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Journal Articles

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Irina Pleines, Marion Lebois, Pradnya Gangatirkar, Amanda E. Au, Rachael M. Lane, Katya J. Henley, Maria Kauppi, Jason Corbin, Ping Cannon, Jonathan Bernardini, Imala Alwis, Kate E. Jarman, Sarah Ellis, Donald Metcalf, Shaun P. Jackson, Simone M. Schoenwaelder, Benjamin T. Kile, Emma C. Josefsson

Blood (2018) 132 (2): 197–209.

https://doi.org/10.1182/blood-2017-11-816355

Published: 2018

Includes: Supplemental data

Journal Articles

The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia

Mark D McKenzie, PhD, Margherita Ghisi, PhD, Luisa Cimmino, PhD, Michael Erlichster, Ethan P Oxley, Cynthia Liu, Matthew T Witkowski, PhD, Grace Liu, PhD, Aleksandar Dakic, PhD, Emilia Simankowicz, Ladina DiRago, Donald Metcalf, MD, Stephen L Nutt, PhD, Meaghan Wall, MBBS, PhD FRACP, FRCPA, Matthew E Ritchie, PhD, Johannes Zuber, MD PhD, Ross A Dickins, PhD

Blood (2016) 128 (22): 3930.

https://doi.org/10.1182/blood.V128.22.3930.3930

Published: 2016

Journal Articles

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells

Bilal N. Sheikh, Yuqing Yang, Jaring Schreuder, Susan K. Nilsson, Rebecca Bilardi, Sebastian Carotta, Helen M. McRae, Donald Metcalf, Anne K. Voss, Tim Thomas

Blood (2016) 128 (19): 2307–2318.

https://doi.org/10.1182/blood-2015-10-676072

Published: 2016

Includes: Supplemental data

Journal Articles

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

Stanley C. W. Lee, Sarah Miller, Craig Hyland, Maria Kauppi, Marion Lebois, Ladina Di Rago, Donald Metcalf, Sarah A. Kinkel, Emma C. Josefsson, Marnie E. Blewitt, Ian J. Majewski, Warren S. Alexander

Blood (2015) 126 (2): 167–175.

https://doi.org/10.1182/blood-2014-12-615898

Published: 2015

Includes: Supplemental data

Journal Articles

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

W. Wei-Lynn Wong, James E. Vince, Najoua Lalaoui, Kate E. Lawlor, Diep Chau, Aleksandra Bankovacki, Holly Anderton, Donald Metcalf, Lorraine O’Reilly, Philipp J. Jost, James M. Murphy, Warren S. Alexander, Andreas Strasser, David L. Vaux, John Silke

Blood (2014) 123 (16): 2562–2572.

https://doi.org/10.1182/blood-2013-06-510743

Published: 2014

Includes: Supplemental data

Journal Articles

Necroptotic Death Of RIPK1-Deficient HSC Compromises Hematopoiesis

Ben A Croker, O'Donnell A Joanne, Donald Metcalf, Rickard James, Joseph Evans, Seth L. Masters, Andrew W. Roberts, MBBS, PhD, Motti Gerlic, John Silke

Blood (2013) 122 (21): 218.

https://doi.org/10.1182/blood.V122.21.218.218

Published: 2013

Journal Articles

Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1.

Mark D McKenzie, Luisa Cimmino, Yifang Hu, Ladina Di Rago, Sandra Mifsud, Donald Metcalf, Gordon K Smyth, Ross Dickins

Blood (2012) 120 (21): 2432.

https://doi.org/10.1182/blood.V120.21.2432.2432

Published: 2012

Journal Articles

Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia

Catherine L Carmichael, PhD, Donald Metcalf, Katya J. Henley, Elizabeth A Kruse, PhD, Ladina Di Rago, Sandra Mifsud, Jian Zhong Tang, PhD, Warren S. Alexander, Benjamin T. Kile

Blood (2012) 120 (21): 1283.

https://doi.org/10.1182/blood.V120.21.1283.1283

Published: 2012

Journal Articles

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Emma C. Josefsson, Deborah L. Burnett, Marlyse A. Debrincat, Katya J. Henley, Rachael M. Lane, Marion Lebois, Lorraine A. O'Reilly, Marc Pellegrini, Simon P. Preston, Ben A. Croker, Donald Metcalf, Andreas Strasser, Benjamin T. Kile

Blood (2012) 120 (21): 389.

https://doi.org/10.1182/blood.V120.21.389.389

Published: 2012

Journal Articles

Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells

Seth L. Masters, Mordechay Gerlic, Donald Metcalf, Simon P. Preston, Marc Pellegrini, Joanne A. O'Donnell, Kate McArthur, Tracey M. Baldwin, Stephane Chevrier, Cameron J. Nowell, Louise H. Cengia, Katya J. Henley, Janelle E. Collinge, Daniel L. Kastner, Lionel Feigenbaum, Douglas J. Hilton, Warren S. Alexander, Ben A. Croker, Benjamin T. Kile

Blood (2012) 120 (21): 1213.

https://doi.org/10.1182/blood.V120.21.1213.1213

Published: 2012

Journal Articles

Mcl-1 and Bcl-x L coordinately regulate megakaryocyte survival

Marlyse A. Debrincat, Emma C. Josefsson, Chloé James, Katya J. Henley, Sarah Ellis, Marion Lebois, Kelly L. Betterman, Rachael M. Lane, Kelly L. Rogers, Michael J. White, Andrew W. Roberts, Natasha L. Harvey, Donald Metcalf, Benjamin T. Kile

