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Mercy Gohil
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Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024
Journal Articles

Interleukin-18 Secreting Autologous Anti-CD19 CAR T-Cells (huCART19-IL18) in Patients with Non-Hodgkin Lymphomas Relapsed or Refractory to Prior CAR T-Cell Therapy

Jakub Svoboda, James N. Gerson, Daniel J. Landsburg, Elise A. Chong, Stefan K. Barta, Sunita Dwivedy Nasta, Marco Ruella, Elizabeth O. Hexner, Amy Marshall, Rachel Leskowitz, Megan Four, Joanne Shea, Tina Matlawski, Amanda Cervini, Megan M. Davis, Mercy Gohil, John Scholler, Donald Hasenmayer, Juliana Rojas Amortegui, Andrea Brennan, Gabriela Plesa, Wei-Ting Hwang, David L. Porter, Joseph Fraietta, Stephen J. Schuster, Carl H. June
Journal: Blood
Blood (2022) 140 (Supplement 1): 4612–4614.
https://doi.org/10.1182/blood-2022-162393
Published: 2022
Journal Articles

TET2 Regulates CD4 + T Follicular Helper Differentiation

Mercy Gohil, Martha S Jordan, PhD, Shannon A. Carty, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3578.
https://doi.org/10.1182/blood.V130.Suppl_1.3578.3578
Published: 2017
Journal Articles

Identification of Functional Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy of Chronic Lymphocytic Leukemia

Joseph A Fraietta, PhD, Simon F Lacey, PhD BS, Elena Orlando, PhD, Julian Pruteanu, PhD, Mercy Gohil, Yan Wang, PhD, Alina Boesteanu, PhD, Roddy OConnor, PhD, David E Ambrose, BS, Wei-Ting Hwang, PhD, Nicholas Wilcox, Felipe Bedoya, PhD, Corin Dorfmeier, Fang Chen, PhD, Harit Parakandi, Minnal Gupta, Edward Pequignot, MS, F. Brad Johnson, PhD, Irina Kulikovskaya, Li Liu, Stefan M Lundh, BS, Jun Xu, PhD, Megan M Davis, PhD, Regina M Young, PhD, Bruce L Levine, PhD, Don L. Siegel, MD PhD, Alexander Huang, PhD, E. John Wherry, PhD, Jing Zhou, Patrick Paczkowski, Sean Mackay, Jennifer Brogdon, PhD, Hans Bitter, PhD, David L Porter, MD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3181.
https://doi.org/10.1182/blood.V130.Suppl_1.3181.3181
Published: 2017
Journal Articles

Clinical Evidence That Deficiency of the Methylcytosine Dioxygenase TET2 Gene Promotes the Clonal Expansion and Therapeutic Efficacy of CD19-Directed T Cells

Joseph A Fraietta, PhD, Christopher L Nobles, PhD, Morgan A Sammons, PhD, Shannon A. Carty, MD, Stefan M Lundh, BS, Tyler Reich, Alexandria P Cogdill, BS, MB, Mercy Gohil, Jennifer J.D. Morrissette, PhD, Irina Kulikovskaya, Farzana Nazimuddin, MS, Minnal Gupta, Yan Wang, PhD, Xiaojun Liu, Regina M Young, PhD, David E Ambrose, Martha S Jordan, PhD, Katherine T Marcucci, PhD, Bruce L Levine, PhD, Yangbing Zhao, PhD MD, Michael Kalos, PhD, David L Porter, MD, Simon F Lacey, PhD BS, Shelley L Berger, PhD BS, Frederic D Bushman, PhD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1909.
https://doi.org/10.1182/blood.V130.Suppl_1.1909.1909
Published: 2017
Journal Articles

The Methylcytosine Dioxygenase TET2 Regulates CD8 + T Cell Memory Differentiation

Shannon A. Carty, MD, Mercy Gohil, Lauren B. Banks, MD PhD, Matthew E Johnson, PhD, Erietta Stelekati, PhD, Andrew D Wells, PhD, E. John Wherry, PhD, Gary A. Koretzky, MD PhD, Martha S Jordan, PhD
Journal: Blood
Blood (2016) 128 (22): 3692.
https://doi.org/10.1182/blood.V128.22.3692.3692
Published: 2016
Journal Articles

TET2 Regulates CD8 + T Cell Responses to Acute and Chronic Viral Infection

Shannon A. Carty, MD, Mercy Gohil, Erietta Stelekati, PhD, Lauren B. Banks, E. John Wherry, PhD, Gary A. Koretzky, MD PhD, Martha S Jordan, PhD
Journal: Blood
Blood (2015) 126 (23): 2227.
https://doi.org/10.1182/blood.V126.23.2227.2227
Published: 2015
Journal Articles

Integrated Immunological Analysis of the Bone Marrow Tumor Microenvironment in Myeloproliferative Neoplasms to Determine Potential Efficacy of Immune Checkpoint Blockade

Robert Orlowski, MD, Alexander Huang, Mercy Gohil, James Mangan, MD PhD, Marissa Vignali, PhD, Ryan O Emerson, PhD, Harlan Robins, PhD, Erik Yusko, PhD, Martha S Jordan, PhD, Martin Carroll, MD, D. Gary Gilliland, MD PhD, Elizabeth O Hexner, MD
Journal: Blood
Blood (2015) 126 (23): 2766.
https://doi.org/10.1182/blood.V126.23.2766.2766
Published: 2015
Journal Articles

The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability

Bryan L. Krock, Tzipora S. Eisinger-Mathason, Dionysios N. Giannoukos, Jessica E. Shay, Mercy Gohil, David S. Lee, Michael S. Nakazawa, Julie Sesen, Nicolas Skuli, M. Celeste Simon
Journal: Blood
Blood (2015) 125 (21): 3263–3272.
https://doi.org/10.1182/blood-2014-10-607267
Published: 2015
Includes: Supplemental data
Journal Articles

TET2 Regulates CD8 + T Cell Differentiation

Shannon A. Carty, MD, Mercy Gohil, Gary A Koretzky, MD PhD, Martha S Jordan, PhD
Journal: Blood
Blood (2014) 124 (21): 1423.
https://doi.org/10.1182/blood.V124.21.1423.1423
Published: 2014
Journal Articles

T-cell receptor signals direct the composition and function of the memory CD8 + T-cell pool

Jennifer E. Smith-Garvin, Jeremy C. Burns, Mercy Gohil, Tao Zou, Jiyeon S. Kim, Jonathan S. Maltzman, E. John Wherry, Gary A. Koretzky, Martha S. Jordan
Journal: Blood
Blood (2010) 116 (25): 5548–5559.
https://doi.org/10.1182/blood-2010-06-292748
Published: 2010
Includes: Supplemental data