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Journal Articles

Mutant p53 Drives the Development of Myelodysplastic Syndromes Via Dysregulating Pre-mRNA Splicing in Hematopoietic Stem and Progenitor Cells

Sergio Barajas, Sisi Chen, Sasidhar Vemula, Yuxia Yang, Edward Simpson, Wenjie Cai, Shiyu Xiao, Hongxia Chen, Stephanie Halene, Madina Sukhanova, Yunlong Liu, Omar Abdel-Wahab, Yan Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4582.
https://doi.org/10.1182/blood-2023-180382
Published: 2023
Journal Articles

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Blood
Blood (2023) 141 (3): 244–259.
https://doi.org/10.1182/blood.2022016580
Published: 2023
Includes: Supplemental data
Journal Articles

Chronic Inflammation Drives p53 Mutant Clonal Hematopoiesis Via Activating the NLRP1 Inflammasome

Sergio of Barajas, Sasidhar Vemula, Sisi Chen, Hongxia Chen, Wenjie Cai, Shiyu Xiao, Stephanie Halene, Omar Abdel-Wahab, Linsey Mayo, Sharon A. Savage, Yan Liu
Journal: Blood
Blood (2022) 140 (Supplement 1): 5743–5744.
https://doi.org/10.1182/blood-2022-169754
Published: 2022
Journal Articles

Unraveling a Novel Mechanism of Stat5 Regulation by FAK and Rac1 in Flt3ITD Induced Leukemogenesis

Anindya Chatterjee, MS, PhD, Joydeep Ghosh, Baskar Ramdas, Ph.D., Sasidhar Vemula, PhD, Holly Martin, Raghuveer Mali, Ph.D., Sarah C Nabinger, PhD, Charles B Goodwin, H. Scott Boswell, MD, Rebecca J. Chan, MD, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2012) 120 (21): 858.
https://doi.org/10.1182/blood.V120.21.858.858
Published: 2012
Journal Articles

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Sasidhar Vemula, Jianjian Shi, Raghuveer Singh Mali, Peilin Ma, Yan Liu, Philip Hanneman, Karl R. Koehler, Eri Hashino, Lei Wei, Reuben Kapur
Journal: Blood
Blood (2012) 120 (14): 2868–2878.
https://doi.org/10.1182/blood-2011-10-384172
Published: 2012
Includes: Supplemental data
Journal Articles

ROCK1 Functions As a Critical Regulator of Stress Erythropoiesis and Survival by Regulating p53

Sasidhar Vemula, PhD, Jianjian Shi, PhD, Raghuveer Mali, Ph.D., Peilin Ma, MD, PhD, Philip Hanneman, Lei Wei, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2011) 118 (21): 916.
https://doi.org/10.1182/blood.V118.21.916.916
Published: 2011
Journal Articles

Essential role for focal adhesion kinase in regulating stress hematopoiesis

Sasidhar Vemula, Baskar Ramdas, Philip Hanneman, Joseph Martin, Hilary E. Beggs, Reuben Kapur
Journal: Blood
Blood (2010) 116 (20): 4103–4115.
https://doi.org/10.1182/blood-2010-01-262790
Published: 2010
Includes: Supplemental data
Journal Articles

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

Sasidhar Vemula, Jianjian Shi, Philip Hanneman, Lei Wei, Reuben Kapur
Journal: Blood
Blood (2010) 115 (9): 1785–1796.
https://doi.org/10.1182/blood-2009-08-237222
Published: 2010
Journal Articles

ROCK1 Functions as a Suppressor of Inflammatory Cell Migration by Regulating PTEN Phosphorylation and Stability.

Sasidhar Vemula, Ph.D, Jianjian Shi, Ph.D., Philip Hanneman, Lei Wei, Ph.D., Reuben Kapur, PhD
Journal: Blood
Blood (2009) 114 (22): 240.
https://doi.org/10.1182/blood.V114.22.240.240
Published: 2009
Journal Articles

Role of Focal Adhesion Kinase in Myelotoxicity, Inflammatory Stress Response and Myeloid Cell Functions.

Sasidhar Vemula, Ph.D, Baskar Ramdas, Ph.D., Philip Hanneman, Hillary Beggs, Reuben Kapur, PhD
Journal: Blood
Blood (2009) 114 (22): 3615.
https://doi.org/10.1182/blood.V114.22.3615.3615
Published: 2009
Journal Articles

Genetic Disruption of the PI3K Regulatory Subunit, p85α Partially Normalizes Gain-of-Function PTPN11-Induced Hypersensitivity to GM-CSF in Hematopoietic Progenitors.

Charles B Goodwin, Zhenyun Yang, Sasidhar Vemula, Fuqin Yin, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3968.
https://doi.org/10.1182/blood.V114.22.3968.3968
Published: 2009
Journal Articles

ROCKI Regulates Critical Functions in Macrophages and Neutrophils.

Sasidhar Vemula, PhD, Premchand Gandra, BS, Jianjian Shi, MD/PhD, John T. O’Malley, MD/PhD, Ayek-Nati N. Ahyi, PhD, Gretta Stritesky, PhD, Norman Yeh, PhD, Mark Kaplan, MD/PhD, Lei Wei, MD/PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2007) 110 (11): 2406.
https://doi.org/10.1182/blood.V110.11.2406.2406
Published: 2007
Journal Articles

Focal Adhesion Kinase Regulates Critical Functions in Hematopoiesis.

Sasidhar Vemula, PhD, Benjamin P. Abratigue, BS, Premchand Gandra, BS, John T. O’Malley, MD/PhD, Ayek-Nati N. Ahyi, PhD, Gretta Stritesky, PhD, Norman Yeh, PhD, Mark Kaplan, MD/PhD, Hillary Beggs, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2007) 110 (11): 1407.
https://doi.org/10.1182/blood.V110.11.1407.1407
Published: 2007
Journal Articles

Structure Function Analysis of Hematopoietic Specific Src Family Kinases Lyn, Hck and Fgr Reveal a Critical Role for Lyn’s Unique Domain in Regulating Growth of Myeloid Cells That Is Distinct from the Role of Hck and Fgr’s Unique Domain.

Jinbiao Chen, PhD, Sasidhar Vemula, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2005) 106 (11): 68.
https://doi.org/10.1182/blood.V106.11.68.68
Published: 2005