://doi.org/10.1182/blood-2024-210278
Published: 2024
Journal Articles

One-Carbon Metabolites Promote Systemic Inflammation, Gut Dysbiosis, and a Myeloid Lineage Differentiation Bias

Peter D Lyon, Luis Nivelo, Byron Fang, Victoria Strippoli, Praveen Singh, Sabita Roy, Alejandro Villarino, Luisa Cimmino
Journal: Blood
Blood (2023) 142 (Supplement 1): 4069.
https://doi.org/10.1182/blood-2023-189726
Published: 2023
Journal Articles

Retinoic Acid and Ascorbate Remodel the Epigenome of Leukemia Cells to Improve Therapeutic Efficacy By Enhancing TET Activity

Tiffany Leesang, Yoon Sing Yap, John P Brabson, Abigail Klimas, Emily L Ahearn, Daniela A Barbieri, Minh Quang Lam, Peter D Lyon, Maria Ken E. Figueroa, Felipe Beckedorff, Luisa Cimmino
Journal: Blood
Blood (2023) 142 (Supplement 1): 5706.
https://doi.org/10.1182/blood-2023-189774
Published: 2023
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Vitamin C Enhances PARPi Efficacy for the Treatment of AML

John P Brabson, Tiffany Leesang, Byron Fang, Jingjing Wang, Victoria Strippoli, Yoon-Sing Yap, Sofia Mohammad, Carolina Bañuelos, Peter Lyon, Sana Chaudhry, Minh Lam, Benjamin G Neel, Stephen Nimer, Ramiro E Verdun, Daniel Bilbao, Maria E. Figueroa, Luisa Cimmino
Journal: Blood
Blood (2021) 138 (Supplement 1): 1168.
https://doi.org/10.1182/blood-2021-153884
Published: 2021
Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 561.
https://doi.org/10.1182/blood-2019-130507
Published: 2019
Journal Articles

The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia

Mark D McKenzie, PhD, Margherita Ghisi, PhD, Luisa Cimmino, PhD, Michael Erlichster, Ethan P Oxley, Cynthia Liu, Matthew T Witkowski, PhD, Grace Liu, PhD, Aleksandar Dakic, PhD, Emilia Simankowicz, Ladina DiRago, Donald Metcalf, MD, Stephen L Nutt, PhD, Meaghan Wall, MBBS, PhD FRACP, FRCPA, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2016) 128 (22): 3930.
https://doi.org/10.1182/blood.V128.22.3930.3930
Published: 2016
Journal Articles

miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a

Wenhuo Hu, James Dooley, Stephen S. Chung, Dhruva Chandramohan, Luisa Cimmino, Siddhartha Mukherjee, Christopher E. Mason, Bart de Strooper, Adrian Liston, Christopher Y. Park
Journal: Blood
Blood (2015) 125 (14): 2206–2216.
https://doi.org/10.1182/blood-2014-06-585273
Published: 2015
Includes: Supplemental data
Journal Articles

Reversible Tumor Suppression By Ikzf1/Ikaros in Mouse Models of BCR-ABL1+ B-ALL

Matthew T Witkowski, Yifang Hu, Luisa Cimmino, PhD, Mark D McKenzie, PhD, Grace J Liu, Gordon K Smyth, PhD, Ross A Dickins, PhD
Journal: Blood
Blood (2014) 124 (21): 288.
https://doi.org/10.1182/blood.V124.21.288.288
Published: 2014
Journal Articles

MiR-29a is Essential in Leukemic Transformation and Maintaining Hematopoietic Stem Cell Self-Renewal

Wenhuo Hu, PhD, James Dooley, PhD, Luisa Cimmino, PhD, Adrian Liston, PhD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4792.
https://doi.org/10.1182/blood.V124.21.4792.4792
Published: 2014
Journal Articles

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Alan H. Shih, MD PhD, Yanwen Jiang, PhD, Kaitlyn Shank, Suveg Pandey, Agnes Viale, PhD, Yongming Sun, PhD, Nicholas Socci, PhD, Alexander Robertson, PhD, Elisa de Stanchina, PhD, Todd Hricik, Franck Rapaport, PhD, Brittany Woods, Luisa Cimmino, PhD, Laura Barreyro, M.Sc., Ulrich Steidl, MD PhD, Iannis Aifantis, PhD, Ari Melnick, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 476.
https://doi.org/10.1182/blood.V122.21.476.476
Published: 2013
Journal Articles

Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1.

Mark D McKenzie, Luisa Cimmino, Yifang Hu, Ladina Di Rago, Sandra Mifsud, Donald Metcalf, Gordon K Smyth, Ross Dickins
Journal: Blood
Blood (2012) 120 (21): 2432.
https://doi.org/10.1182/blood.V120.21.2432.2432
Published: 2012
Journal Articles

RNAi Screening Identifies A Novel Role for A-Kinase Anchoring Protein 12 (AKAP12) in B Cell Development and Function

Mutlu Kartal-Kaess, Luisa Cimmino, Simona Infantino, Mehmet Yabas, Jian-Guo Zhang, Laura Tuohey, Irwin H. Gelman, John D. Scott, Stephen L. Nutt, Anselm Enders, David Tarlinton, Ross A Dickins
Journal: Blood
Blood (2012) 120 (21): 855.
https://doi.org/10.1182/blood.V120.21.855.855
Published: 2012