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Jonathan Sive
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Journal Articles

Risk Assignment Using the Myeloma Genome Project Panel: A Comparison to Standard of Care Genetic Testing within the UK-MRA RADAR Trial

Sarah Gooding, Kara-Louise Royle, Mohammad Kazeroun, Robert Cicero, Laura Chiecchio, Dipal Mehta, Emma J Lyon, Bethan Hudson-Lund, Jasmin Rahman, Khrystal McBean, Martin F Kaiser, Catherine Olivier, Doina Levinte, Charlotte Kennaway, Dean Smith, Jonathan Sive, Ceri Bygrave, Guy Pratt, Michael A. Chapman, Graham Jackson, Rakesh Popat, Christopher Parrish, Gordon Cook, Angela Hamblin, Naser Ansari-Pour, David A. Cairns, Anjan Thakurta, Karthik Ramasamy, Eileen M Boyle, Kwee Yong, Matthew W. Jenner
Journal: Blood
Blood (2024) 144 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2024-209772
Published: 2024
Journal Articles

The Impact of Continuous Lenalidomide Maintenance Treatment on People Living with Multiple Myeloma - a Single-Centre Qualitative Service Evaluation

Caroline Buck, Francisco Castillo, Elena Bettio, Kwee Yong, Annabel Mcmillan, Lydia Sarah Hui Lee, Xenofon Papanikolaou, Ke Xu, Charalampia Kyriakou, Neil Rabin, Ashutosh D. Wechalekar, Rakesh Popat, Joanne Land, Orla McCourt, Helen Poole, Rachel Tarling, Abigail Fisher, Jonathan Sive
Journal: Blood
Blood (2023) 142 (Supplement 1): 6640.
https://doi.org/10.1182/blood-2023-184914
Published: 2023
Journal Articles

Health-Related Quality of Life (HRQoL) in Patients with Genetic Standard and High-Risk Disease at Trial Entry: A Cross-Sectional Analysis of RADAR (UK-MRA Myeloma XV)

Catherine SY Lecat, Alan Chant, Orla McCourt, David Meads, Robert Cicero, Kara-Louise Royle, Ceri Bygrave, Andrew Chantry, Michael A. Chapman, Gordon Cook, Bryony Dawkins, Mark Drayson, Graham Jackson, Matthew W. Jenner, Martin F. Kaiser, Dipal Mehta, Roger Owen, Rakesh Popat, Christopher Parrish, Guy Pratt, Jonathan Sive, Dean Smith, Ruth M de Tute, Lorna Barnard, Sharon Jackson, Doina Levinte, Catherine Olivier, Karthik Ramasamy, Kwee Yong, David Allan Cairns
Journal: Blood
Blood (2023) 142 (Supplement 1): 4710.
https://doi.org/10.1182/blood-2023-187453
Published: 2023
Journal Articles

Infection Risk and Use of Prophylaxis with Anti-BCMA Bispecific T Cell Engagers and Belantamab Mafodotin for Patients with Relapsed and Refractory Multiple Myeloma

Rakesh Popat, Kathleen Cheok, Amrutha Sridhar, Conor Feely, Catriona Mactier, Annabel Mcmillan, Ashutosh D. Wechalekar, Neil Rabin, Jonathan Sive, Charalampia Kyriakou, Ke Xu, Xenofon Papanikolaou, Shameem Mahmood, Kwee Yong, Lydia Sarah Hui Lee
Journal: Blood
Blood (2023) 142 (Supplement 1): 4702.
https://doi.org/10.1182/blood-2023-182725
Published: 2023
Journal Articles

High Success Rates Utilizing Local Standard of Care Cytogenetic Testing for Risk Stratified Frontline Therapy for Newly Diagnosed Multiple Myeloma: Experience from the Ukmra RADAR Study

