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Naser Ansari-Pour
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Journal Articles

A Novel Segmentation-Based Purity-Informed Approach Accurately Detects Total Copy Number and Its Subclonal Fraction in Myeloma Targeted Panel Sequencing Data

Naser Ansari-Pour, Mohammad Kazeroun, Seyed Alireza Hasheminasab, Emma J Lyon, Bethan Hudson-Lund, Evie Fitzsimons, Gaurav Agarwal, Kara-Louise Royle, Matthew W. Jenner, Martin F Kaiser, Karthik Ramasamy, Kwee Yong, Eileen M Boyle, Sarah Gooding, Angela Hamblin, Anjan Thakurta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1909.
https://doi.org/10.1182/blood-2024-207973
Published: 2024
Journal Articles

Risk Assignment Using the Myeloma Genome Project Panel: A Comparison to Standard of Care Genetic Testing within the UK-MRA RADAR Trial

Sarah Gooding, Kara-Louise Royle, Mohammad Kazeroun, Robert Cicero, Laura Chiecchio, Dipal Mehta, Emma J Lyon, Bethan Hudson-Lund, Jasmin Rahman, Khrystal McBean, Martin F Kaiser, Catherine Olivier, Doina Levinte, Charlotte Kennaway, Dean Smith, Jonathan Sive, Ceri Bygrave, Guy Pratt, Michael A. Chapman, Graham Jackson, Rakesh Popat, Christopher Parrish, Gordon Cook, Angela Hamblin, Naser Ansari-Pour, David A. Cairns, Anjan Thakurta, Karthik Ramasamy, Eileen M Boyle, Kwee Yong, Matthew W. Jenner
Journal: Blood
Blood (2024) 144 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2024-209772
Published: 2024
Journal Articles

Acquisition of 1pLOH-1qGain Is a Frequent Trajectory in Expanding Relapsed/Refractory Myeloma Subclones

Naser Ansari-Pour, Mohammad Kazeroun, Evie Fitzsimons, Selina J Chavda, Alessandro Lagana, Erin Flynt, Udo Oppermann, Karthik Ramasamy, Kwee Yong, Sarah Gooding, Anjan Thakurta
Journal: Blood
Blood (2023) 142 (Supplement 1): 1999.
https://doi.org/10.1182/blood-2023-190584
Published: 2023
Journal Articles

Targeted NGS Panel Guides Risk-Adapted Treatment Intention in Newly Diagnosed Myeloma Patients

Gaurav Agarwal, Mohammad Kazeroun, Mirian Salazar, Khrystal McBean, Lisa Ferguson, Jemma Larham, Jaimal Kothari, Naser Ansari-Pour, Sally Moore, Eileen Boyle, Udo Oppermann, Karthik Ramasamy, Angela Hamblin, Anjan Thakurta, Sarah Gooding
Journal: Blood
Blood (2023) 142 (Supplement 1): 644.
https://doi.org/10.1182/blood-2023-182734
Published: 2023
Journal Articles

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

Naser Ansari-Pour, Mehmet Samur, Erin Flynt, Sarah Gooding, Fadi Towfic, Nicholas Stong, Maria Ortiz Estevez, Konstantinos Mavrommatis, Brian Walker, Gareth Morgan, Nikhil Munshi, Herve Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (6): 620–633.
https://doi.org/10.1182/blood.2022017010
Published: 2023
Includes: Supplemental data
Journal Articles

Dynamics of Clonal Hematopoiesis Inferred By Modelling Deep Bulk Whole-Genome Sequencing Data at a Single Time Point

Naser Ansari-Pour, Verena Körber, Niels Asger Jakobsen, Rachel Moore, Nina Claudino, Marlen Metzner, Batchimeg Usukhbayar, Mirian Angulo Salazar, Simon Newman, Benjamin Kendrick, Adrian Taylor, Rasheed Afinowi-Luitz, Roger Gundle, Bridget Watkins, Kim Wheway, Debra Beazley, Andrew Carr, Paresh Vyas, Thomas Höfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 5753–5754.
https://doi.org/10.1182/blood-2022-166236
Published: 2022
Journal Articles

Genomic Panorama and Clonal Evolutionary Trajectory of Classical Hairy Cell Leukemia

