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Palaniraja Thandapani
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Journal Articles

Prolyl-tRNA synthetase inhibition disrupts oncogenic translation in T-cell acute lymphoblastic leukemia

Free
Valerio Ciaurro, Abdul Khalique, Priyanshu Srivastava, Yu Zhou, Paul Hauser, N. Connor Payne, Marian Kalocsay, Ralph Mazitschek, Palaniraja Thandapani
Journal: Blood
Blood (2025) 146 (Supplement 1): 6780.
https://doi.org/10.1182/blood-2025-6780
Published: 2025
Journal Articles

CRISPR-Cas9 screen-driven identification of metabolic vulnerabilities reveals synthetic lethality via synergistic targeting of mitochondrial energy pathways and lactate export in oxphos-dependent T-ALL

Free
Natalia Baran, Alessia Lodi, Shraddha Patel, Jose Enriquez Ortiz, Meghan Collins, Priyanka Sharma, Vakul Mohanty, Merve Dede, Ivo Veletic, Cassandra L Ramage, Jun Hyoung Park, Yogesh Dhungana, Anna Skwarska, Yu Zhou, Zhihong Zeng, Connie Weng, Kala Hayes, Gheath Alatrash, Kenneth Dunner, Joseph R Marszalek, Gautam Borthakur, Jiyang Yu, Palaniraja Thandapani, Richard Davis, Benny A Kaipparettu, Ken Chen, Pratip K Bhattacharya, Stefano Tiziani, Marina Konopleva
Journal: Blood
Blood (2025) 146 (Supplement 1): 1538.
https://doi.org/10.1182/blood-2025-1538
Published: 2025
Journal Articles

Venetoclax As a Combination Partner with NAMPT Inhibitor Rpt-1G for T-ALL

Free
John R. Sanchez, II, Daisy Y. Diaz Rohena, Charmelle D. Williams, Valerio Ciaurro, Min Wu, Francis Roushar, Dennise A. De Jesús-Díaz, Gregory Crimmins, Vinay Puduvalli, Francisco Vega, Palaniraja Thandapani, Deepa Sampath
Journal: Blood
Blood (2024) 144 (Supplement 1): 5900.
https://doi.org/10.1182/blood-2024-208190
Published: 2024
Journal Articles

TP53 Gain-of-Function Mutants Display Unique Transcriptional Profiles in Chronic Lymphocytic Leukemia

Free
Charmelle D. Williams, Suresh Satpati, Janani Ravikrishnan, Bailey Slawin, Daisy Y. Diaz Rohena, Palaniraja Thandapani, Kerry A. Rogers, Seema A. Bhat, Kunal Rai, Jennifer A. Woyach, Deepa Sampath
Journal: Blood
Blood (2024) 144 (Supplement 1): 6757.
https://doi.org/10.1182/blood-2024-199814
Published: 2024
Journal Articles

CRISPR/ Rfx Cas13d Screening Identifies the Long Non-Coding RNA (LncRNA) Nfyc-AS1 As a Molecular Vulnerability in Acute Myeloid Leukemia (AML)

Free
Dimitrios Papaioannou, Giovanni Gambi, Palaniraja Thandapani, Deedra Nicolet, Ziyan Lin, Krzysztof Mrózek, Olha Ivashkiv, Maria Sirenko, Bettina Nadorp, Ann-Kathrin Eisfeld, Aristotelis Tsirigos, Iannis Aifantis
Journal: Blood
Blood (2024) 144 (Supplement 1): 951.
https://doi.org/10.1182/blood-2024-203707
Published: 2024
Journal Articles

Targeting Proline Trna Biogenesis for Treatment of T Cell Acute

Free
Valerio Ciaurro, Priyanshu Srivastava, Abdul Khalique, Jared Brottem, N Connor Payne, Ralph Mazitschek, Palaniraja Thandapani
Journal: Blood
Blood (2024) 144 (Supplement 1): 5835.
https://doi.org/10.1182/blood-2024-200359
Published: 2024