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Journal Articles

A Self-Supervised Machine Learning Model Can Differentiate MDS from Clinical Mimics Based on Bone Marrow Biopsy Features

Bita Jafarzadeh, Vahid Mehrtash, Hortense Le, Dan Yoon, Nicolas Coudray, Sanam Loghavi, Aristotelis Tsirigos, Christopher Y. Park

Blood (2024) 144 (Supplement 1): 7496.

https://doi.org/10.1182/blood-2024-211667

Published: 2024

Journal Articles

Self-Supervised Learning Based Characterization of Bone Marrow Biopsies for Enhanced Diagnosis of Hematologic Disorders

Dan Yoon, Bita Jafarzadeh, Vahid Mehrtash, Hortense Le, Nicolas Coudray, Aristotelis Tsirigos, Christopher Y. Park

Blood (2024) 144 (Supplement 1): 2234.

https://doi.org/10.1182/blood-2024-210945

Published: 2024

Journal Articles

CRISPR/ Rfx Cas13d Screening Identifies the Long Non-Coding RNA (LncRNA) Nfyc-AS1 As a Molecular Vulnerability in Acute Myeloid Leukemia (AML)

Dimitrios Papaioannou, Giovanni Gambi, Palaniraja Thandapani, Deedra Nicolet, Ziyan Lin, Krzysztof Mrózek, Olha Ivashkiv, Maria Sirenko, Bettina Nadorp, Ann-Kathrin Eisfeld, Aristotelis Tsirigos, Iannis Aifantis

Blood (2024) 144 (Supplement 1): 951.

https://doi.org/10.1182/blood-2024-203707

Published: 2024

Journal Articles

Self-Supervised Learning Model Accurately Diagnoses Hemophagocytic Lymphohistiocytosis from Histology Images

Dan Yoon, Erim Keresteci, Bita Jafarzadeh, Vahid Mehrtash, Hortense Le, Nicolas Coudray, Aristotelis Tsirigos, Christopher Y. Park

Blood (2024) 144 (Supplement 1): 3916.

https://doi.org/10.1182/blood-2024-207980

Published: 2024

Journal Articles

Integrated Genomic Analysis Identifies a Downstream Regulatory Element Oncogenically Activating Hematopoietically Expressed Homeobox ( HHEX ) in ETP-ALL

Utpal P. Davé, Justin Layer, Bernhard Maier, Bryan Venters, Neal Copeland, Nancy Jenkins, Aristotelis Tsirigos, Javier Rodriguez Hernaez, Mircea Ivan

Blood (2023) 142 (Supplement 1): 1403.

https://doi.org/10.1182/blood-2023-182950

Published: 2023

Journal Articles

Single Cell Analysis of Bone Marrow Stromal Cells Shows That a Pro-Inflammatory and Stress Response Together with Polarized Differentiation of Stromal Elements Characterize the Bone Marrow Microenvironment during Multiple Myeloma Development

Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Eileen Boyle, Yubao Wang, Liming Hou, Ola Landgren, Francesco Maura, Aristotelis Tsirigos, Gareth J. Morgan, Faith E. Davies

Blood (2023) 142 (Supplement 1): 332.

https://doi.org/10.1182/blood-2023-182968

Published: 2023

Journal Articles

The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 292.

https://doi.org/10.1182/blood-2023-182967

Published: 2023

Journal Articles

Haplodeficiency of the 9p21 tumor suppressor locus causes myeloid disorders driven by the bone marrow microenvironment

Jue Feng, Pei-Feng Hsu, Eduardo Esteva, Rossella Labella, Yueyang Wang, Alireza Khodadadi-Jamayran, Joseph Pucella, Cynthia Z. Liu, Arnaldo A. Arbini, Aristotelis Tsirigos, Stavroula Kousteni, Boris Reizis

Blood (2023) 142 (5): 460–476.

https://doi.org/10.1182/blood.2022018512

Published: 2023

Includes: Supplemental data

Journal Articles

Structural Heterogeneity of Chromosome 1q Drives Outcome in Newly Diagnoses Myeloma

Blood (2022) 140 (Supplement 1): 4253–4254.

https://doi.org/10.1182/blood-2022-165467

Published: 2022

Journal Articles

The Role of Relapse Specific over-Expression of S100A8/A9 B Leukemic Cells in Promoting Chemoresistance

Clemence Aldebert, Emily Duan, Sylwia Jasinski, Talia H Ostrow, Isaiah Gonzalez, Aristotelis Tsirigos, Elizabeth A. Raetz, Nikki Ann Evensen, William L. Carroll

Blood (2022) 140 (Supplement 1): 6337–6338.

https://doi.org/10.1182/blood-2022-169273

Published: 2022

Journal Articles

Selective STAT3 Degraders Dissect Peripheral T-Cell Lymphomas Vulnerabilities Empowering Personalized Regimens