Dipal Mehta, Laura Chiecchio, Martin F. Kaiser, Sarah Gooding, Kara-Louise Royle, Doina Levinte, Catherine Olivier, David Allan Cairns, Lorna Barnard, Sharon Jackson, Robert Cicero, Gordon Cook, Michael A. Chapman, Alan Chant, David Meads, Bryony Dawkins, Guy Pratt, Rakesh Popat, Graham Jackson, Ceri Bygrave, Andrew Chantry, Jonathan Sive, Christopher Parrish, Dean Smith, Mark Drayson, Roger Owen, Ruth M de Tute, Karthik Ramasamy, Kwee Yong, Matthew W. Jenner
Journal: Blood
Blood (2023) 142 (Supplement 1): 6715.
https://doi.org/10.1182/blood-2023-188697
Published: 2023
Journal Articles

RADAR Trial: MRD Response Adapted Trial for Newly Diagnosed Transplant Eligible Myeloma Patients

Karthik Ramasamy, David Allan Cairns, Kara-Louise Royle, Robert Cicero, Catherine Olivier, Lorna Barnard, Sharon Jackson, Doina Levinte, Gordon Cook, Alan Chant, David Meads, Bryony Dawkins, Michael A. Chapman, Guy Pratt, Rakesh Popat, Graham Jackson, Ceri Bygrave, Andrew Chantry, Martin F. Kaiser, Jonathan Sive, Christopher Parrish, Dean Smith, Matthew W. Jenner, Mark Drayson, Roger Owen, Ruth M de Tute, Dipal Mehta, Kwee Yong
Journal: Blood
Blood (2023) 142 (Supplement 1): 3390.
https://doi.org/10.1182/blood-2023-188844
Published: 2023
Journal Articles

Risk-Adapted Therapy Directed According to Response (RADAR, UK-MRA Myeloma XV) - Comparing MRD-Guided Treatment Escalation and De-Escalation Strategies in Patients with Newly Diagnosed Myeloma Suitable for Stem Cell Transplantation

Kwee Yong, Kara-Louise Royle, Karthik Ramasamy, Christopher Parrish, Anna Hockaday, Samir Asher, Mark T Drayson, Ruth M. de Tute, Matthew W Jenner, Martin F. Kaiser, Guy Pratt, Jonathan Sive, Ceri Bygrave, Gordon Cook, Rakesh Popat, Dean Smith, Catherine Olivier, Lorna Barnard, Doina Levinte, Bryony Dawkins, Michael A Chapman, Andrew D Chantry, Graham Jackson, Sergio A Quezada, Roger G Owen, David Cairns
Journal: Blood
Blood (2022) 140 (Supplement 1): 1844–1846.
https://doi.org/10.1182/blood-2022-168842
Published: 2022
Journal Articles

Survey of the Relevance of Quality of Life (QoL) Questionnaires (QoLQs) Currently Used to Evaluate Multiple Myeloma (MM) Patients' Qol in Real-World MM Patients and Healthcare Professionals (HCPs)

Sotirios Bristogiannis, Yadanar Lwin, Catherine SY Lecat, Joanne Sowter, Orla McCourt, Emma Dowling, Nuno Correia, Neil K Rabin, Ke Xu, Jonathan Sive, Xenofon Papanikolaou, Rakesh Popat, Lydia Lee, Annabel McMillan, Sosana Delimpasi, Ashutosh D. Wechalekar, Kwee Yong, Charalampia Kyriakou
Journal: Blood
Blood (2022) 140 (Supplement 1): 12506–12507.
https://doi.org/10.1182/blood-2022-167272
Published: 2022
Journal Articles

Impact of Autologous Stem Cell Transplant (ASCT) Versus Consolidation on Health-Related Quality of Life (HRQoL) for Patients with Multiple Myeloma Receiving Carfilzomib Maintenance: Results from the Cardamon Trial

Rakesh Popat, William Wilson, Marquita Camilleri, Karthik Ramasamy, Matthew Streetly, Jonathan Sive, Ceri Bygrave, Reuben Benjamin, Michael A Chapman, Selina J Chavda, Beth Phillips, Maria del Mar Cuadrado, Gavin Pang, Richard Jenner, Tushhar Dadaga, Sumaiya Kamora, Ruth M. de Tute, James Cavenagh, Laura Clifton-Hadley, Roger G Owen, Kwee Yong
Journal: Blood
Blood (2022) 140 (Supplement 1): 10191–10192.
https://doi.org/10.1182/blood-2022-166344
Published: 2022
Journal Articles

