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Liam Hackett
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Journal Articles

Primary Endpoint Evaluation of a Multicenter, Phase 2 Study of Acalabrutinib, Venetoclax, Obinutuzumab (AVO) in a Population of Previously Untreated Patients with CLL Enriched for High-Risk Disease

Matthew S. Davids, Christine E. Ryan, Yue Ren, Liam Hackett, Jeremy Zhang, Svitlana Tyekucheva, Stacey M. Fernandes, Jennifer L. Crombie, Austin I. Kim, Matthew Weinstock, Josie Montegaard, Heather A. Walker, Claire Greenman, Victoria Patterson, Caron A. Jacobson, Ann S. LaCasce, Philippe Armand, David C. Fisher, Steve Lo, Adam J. Olszewski, Jon E. Arnason, Inhye E. Ahn, Jennifer R. Brown
Journal: Blood
Blood (2024) 144 (Supplement 1): 1865.
https://doi.org/10.1182/blood-2024-206556
Published: 2024
Journal Articles

Mechanistic Insights and Therapeutic Potential of a PRMT5 Inhibitor Combined with Venetoclax in B Cell Malignancies

Fen Zhu, Jing Wang, Christine E. Ryan, Liam Hackett, Jeremy Zhang, Stephen Jun Fei Chong, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2024-205802
Published: 2024
Journal Articles

Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies

Johannes Adrian Hildebrand, Sarah Haebe, Verena Passerini, Michael Heide, William Keay, Louisa Adolph, Lukas Ulrich, Natyra Tahiri, Raphael Koch, Jessica Duffy, Haley Martin, Liam Hackett, Jeremy Zhang, Christina Ludwig, Stefanie Wilhelm, Björn Häupl, Carmen Doebele, Michael von Bergwelt-Baildon, Axel Lechner, Tobias Herold, Christian Kellner, Martina Rudelius, Thomas Oellerich, Marc Schmidt-Supprian, Abner Louissaint, Matthew S Davids, Oliver Weigert
Journal: Blood
Blood (2023) 142 (Supplement 1): 4358.
https://doi.org/10.1182/blood-2023-174384
Published: 2023
Journal Articles

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia

Charles Herbaux, Christoph Kornauth, Stéphanie Poulain, Stephen J. F. Chong, Mary C. Collins, Rebecca Valentin, Liam Hackett, Olivier Tournilhac, François Lemonnier, Jehan Dupuis, Adrien Daniel, Cecile Tomowiak, Kamel Laribi, Loïc Renaud, Damien Roos-Weil, Cedric Rossi, Eric Van Den Neste, Cecile Leyronnas, Fatiha Merabet, Jean Valère Malfuson, Mourad Tiab, Loïc Ysebaert, Samuel Ng, Franck Morschhauser, Philipp B. Staber, Matthew S. Davids
Journal: Blood
Blood (2021) 137 (25): 3495–3506.
https://doi.org/10.1182/blood.2020007303
Published: 2021
Includes: Supplemental data
Journal Articles

Re-Wiring BCL-2 Family Anti-Apoptotic Protein Dependencies through Modulating Phosphorylation to Re-Sensitize Venetoclax-Resistant Lymphoid Malignancies to BCL-2 Inhibition

Stephen Jun Fei Chong, Mary C Collins, BS, Liam Hackett, BS, Matthew S. Davids, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-140455
Published: 2020
Journal Articles

Characterizing Specificities of Chronic Lymphoid Leukemia Harboring a BCL2 rearrangement

Charles Herbaux, MD MSc, Imelda Raczkiewicz, Kamel Laribi, MD, Loic Ysebaert, MD PhD, Agnes Daudignon, Sabine Tricot, Aurelie Caillault-Venet, Alain Jacques Delmer, MD PhD, Pascale Cornillet-Lefebvre, Cymbalista Florence, Virginie Eclache, Pierre Morel, MD, Gauthier Decool, Morgane Nudel, Romain Guieze, MD, Liam Hackett, BS, Stephen Jun Fei Chong, Mary C Collins, BS, Florence Nguyen-Khac, MD PhD, Fatiha Merabet, MD, Jasmine Chauzeix, Stéphanie Struski, MD, Jennifer R. Brown, MD PhD, Matthew S. Davids, MD, Stéphanie Poulain, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-139210
Published: 2020