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Michael J. White
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Journal Articles

Mcl-1 and Bcl-x L coordinately regulate megakaryocyte survival

Marlyse A. Debrincat, Emma C. Josefsson, Chloé James, Katya J. Henley, Sarah Ellis, Marion Lebois, Kelly L. Betterman, Rachael M. Lane, Kelly L. Rogers, Michael J. White, Andrew W. Roberts, Natasha L. Harvey, Donald Metcalf, Benjamin T. Kile
Journal: Blood
Blood (2012) 119 (24): 5850–5858.
https://doi.org/10.1182/blood-2011-12-398834
Published: 2012
Journal Articles

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

Michael J. White, Simone M. Schoenwaelder, Emma C. Josefsson, Kate E. Jarman, Katya J. Henley, Chloé James, Marlyse A. Debrincat, Shaun P. Jackson, David C. S. Huang, Benjamin T. Kile
Journal: Blood
Blood (2012) 119 (18): 4283–4290.
https://doi.org/10.1182/blood-2011-11-394858
Published: 2012
Includes: Supplemental data
Journal Articles

The Effect of Eltrombopag on Platelet Resistance to Apoptosis: The Role of the Bcl-Xl Pathway

W. Beau Mitchell, MD, Michele N Edison, BS, Mariana P Pinheiro, MD, Nayla Boulad, BA, Bethan Psaila, MD, Marissa Karpoff, BS, Kaplan David, MD, Ph.D., Benjamin T. Kile, PhD, Michael J White, Emma C Josephson, James B Bussel, MD
Journal: Blood
Blood (2011) 118 (21): 1158.
https://doi.org/10.1182/blood.V118.21.1158.1158
Published: 2011
Journal Articles

Bcl-x L –inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Simone M. Schoenwaelder, Kate E. Jarman, Elizabeth E. Gardiner, My Hua, Jianlin Qiao, Michael J. White, Emma C. Josefsson, Imala Alwis, Akiko Ono, Abbey Willcox, Robert K. Andrews, Kylie D. Mason, Hatem H. Salem, David C. S. Huang, Benjamin T. Kile, Andrew W. Roberts, Shaun P. Jackson
Journal: Blood
Blood (2011) 118 (6): 1663–1674.
https://doi.org/10.1182/blood-2011-04-347849
Published: 2011
Includes: Supplemental data
Journal Articles

Megakaryocytes Possess a Functional Intrinsic Apoptosis Pathway That Must Be Restrained In Order to Survive and Produce Platelets

Emma C Josefsson, Chloé James, Katya J Henley, Marlyse A Debrincat, Kelly L Rogers, Mark R Dowling, Michael J White, Elizabeth A Kruse, Sarah Ellis, Paquita Nurden, Cassandra J Vandenberg, Kylie D Mason, A O'Reilly Lorraine, Donald Metcalf, Andrew W Roberts, David CS Huang, Benjamin T Kile
Journal: Blood
Blood (2010) 116 (21): 550.
https://doi.org/10.1182/blood.V116.21.550.550
Published: 2010
Journal Articles

The Effect of Eltrombopag on Human Platelet Resistance to Apoptosis: The Role of the Bcl-Xl Pathway

W. Beau Mitchell, MD, Michele N Edison, BS, Mariana P Pinheiro, MD, Nayla Boulad, BA, Bethan Psaila, MD, PhD, Marissa Karpoff, BS, David Kaplan, MD, Benjamin T Kile, PhD, Michael J White, Emma C Josefsson, James B. Bussel, MD
Journal: Blood
Blood (2010) 116 (21): 2520.
https://doi.org/10.1182/blood.V116.21.2520.2520
Published: 2010
Journal Articles

Deletion of Bcl-X in the Megakaryocyte Compartment Results in Profound Thrombocytopenia Caused by Impaired Platelet Production and Survival.

Chloé James, MD, PhD, Emma C. Josefsson, PhD, Michael J. White, Katya J. Henley, Benjamin T. Kile, PhD
Journal: Blood
Blood (2009) 114 (22): 1495.
https://doi.org/10.1182/blood.V114.22.1495.1495
Published: 2009
Journal Articles

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

Brief Report
Simone M. Schoenwaelder, Yuping Yuan, Emma C. Josefsson, Michael J. White, Yu Yao, Kylie D. Mason, Lorraine A. O'Reilly, Katya J. Henley, Akiko Ono, Sarah Hsiao, Abbey Willcox, Andrew W. Roberts, David C. S. Huang, Hatem H. Salem, Benjamin T. Kile, Shaun P. Jackson
Journal: Blood
Blood (2009) 114 (3): 663–666.
https://doi.org/10.1182/blood-2009-01-200345
Published: 2009
Includes: Supplemental data