PET-CT for Assessment of Multiple Myeloma Disease Burden and Metabolic Response before and after Carfilzomib-Based Induction, Consolidation and Carfilzomib Maintenance Therapy: Data from the UK NCRI Cardamon Study

Ceri A Bygrave, Manil Subesinghe, William Wilson, Rakesh Popat, Karthik Ramasamy, Gavin Pang, Richard Jenner, Sumaiya Kamora, Tushhar Dadaga, Lucy Pike, Matthew Streetly, Marquita Camilleri, Roger G Owen, James Cavenagh, Jonathan Sive, Michael Chapman, Elizabeth H Phillips, Selina J Chavda, Maria del Mar Cuadrado, Reuben Benjamin, Lydia Eccersley, Sally Moore, Lalita Banerjee, Laura Clifton-Hadley, Sally F Barrington, Kwee Yong
Journal: Blood
Blood (2021) 138 (Supplement 1): 2750.
https://doi.org/10.1182/blood-2021-150177
Published: 2021
Journal Articles

Upfront Autologous Stem Cell Transplantation (ASCT) Vs Carfilzomib-Cyclophosphamide-Dexamethasone (KCd) Consolidation in Transplant-Eligible, Newly Diagnosed (NDTE) Multiple Myeloma (MM): Results of the Cardamon Study According to Cytogenetic Risk

Kwee Yong, William Wilson, Marquita Camilleri, Karthik Ramasamy, Matthew Streetly, Jonathan Sive, Ceri A Bygrave, Michael Chapman, Ruth M. de Tute, Selina J Chavda, Elizabeth H Phillips, Maria del Mar Cuadrado, Gavin Pang, Richard Jenner, Tushhar Dadaga, Sumaiya Kamora, James Cavenagh, Laura Clifton-Hadley, Roger G Owen, Rakesh Popat
Journal: Blood
Blood (2021) 138 (Supplement 1): 2911.
https://doi.org/10.1182/blood-2021-147771
Published: 2021
Journal Articles

Serological Response to the BNT162b2 mRNA or Chadox-Ncov-19 COVID-19 Vaccine after First and Second Doses in Plasma Cell Disorder Patients: Influence of Host and Disease Factors

Wei Yee Chan, Lara Howells, William Wilson, Emilie Sanchez, Louise Ainley, Selina J Chavda, Emma Dowling, Nuno Correia, Catherine SY Lecat, Annabel McMillan, Brendan Wisniowski, Shameem Mahmood, Xenofon Papanikolaou, Lydia Lee, Jonathan Sive, Charalampia Kyriakou, Ashutosh D. Wechalekar, Rakesh Popat, Neil K Rabin, Eleni Nastouli, Kwee Yong, Ke Xu
Journal: Blood
Blood (2021) 138 (Supplement 1): 1628.
https://doi.org/10.1182/blood-2021-149027
Published: 2021
Journal Articles

Subsequent Treatments, Responses and Survival in the Real World for Patients with Relapsed Multiple Myeloma Following Treatment with Lenalidomide

Jessica B Taube, MBBChir, Catherine SY Lecat, MBBS, Simon Cheesman, BPharm, Gabriel Wallis, Charalampia Kyriakou, Lydia Lee, Shameem Mahmood, Xenofon Papanikolaou, Christopher Parrish, MB BChir MA MRCP FRCPath PhD, Neil K Rabin, Sajitha Sachchithananthan, Jonathan Sive, MD, Ashutosh D. Wechalekar, Kwee Yong, Gordon Cook, Rakesh Popat
Journal: Blood
Blood (2019) 134 (Supplement_1): 4340.
https://doi.org/10.1182/blood-2019-128266
Published: 2019
Journal Articles

High Rates of Venous and Arterial Thrombotic Events in POEMS Patients: Results from the UK-Based POEMS Registry, Highlighting the Need for Therapeutic Guidelines

Zara Sayar, MD FRCPath, MRCP, Anna Weatherill, Stephen Keddie, Jonathan Sive, MD, Michael P Lunn, Mari Thomas, Shirley D'Sa
Journal: Blood
Blood (2019) 134 (Supplement_1): 714.
https://doi.org/10.1182/blood-2019-125639
Published: 2019
Journal Articles