Blood (2012) 119 (24): 5850–5858.

https://doi.org/10.1182/blood-2011-12-398834

Published: 2012

Journal Articles

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice

Ashley P. Ng, Stephen J. Loughran, Donald Metcalf, Craig D. Hyland, Carolyn A. de Graaf, Yifang Hu, Gordon K. Smyth, Douglas J. Hilton, Benjamin T. Kile, Warren S. Alexander

Blood (2011) 118 (9): 2454–2461.

https://doi.org/10.1182/blood-2011-03-344739

Published: 2011

Includes: Supplemental data

Journal Articles

Megakaryocytes Possess a Functional Intrinsic Apoptosis Pathway That Must Be Restrained In Order to Survive and Produce Platelets

Emma C Josefsson, Chloé James, Katya J Henley, Marlyse A Debrincat, Kelly L Rogers, Mark R Dowling, Michael J White, Elizabeth A Kruse, Sarah Ellis, Paquita Nurden, Cassandra J Vandenberg, Kylie D Mason, A O'Reilly Lorraine, Donald Metcalf, Andrew W Roberts, David CS Huang, Benjamin T Kile

Blood (2010) 116 (21): 550.

https://doi.org/10.1182/blood.V116.21.550.550

Published: 2010

Journal Articles

Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance

Kirsteen J. Campbell, Mary L. Bath, Marian L. Turner, Cassandra J. Vandenberg, Philippe Bouillet, Donald Metcalf, Clare L. Scott, Suzanne Cory

Blood (2010) 116 (17): 3197–3207.

https://doi.org/10.1182/blood-2010-04-281071

Published: 2010

Includes: Supplemental data

Journal Articles

Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome

Ashley P. Ng, Craig D. Hyland, Donald Metcalf, Catherine L. Carmichael, Stephen J. Loughran, Ladina Di Rago, Benjamin T. Kile, Warren S. Alexander

Blood (2010) 115 (19): 3966–3969.

https://doi.org/10.1182/blood-2009-09-242107

Published: 2010

Includes: Supplemental data

Journal Articles

Blimp1 is limiting for transformation in a mouse plasmacytoma model

Kathy D'Costa, Dianne Emslie, Donald Metcalf, Gordon K. Smyth, Alexander Karnowski, Axel Kallies, Stephen L. Nutt, Lynn M. Corcoran

Blood (2009) 113 (23): 5911–5919.

https://doi.org/10.1182/blood-2008-08-172866

Published: 2009

Includes: Supplemental data

Journal Articles

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

Catherine L. Carmichael, Ian J. Majewski, Warren S. Alexander, Donald Metcalf, Douglas J. Hilton, Chelsee A. Hewitt, Hamish S. Scott

Blood (2009) 113 (9): 1929–1937.

https://doi.org/10.1182/blood-2008-06-161422

Published: 2009

Includes: Supplemental data

Journal Articles

A key role for G-CSF–induced neutrophil production and trafficking during inflammatory arthritis

Jo L. Eyles, Michael J. Hickey, M. Ursula Norman, Ben A. Croker, Andrew W. Roberts, Sarah F. Drake, Will G. James, Donald Metcalf, Ian K. Campbell, Ian P. Wicks

Blood (2008) 112 (13): 5193–5201.

https://doi.org/10.1182/blood-2008-02-139535

Published: 2008

Includes: Multimedia, Supplemental data

Journal Articles

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl −/− mice

Maria Kauppi, James M. Murphy, Carolyn A. de Graaf, Craig D. Hyland, Kylie T. Greig, Donald Metcalf, Adrienne A. Hilton, Nicos A. Nicola, Benjamin T. Kile, Douglas J. Hilton, Warren S. Alexander

Blood (2008) 112 (8): 3148–3153.

https://doi.org/10.1182/blood-2007-10-119677

Published: 2008

Journal Articles

AGM: maternity ward or finishing school?

Donald Metcalf

Blood (2008) 111 (7): 3305–3306.

https://doi.org/10.1182/blood-2007-11-124412

Published: 2008

NARROW

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

The Transcription Factor PU.1 Controls a Reversible Differentiation Program in Acute Myeloid Leukemia

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

Necroptotic Death Of RIPK1-Deficient HSC Compromises Hematopoiesis

Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1.

Hematopoietic Overexpression of the ETS Family Transcription Factor Erg, or the Oncogenic Fusion Protein TLS-ERG, Induces Erythro-Megakaryocytic Leukemia

Platelet Production Occurs Independently of Both the Intrinsic and Extrinsic Apoptosis Pathways

Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells

Mcl-1 and Bcl-x L coordinately regulate megakaryocyte survival

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice

Megakaryocytes Possess a Functional Intrinsic Apoptosis Pathway That Must Be Restrained In Order to Survive and Produce Platelets

Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance

Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome

Blimp1 is limiting for transformation in a mouse plasmacytoma model

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

A key role for G-CSF–induced neutrophil production and trafficking during inflammatory arthritis

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl −/− mice

AGM: maternity ward or finishing school?

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American Society of Hematology

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ASH Publications

American Society of Hematology

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