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James E Hoffman
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Journal Articles

Tocilizumab Prophylaxis for Patients Treated with Teclistamab: A Single-Center Experience

Andrew Kowalski, Jillian Lorayne Lykon, Benjamin Diamond, David Coffey, Marcella Kaddoura, Francesco Maura, James E. Hoffman, Dickran Kazandjian, Ola Landgren
Journal: Blood
Blood (2023) 142 (Supplement 1): 4709.
https://doi.org/10.1182/blood-2023-187086
Published: 2023
Journal Articles

Patterns of Response to 200 Mg Linvoseltamab in Patients with Relapsed/Refractory Multiple Myeloma: Longer Follow-Up of the Linker-MM1 Study

Sundar Jagannath, Joshua Richter, Madhav V. Dhodapkar, James E. Hoffman, Hans C. Lee, Attaya Suvannasankha, Mansi R. Shah, Suzanne Lentzsch, Jeffrey A. Zonder, Rachid Baz, Joseph J. Maly, Swathi Namburi, Ka Lung Wu, Matthew Pianko, Jing Christine Ye, Rebecca Silbermann, Chang-Ki Min, Marie-Christiane Vekemans, Markus Munder, Ja Min Byun, Joaquín Martínez Lopez, Michelle DeVeaux, Dhruti Chokshi, Anita Boyapati, Anasuya Hazra, Karen Rodriguez Lorenc, Glenn S. Kroog, Yariv Houvras, Naresh Bumma
Journal: Blood
Blood (2023) 142 (Supplement 1): 4746.
https://doi.org/10.1182/blood-2023-177968
Published: 2023
Journal Articles

Health-Related Quality of Life (HRQoL) Among Patients with Triple-Class Exposed Relapsed/Refractory Multiple Myeloma (RRMM) Treated with Linvoseltamab in Linker-MM1: Interim Assessment up to 36 Weeks of Treatment

James E. Hoffman, Naresh Bumma, Joshua Richter, Madhav V. Dhodapkar, Hans C. Lee, Attaya Suvannasankha, Christiane A. Houde, Joseph J. Maly, Mansi R. Shah, Rachid Baz, Swathi Namburi, Ka Lung Wu, Matthew Pianko, Jing Christine Ye, Suzanne Lentzsch, Rebecca Silbermann, Chang-Ki Min, Marie-Christiane Vekemans, Markus Munder, Ja Min Byun, Joaquín Martínez Lopez, Michelle DeVeaux, Cristina Ivanescu, Karen Rodriguez Lorenc, Glenn S. Kroog, Yariv Houvras, Timothy J. Inocencio, Lei Chi, James Harnett, Qiufei Ma, Sundar Jagannath
Journal: Blood
Blood (2023) 142 (Supplement 1): 3359.
https://doi.org/10.1182/blood-2023-179170
Published: 2023
Journal Articles

Selinexor, Venetoclax, and Dexamethasone in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma (SELVEDge Study)

Dickran Kazandjian, Justin Taylor, Kellye Koubek, Rabia Bukhari, Maila Wilson, Isabella Schiwy, Yahirini Rodriguez-Martinez, Justin Llano, Stephanie Fernandes, Michelle Armogan, Maurizio Affer, Sana Chaudhry, Tulasigeri M Totiger, Catalina Amador, Melinda Boone, Jennifer R. Chapman-Fredricks, Mike Georgiou, Russ Kuker, Katie Thoren, Yi Zhou, Benjamin Diamond, James E. Hoffman, Ola Landgren
Journal: Blood
Blood (2023) 142 (Supplement 1): 6740.
https://doi.org/10.1182/blood-2023-180939
Published: 2023
Journal Articles

Next Generation Sequencing Identifies Light-Chain Amyloid (AL)-Related Igvl Genes in Patients with λ Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)