Efficacy and Safety of Carfilzomib at 56mg/m 2 with Cyclophosphamide and Dexamethasone (K56Cd) in Newly Diagnosed Multiple Myeloma Patients Followed By ASCT or K56Cd Consolidation: Initial Results of the Phase 2 Cardamon Study

Kwee Yong, Rakesh Popat, William Wilson, Gavin Pang, Richard Jenner, Ruth M De Tute, BSc,MSc, Karthik Ramasamy, MBBS MRCP FRCPath PhD, Matthew Streetly, MD, Jamie Cavenagh, MD PhD, Jonathan Sive, MD, Michael Chapman, PhD MRCP, FRCPath, Ceri Bygrave, MD FRCPath, MPhil, Beth Phillips, MBBS, FRCPath, BSc, Selina J Chavda, Andres E. Virchis, FRCP, FRCPath, Reuben Benjamin, FRCPath, MRCP, MBBS, PhD, Sarah Arnott, Fenella Willis, Sandra Hassan, MBBS, MRCP, FRCPath, MDRes), Sally Moore, Laura Clifton-Hadley, PhDBSc, Roger G Owen, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 861.
https://doi.org/10.1182/blood-2019-127992
Published: 2019
Journal Articles

RNA-seq of newly diagnosed patients in the PADIMAC study leads to a bortezomib/lenalidomide decision signature

Michael A. Chapman, Jonathan Sive, John Ambrose, Claire Roddie, Nicholas Counsell, Anna Lach, Mahnaz Abbasian, Rakesh Popat, Jamie D. Cavenagh, Heather Oakervee, Matthew J. Streetly, Stephen Schey, Mickey Koh, Fenella Willis, Andres E. Virchis, Josephine Crowe, Michael F. Quinn, Gordon Cook, Charles R. Crawley, Guy Pratt, Mark Cook, Nivette Braganza, Toyin Adedayo, Paul Smith, Laura Clifton-Hadley, Roger G. Owen, Pieter Sonneveld, Jonathan J. Keats, Javier Herrero, Kwee Yong
Journal: Blood
Blood (2018) 132 (20): 2154–2165.
https://doi.org/10.1182/blood-2018-05-849893
Published: 2018
Includes: Supplemental data
Journal Articles

A Seven Gene Signature to Distinguish Bortezomib- and Lenalidomide-Responsive Myeloma: Rnaseq from the Padimac Study

Michael Chapman, PhD MRCP, FRCPath, Jonathan Sive, John Ambrose, Claire Roddie, PhD MD, Nicholas Counsell, Paul Smith, Nivette Braganza, Toyin Adedayo, Rakesh Popat, MD PhD, James D Cavenagh, Matthew J. Streetly, BMBS, PhD MRCP, FRCPath, Roger G. Owen, MD, Stephen Schey, MBBS, Mickey Koh, MD PhD, Josephine Crowe, Michael F. Quinn, FRCPath, MB, MD MRCP, Shirley D'Sa, MD FRCP, FRCPath, Andres E. Virchis, FRCP, FRCPath, Gordon Cook, PhD, Charles R Crawley, Guy Pratt, MD FRCP, FRCPath, Mark Cook, MBChB,PhD, Laura Clifton-Hadley, PhDBSc, Javier Herrero, PhD, Kwee Yong, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 267.
https://doi.org/10.1182/blood.V130.Suppl_1.267.267
Published: 2017
Journal Articles

Prevalence of TP53 Mutations in Del(17p) Myeloma: Spectrum of Mutations and Effect on Survival

Melody Chin, BSc, MSc, Jonathan Sive, MBBS, Christopher Allen, BSc, Claire Roddie, MD PhD, Selina J Chavda, MBBS BSc MRCP, Dean Smith, MBBS, Rakesh Popat, Ali Rismani, MBBS, Shirley D'Sa, Neil Rabin, Rosemary E. Gale, PhD BSc, Kwee L Yong
Journal: Blood
Blood (2016) 128 (22): 4455.
https://doi.org/10.1182/blood.V128.22.4455.4455
Published: 2016