Luz Yurany Moreno Rueda, Dean Bryant, William J Tapper, Nicky Weston-Bell, David C Wedge, Naser Ansari-Pour, Surinder S Sahota
Journal: Blood
Blood (2022) 140 (Supplement 1): 8748–8749.
https://doi.org/10.1182/blood-2022-159812
Published: 2022
Journal Articles

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma

Brief Report
Sarah Gooding, Naser Ansari-Pour, Mohammad Kazeroun, Kubra Karagoz, Ann Polonskaia, Mirian Salazar, Evie Fitzsimons, Korsuk Sirinukunwattana, Selina Chavda, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William Pierceall, Daniel Royston, Kwee Yong, Karthik Ramasamy, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2022) 140 (16): 1816–1821.
https://doi.org/10.1182/blood.2022015909
Published: 2022
Includes: Supplemental data
Journal Articles

A Clinically Validated Targeted Capture Panel to Identify Translocations, Copy Number Abnormalities, and Mutations in Multiple Myeloma

Parvathi Sudha, Aarif Ahsan, Akhil Khera, Mohammad H Kazeroun, Tasneem Kausar, Lin Wang, Mirian Angulo Salazar, Evelyn Fitzsimons, Outi Salminen, Timothy Cody Ashby, Patrick Blaney, Magdalena Czader, Gail Vance, Jon Williams, Mohammad Issam Abu Zaid, Karthik Ramasamy, Kwee Yong, Gareth J. Morgan, Frits van Rhee, Rafat Abonour, Erin Flynt, Naser Ansari-Pour, Sarah Gooding, Anjan Thakurta, Brian A Walker
Journal: Blood
Blood (2021) 138 (Supplement 1): 2676.
https://doi.org/10.1182/blood-2021-148692
Published: 2021
Journal Articles

Loss of COP9 Signalosome Gene-Containing 2q Region Is Associated with Lenalidomide and Pomalidomide Resistance in Myeloma Patients

Sarah Gooding, Naser Ansari-Pour, Mohammad H Kazeroun, Kubra Karagoz, Mirian Angulo Salazar, Evelyn Fitzsimons, Maria Ortiz Estevez, Fadi Towfic, Erin Flynt, William E. Pierceall, Kwee Yong, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2021) 138 (Supplement 1): 458.
https://doi.org/10.1182/blood-2021-150166
Published: 2021
Journal Articles

Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma

Clinical Trials & Observations Brief Report
Sarah Gooding, Naser Ansari-Pour, Fadi Towfic, María Ortiz Estévez, Philip P. Chamberlain, Kao-Tai Tsai, Erin Flynt, Marissa Hirst, Dan Rozelle, Paula Dhiman, Paola Neri, Karthik Ramasamy, Nizar Bahlis, Paresh Vyas, Anjan Thakurta
Journal: Blood
Blood (2021) 137 (2): 232–237.
https://doi.org/10.1182/blood.2020007081
Published: 2021
Includes: Supplemental data
Journal Articles

Genetic and Transcript Changesin Cereblon in IMiD-Treated Myeloma Patients

Sarah Gooding, FRCPath,MRCP,MBBChir, Naser Ansari-Pour, PhD, Fadi Towfic, PhD, Maria Ortiz, Dan Rozelle, PhD, Victoria Zadorozhny, Michael Amatangelo, Erin Flynt, Kao-Tai Tsai, Paola Neri, MD PhD, Nizar Bahlis, MD, Paresh Vyas, MD PhD, Anjan Thakurta
Journal: Blood
Blood (2019) 134 (Supplement_1): 1793.
https://doi.org/10.1182/blood-2019-126828
Published: 2019
Journal Articles

Large-Scale Analysis of Relapsed/Refractory Multiple Myeloma Genome Reveals Increased Prevalence of High-Risk Molecular Features and Oncogenic Drivers

Fadi Towfic, PhD, Naser Ansari-Pour, PhD, Maria Ortiz, Sarah Gooding, MD PhD, Dan Rozelle, PhD, Victoria Zadorozhny, Konstantinos Mavrommatis, PhD, Sneh Lata, PhD, Nicholas Stong, PhD, Sitharthan Kamalakaran, PhD, Kao-Tai Tsai, Erin Flynt, Anjan Thakurta
Journal: Blood
Blood (2019) 134 (Supplement_1): 365.
https://doi.org/10.1182/blood-2019-124939
Published: 2019