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Megan M. Davis
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Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024
Journal Articles

BTK Inhibition Prevents the Induction of Myeloid-Derived Suppressor Cells in Malignancy and Improves CART Function

Benjamin F. Frost, Olga Shestova, Sara Sleiman, Brandon Simone, Feng Shen, Miroslaw Kozlowski, Michelle Wang, J. Joseph Melenhorst, Noelle Frey, Elizabeth O. Hexner, Megan M. Davis, Joseph A. Fraietta, Avery Gaymon, Rong Xu, Chia Sharpe, John C. Byrd, Mark O'Hara, Adam D. Cohen, Stephen J. Schuster, Donald L. Seigel, Carl H. June, David L. Porter, Saar Gill
Journal: Blood
Blood (2024) 144 (Supplement 1): 909.
https://doi.org/10.1182/blood-2024-202659
Published: 2024
Journal Articles

Interleukin-18 Secreting Autologous Anti-CD19 CAR T-Cells (huCART19-IL18) in Patients with Non-Hodgkin Lymphomas Relapsed or Refractory to Prior CAR T-Cell Therapy

Jakub Svoboda, James N. Gerson, Daniel J. Landsburg, Elise A. Chong, Stefan K. Barta, Sunita Dwivedy Nasta, Marco Ruella, Elizabeth O. Hexner, Amy Marshall, Rachel Leskowitz, Megan Four, Joanne Shea, Tina Matlawski, Amanda Cervini, Megan M. Davis, Mercy Gohil, John Scholler, Donald Hasenmayer, Juliana Rojas Amortegui, Andrea Brennan, Gabriela Plesa, Wei-Ting Hwang, David L. Porter, Joseph Fraietta, Stephen J. Schuster, Carl H. June
Journal: Blood
Blood (2022) 140 (Supplement 1): 4612–4614.
https://doi.org/10.1182/blood-2022-162393
Published: 2022
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021
Journal Articles

CAR T cell viability release testing and clinical outcomes: is there a lower limit?

Elise A. Chong, Bruce L. Levine, Stephan A. Grupp, Megan M. Davis, Don L. Siegel, Shannon L. Maude, Whitney L. Gladney, Noelle V. Frey, David L. Porter, Wei-Ting Hwang, Emeline R. Chong, Carl H. June, Stephen J. Schuster
Journal: Blood
Blood (2019) 134 (21): 1873–1875.
https://doi.org/10.1182/blood.2019002258
Published: 2019
Journal Articles

Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia

Joseph A Fraietta, PhD, Simon F Lacey, PhD BS, Elena Orlando, PhD, Julian Pruteanu, PhD, Mercy Gohil, Yan Wang, PhD, Alina Boesteanu, PhD, Roddy OConnor, PhD, David E Ambrose, BS, Wei-Ting Hwang, PhD, Nicholas Wilcox, Felipe Bedoya, PhD, Corin Dorfmeier, Fang Chen, PhD, Harit Parakandi, Minnal Gupta, Edward Pequignot, MS, F. Brad Johnson, PhD, Irina Kulikovskaya, Li Liu, Stefan M Lundh, BS, Jun Xu, PhD, Megan M Davis, PhD, Regina M Young, PhD, Bruce L Levine, PhD, Don L. Siegel, MD PhD, Alexander Huang, PhD, E. John Wherry, PhD, Jing Zhou, Patrick Paczkowski, Sean Mackay, Jennifer Brogdon, PhD, Hans Bitter, PhD, David L Porter, MD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3181.
https://doi.org/10.1182/blood.V130.Suppl_1.3181.3181
Published: 2017