Blood (2021) 138 (Supplement 1): 865.

https://doi.org/10.1182/blood-2021-153995

Published: 2021

Journal Articles

Multiomic Mapping of Copy Number and Structural Variation on Chromosome 1 (Chr1) Highlights Multiple Recurrent Disease Drivers

Blood (2021) 138 (Supplement 1): 721.

https://doi.org/10.1182/blood-2021-148439

Published: 2021

Journal Articles

Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome

Nevin Yusufova, Matthew R Teater, PhD, Alexey Soshnev, Andreas Kloetgen, Adewola Osunsade, Joseph Conway, Ashley Doane, Arthur Skoultchi, Aristotelis Tsirigos, PhD, Yael David, C. David Allis, PhD, Ethel Cesarman, MD PhD, Ari Melnick, MD

Blood (2019) 134 (Supplement_1): 23.

https://doi.org/10.1182/blood-2019-127774

Published: 2019

Journal Articles

Identification of a Whole Blood Signature for Venous Thromboembolism

Marie Hogan, MD, Hua Zhou, Tenzin Lhakhang, MD, Tessa Jo Barrett, PhD, Deirdre O'Reilly, Nathaniel Smilowitz, MD, Adriana Heguy, PhD, Thomas Maldonado, MD, Aristotelis Tsirigos, PhD, Jeffrey Berger, MD

Blood (2018) 132 (Supplement 1): 3809.

https://doi.org/10.1182/blood-2018-99-110225

Published: 2018

Journal Articles

Genomic and Epigenetic Effects of DNA Methyltransferase Inhibition in Acute Lymphoblastic Leukemia

Shella Saint Fleur-Lominy, MDPhD, Teena Bhatla, MD, Stephen Kelly, MS, Varshini Vasudevaraja, MS, Aristotelis Tsirigos, PhD, William L. Carroll, MD

Blood (2017) 130 (Supplement 1): 2479.

https://doi.org/10.1182/blood.V130.Suppl_1.2479.2479

Published: 2017

Journal Articles

An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia

Panagiotis Ntziachristos, PhD, Aristotelis Tsirigos, Grant Welstead, Thomas Trimarchi, Linda Holmfeldt, PhD, Takashi Satoh, Elisabeth M. Paietta, PhD, Martin S. Tallman, MD, Jacob M. Rowe, MD, Giovanni Tonon, MDPhD, Jared Becksfort, MS, Laurens Kruidenier, Rab K Prinjha, Pieter Van Vlierberghe, Rudolph Jaenisch, PhD, Adolfo A. Ferrando, MD PhD, Charles G. Mullighan, MBBS, MSc, MD, Iannis Aifantis

Blood (2014) 124 (21): 56.

https://doi.org/10.1182/blood.V124.21.56.56

Published: 2014

NARROW

A Self-Supervised Machine Learning Model Can Differentiate MDS from Clinical Mimics Based on Bone Marrow Biopsy Features

Self-Supervised Learning Based Characterization of Bone Marrow Biopsies for Enhanced Diagnosis of Hematologic Disorders

CRISPR/ Rfx Cas13d Screening Identifies the Long Non-Coding RNA (LncRNA) Nfyc-AS1 As a Molecular Vulnerability in Acute Myeloid Leukemia (AML)

Self-Supervised Learning Model Accurately Diagnoses Hemophagocytic Lymphohistiocytosis from Histology Images

Integrated Genomic Analysis Identifies a Downstream Regulatory Element Oncogenically Activating Hematopoietically Expressed Homeobox ( HHEX ) in ETP-ALL

Single Cell Analysis of Bone Marrow Stromal Cells Shows That a Pro-Inflammatory and Stress Response Together with Polarized Differentiation of Stromal Elements Characterize the Bone Marrow Microenvironment during Multiple Myeloma Development

The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia

Haplodeficiency of the 9p21 tumor suppressor locus causes myeloid disorders driven by the bone marrow microenvironment

Structural Heterogeneity of Chromosome 1q Drives Outcome in Newly Diagnoses Myeloma

The Role of Relapse Specific over-Expression of S100A8/A9 B Leukemic Cells in Promoting Chemoresistance

Selective STAT3 Degraders Dissect Peripheral T-Cell Lymphomas Vulnerabilities Empowering Personalized Regimens

Multiomic Mapping of Copy Number and Structural Variation on Chromosome 1 (Chr1) Highlights Multiple Recurrent Disease Drivers

Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome

Identification of a Whole Blood Signature for Venous Thromboembolism

Genomic and Epigenetic Effects of DNA Methyltransferase Inhibition in Acute Lymphoblastic Leukemia

An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia

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American Society of Hematology

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American Society of Hematology

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