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Journal Articles

Somatic Hypermutation in Enhancer Regions Shapes Non-Coding Myeloma Genome, Generating DNA Breaks and Driving Etiology through Mutation and Structural Variation

Patrick Blaney, Brian A. Walker, Aneta Mikulasova, Dylan Gagler, Bachisio Ziccheddu, Benjamin Diamond, Yubao Wang, Liming Hou, Sanxiong Liu, Alexandra Maria Poos, Anthony Cirrincione, Kylee H Maclachlan, Elias K. Mai, Hartmut Goldschmidt, Saad Z Usmani, Marc S. Raab, Niels Weinhold, Ola Landgren, Faith E. Davies, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1401.
https://doi.org/10.1182/blood-2023-190473
Published: 2023
Journal Articles

Single Cell Analysis of Bone Marrow Stromal Cells Shows That a Pro-Inflammatory and Stress Response Together with Polarized Differentiation of Stromal Elements Characterize the Bone Marrow Microenvironment during Multiple Myeloma Development

Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Eileen Boyle, Yubao Wang, Liming Hou, Ola Landgren, Francesco Maura, Aristotelis Tsirigos, Gareth J. Morgan, Faith E. Davies
Journal: Blood
Blood (2023) 142 (Supplement 1): 332.
https://doi.org/10.1182/blood-2023-182968
Published: 2023
Journal Articles

Whole-Genome Sequencing Reveals Distinct Mutational Signatures in Multiple Myeloma Patients with African Ancestry Compared with Those of Non-African Ancestry

Kylee H Maclachlan, Patrick Blaney, Anthony Cirrincione, Timothy R. Chu, Alexandra Maria Poos, Elizabeth E. Brown, Elisabet E. Manasanch, Antje Hoering, Liming Hou, Dylan Gagler, Yubao Wang, Sanxiong Liu, Benjamin Diamond, Bachisio Ziccheddu, Marc S. Raab, Niels Weinhold, Ola Landgren, Nicolas Robine, Faith E. Davies, Alexander Lesokhin, Saad Z Usmani, Francesco Maura, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2023-190882
Published: 2023