Ping Zhou, Mahesh M Mansukhani, Denis Toskic, Stephanie Scalia, Lisa Lee, Sandy W. Wong, Sascha A. Tuchman, James E. Hoffman, Teresa Fogaren, Cindy Varga, Suzanne Lentzsch, Raymond Comenzo
Journal: Blood
Blood (2022) 140 (Supplement 1): 10048–10049.
https://doi.org/10.1182/blood-2022-157790
Published: 2022
Journal Articles

Sea-BCMA Mono- and Combination Therapy in Patients with Relapsed/Refractory Multiple Myeloma: Updated Results of a Phase 1 Study (SGNBCMA-001)

James E. Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Christopher Strouse, Christopher A. Yasenchak, Damian J. Green, Jeremy Sauer, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 10160–10162.
https://doi.org/10.1182/blood-2022-157347
Published: 2022
Journal Articles

Genomic Determinants of Resistance in Newly Diagnosed Multiple Myeloma Treated with Targeted-Immunotherapy

Francesco Maura, Eileen Boyle, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Bachisio Ziccheddu, Hussein Ghamlouch, Yubao Wang, James E. Hoffman, Dickran Kazandjian, Hani Hassoun, Emily Guzman, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A. Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E. Davies, Saad Usmani, Neha Korde, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1137–1139.
https://doi.org/10.1182/blood-2022-160308
Published: 2022
Journal Articles

Fc-Mediated Antibody Effector Function, Inflammation Resolution and Oligoclonality on TCR Rearrangements Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Treated with Immunotherapy Regimens

Eileen M Boyle, Francesco Maura, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Bachisio Ziccheddu, Yubao Wang, Emily Guzman, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, James E Hoffman, Dickran Kazandjian, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E Davies, Saad Usmani, Neha Korde, Ola Landgren, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 249–251.
https://doi.org/10.1182/blood-2022-165500
Published: 2022
Journal Articles

Updated Safety and Efficacy of REGN5458, a BCMAxCD3 Bispecific Antibody, Treatment for Relapsed/Refractory Multiple Myeloma: A Phase 1/2 First-in-Human Study

Naresh Bumma, Joshua Richter, Jason Brayer, Jeffrey A. Zonder, Madhav Dhodapkar, Mansi R. Shah, James E. Hoffman, Raya Mawad, Joseph J. Maly, Suzanne Lentzsch, Attaya Suvannasankha, Pourab Roy, Jyotirmoy Dey, Dhruti Chokshi, Anita Boyapati, Jenn Visich, Yariv Houvras, Karen Rodriguez Lorenc, Glenn S. Kroog, Sundar Jagannath
Journal: Blood
Blood (2022) 140 (Supplement 1): 10140–10141.
https://doi.org/10.1182/blood-2022-159969
Published: 2022
Journal Articles

The Clusterin/Von Willebrand Factor Ratio Is Significantly Lower in Marrow Plasma from AL λ-Type Than from λ-Isotype Monoclonal Gammopathy Patients

Stephanie Scalia, Denis Toskic, Ping Zhou, Mahesh M Mansukhani, Lisa Lee, Sandy W. Wong, Sascha A. Tuchman, James E. Hoffman, Teresa Fogaren, Cindy Varga, Suzanne Lentzsch, Raymond Comenzo
Journal: Blood
Blood (2022) 140 (Supplement 1): 10120–10121.
https://doi.org/10.1182/blood-2022-162352
Published: 2022
Journal Articles

Free Light-Chain Levels in Patients with Transthyretin Amyloid Cardiomyopathy in Attr-ACT

James E Hoffman, Marla B. Sultan, Balarama Gundapaneni, Ronald Witteles
Journal: Blood
Blood (2021) 138 (Supplement 1): 3787.
https://doi.org/10.1182/blood-2021-148691
Published: 2021
Journal Articles

The Genomic Landscape of Waldenström Macroglobulinemia Reveals Sustained Germinal Center Activity and Late-Developing Copy Number Aberrations

Kylee H Maclachlan, Tina Bagratuni, Efstathios Kastritis, Bachisio Ziccheddu, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Benjamin Diamond, Monika Chojnacka, Arjun Raj, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Andriy Derkach, Elli Papaemmanuil, Ahmet Dogan, Alexander Lesokhin, Ola Landgren, M. Lia Palomba, Francesco Maura, Meletios-Athanasios Dimopoulos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2394.
https://doi.org/10.1182/blood-2021-148095
Published: 2021
Journal Articles

Early, Deep, and Durable Responses, and Low Rates of Cytokine Release Syndrome with REGN5458, a BCMAxCD3 Bispecific Monoclonal Antibody, in a Phase 1/2 First-in-Human Study in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

Jeffrey A. Zonder, Joshua Richter, Naresh Bumma, Jason Brayer, James E Hoffman, William I. Bensinger, Ka Lung Wu, Linzhi Xu, Dhruti Chokshi, Anita Boyapati, Manish Sharma, Karen Rodriguez Lorenc, Glenn S Kroog, Madhav V Dhodapkar, Suzanne Lentzsch, Dennis Cooper, Sundar Jagannath
Journal: Blood
Blood (2021) 138 (Supplement 1): 160.
https://doi.org/10.1182/blood-2021-144921
Published: 2021
Journal Articles

SEA-BCMA, an Investigational Nonfucosylated Monoclonal Antibody: Ongoing Results of a Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma (SGNBCMA-001)

James E Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Michael H. Tomasson, Christopher A. Yasenchak, Damian J. Green, Hong Li, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2740.
https://doi.org/10.1182/blood-2021-146047
Published: 2021
Journal Articles

Safety and Efficacy of Letetresgene Autoleucel (lete-cel; GSK3377794) Alone or in Combination with Pembrolizumab in Relapsed and Refractory Multiple Myeloma

Taiga Nishihori, James E. Hoffman, Jonathan L. Kaufman, Anne Huff, Charlotte Snape, Amit Jain, Gurpreet Kapoor, Stefan Zajic, Sunil Suchindran, Michael Chisamore, Aaron P. Rapoport
Journal: Blood
Blood (2021) 138 (Supplement 1): 3865.
https://doi.org/10.1182/blood-2021-153004
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Prognostic Value of Specific High-Risk Cytogenetic Abnormalities and Ethnicity in Outcomes after Autologous Stem Cell Transplant in Multiple Myeloma

Fahmin Basher, Sandra Sanchez, James E. Hoffman, Lazaros J. Lekakis, Denise Pereira
Journal: Blood
Blood (2021) 138 (Supplement 1): 5041.
https://doi.org/10.1182/blood-2021-154303
Published: 2021
Journal Articles

Combination Venetoclax and Selinexor Effective in Relapsed/Refractory Multiple Myeloma with Translocation t(11;14)

Nina Nguyen, Sana Chaudhry, Tulasigeri M Totiger, Skye Montoya, Jumana Afaghani, Terrence Bradley, Francesco Maura, Dickran Kazandjian, Jennifer R Chapman, Ola Landgren, James E. Hoffman, Justin Taylor
Journal: Blood
Blood (2021) 138 (Supplement 1): 2270.
https://doi.org/10.1182/blood-2021-146925
Published: 2021
Journal Articles

Genomic and Immune Signatures Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone (D-KRd)

Francesco Maura, Eileen M Boyle, Benjamin Diamond, Patrick Blaney, Hussein Ghamlouch, Bachisio Ziccheddu, Yubao Wang, Kylee H Maclachlan, James E. Hoffman, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Dickran Kazandjian, Gunjan L Shah, Heather J Landau, David J. Chung, Sergio Giralt, Benedetto Bruno, Yanming Zhang, Arnaldo A Arbini, Ahmet Dogan, Alexander Lesokhin, Faith E Davies, Neha Korde, Gareth J Morgan, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 325.
https://doi.org/10.1182/blood-2021-149112
Published: 2021
Journal Articles

Clinical Outcomes in Relapsed/Refractory Multiple Myeloma Patients Receiving Sequential Elotuzumab and Daratumumab: A Single Center Experience

Fahmin Basher, MD PhD, Yonette Paul, MD MBBS, James E. Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-142923
Published: 2020