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Journal Articles

Preclinical and Translational Biomarker Analyses to Inform Clinical Development of Mezigdomide (CC-92480) in Combination with Dexamethasone and Daratumumab in Multiple Myeloma

Tracy T. Chow, Michael Amatangelo, Peilin Ma, Chad C. Bjorklund, Krista Wollerman, Tiziana Civardi, Phillip Koo, Yue Zhu, Paulo Maciag, Jessica Katz, Aparna Raval, Albert Oriol, Robert Z. Orlowski, Darrell White, Paul G. Richardson, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3318.
https://doi.org/10.1182/blood-2023-178881
Published: 2023
Journal Articles

Iberdomide Enhances Dara Mediated Cytotoxicity through Upregulation of CDC Activity and Elevated NK Cell Mediated ADCC

Peilin Ma, Vinidhra Sridharan, Krista Wollerman, Debjani Dutta, Ram Kumar Singh, Sambuddo Mukherjee, Chad C. Bjorklund, Patrick R Hagner, Michael Amatangelo, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3289.
https://doi.org/10.1182/blood-2023-189423
Published: 2023
Journal Articles

Preclinical and Translational Data Support Development of Iberdomide in Combination with CD38- and SLAMF7-Directed Monoclonal Antibodies: Evidence for Rational Combinations

Michael Amatangelo, Chad Bjorklund, Peilin Ma, Krista Wollerman, William Pierceall, Sagar Lonial, MD FACP, Niels W.C.J. van de Donk, MD PhD, Rakesh Popat, Sundar Jagannath, MD, Jeffrey Zonder, Monique C. Minnema, Albert Oriol, Jeremy Larsen, Ashraf Z. Badros, MD, Paula Rodriguez-Otero, MD PhD, Pieter Sonneveld, MD PhD, Tuong Vi Nguyen, Kevin Hong, April Sorrell, Anjan Thakurta
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-137667
Published: 2020
Journal Articles

The Role of STAT5 in HOXA9-Associated Leukemia

Peilin Ma, MD, PhD, Yuqing Sun, MS, Jingya Wang, PhD, Weihua Song, MD, PhD, Tao Xu, PhD, Reuben Kapur, PhD, Jay L. Hess, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3919.
https://doi.org/10.1182/blood.V128.22.3919.3919
Published: 2016
Journal Articles

S6K1 Regulates Self-Renewal of Leukemia Initiating Cells and Normal Hematopoietic Stem Cells

Joydeep Ghosh, MSc, Anindya Chatterjee, MS,PhD, Baskar Ramdas, PhD, Michihiro Kobayashi, MD PhD, Peilin Ma, MD PhD, Yan Liu, PhD, David Plas, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2015) 126 (23): 442.
https://doi.org/10.1182/blood.V126.23.442.442
Published: 2015
Journal Articles

Modulation in the Expression of p70S6 Kinase Impairs the Engraftment and Self-Renewal of Hematopoietic Stem Cells

Joydeep Ghosh, MS, Baskar Ramdas, PhD, Anindya Chatterjee, MS,PhD, Peilin Ma, MD PhD, Michihiro Kobayashi, MDPhD, Raghuveer Mali, PhD, Yan Liu, PhD, David R. Plas, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2014) 124 (21): 252.
https://doi.org/10.1182/blood.V124.21.252.252
Published: 2014
Journal Articles

Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia

Holly Martin, Peilin Ma, MD, PhD, Anindya Chatterjee, MS, PhD, Baskar Ramdas, Ph.D., Emily Sims, Cornelis Vlaar, PhD, Suraganie Dharmawardhane, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2012) 120 (21): 810.
https://doi.org/10.1182/blood.V120.21.810.810
Published: 2012
Journal Articles

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Sasidhar Vemula, Jianjian Shi, Raghuveer Singh Mali, Peilin Ma, Yan Liu, Philip Hanneman, Karl R. Koehler, Eri Hashino, Lei Wei, Reuben Kapur
Journal: Blood
Blood (2012) 120 (14): 2868–2878.
https://doi.org/10.1182/blood-2011-10-384172
Published: 2012
Includes: Supplemental data
Journal Articles

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT

Raghuveer Singh Mali, Peilin Ma, Li-Fan Zeng, Holly Martin, Baskar Ramdas, Yantao He, Emily Sims, Sarah Nabinger, Joydeep Ghosh, Namit Sharma, Veerendra Munugalavadla, Anindya Chatterjee, Shuo Li, George Sandusky, Andrew W. Craig, Kevin D. Bunting, Gen-Sheng Feng, Rebecca J. Chan, Zhong-Yin Zhang, Reuben Kapur
Journal: Blood
Blood (2012) 120 (13): 2669–2678.
https://doi.org/10.1182/blood-2011-08-375873
Published: 2012
Includes: Supplemental data
Journal Articles

p85β regulatory subunit of class I A PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis

Subha Krishnan, Raghuveer Singh Mali, Baskar Ramdas, Emily Sims, Peilin Ma, Joydeep Ghosh, Veerendra Munugalavadla, Philip Hanneman, Joal D. Beane, Reuben Kapur
Journal: Blood
Blood (2012) 119 (17): 3951–3961.
https://doi.org/10.1182/blood-2011-05-355602
Published: 2012
Journal Articles

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Peilin Ma, MD, PhD, Raghuveer Mali, Ph.D., Li-Fan Zeng, PhD, Holly Martin, Baskar Ramdas, Ph.D., Yantao He, PhD, Emily Sims, Joydeep Ghosh, Ph.D, Sarah C Nabinger, Shuo Li, Veerendra Munugalavadla, PhD, Anindya Chatterjee, PhD, George Sandusky, MD, Andrew Craig, PhD, Kevin D. Bunting, PhD, Gen-Sheng Feng, Rebecca J. Chan, MD, PhD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2011) 118 (21): 868.
https://doi.org/10.1182/blood.V118.21.868.868
Published: 2011
Journal Articles

ROCK1 Functions As a Critical Regulator of Stress Erythropoiesis and Survival by Regulating p53

Sasidhar Vemula, PhD, Jianjian Shi, PhD, Raghuveer Mali, Ph.D., Peilin Ma, MD, PhD, Philip Hanneman, Lei Wei, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2011) 118 (21): 916.
https://doi.org/10.1182/blood.V118.21.916.916
Published: 2011
Journal Articles

The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor

Peilin Ma, Raghuveer Singh Mali, Veerendra Munugalavadla, Subha Krishnan, Baskar Ramdas, Emily Sims, Holly Martin, Joydeep Ghosh, Shuo Li, Rebecca J. Chan, Gerald Krystal, Andrew W. Craig, Clifford Takemoto, Reuben Kapur
Journal: Blood
Blood (2011) 118 (13): 3459–3469.
https://doi.org/10.1182/blood-2011-04-351809
Published: 2011
Journal Articles

Role of Intracellular Tyrosine Residues in Oncogenic KIT- Induced Transformamtion.

Peilin Ma, PhD, Holly Martin, Emily Sims, Ramdas Baskar, PhD, Joy Ghosh, Reuben Kapur, PhD
Journal: Blood
Blood (2009) 114 (22): 1435.
https://doi.org/10.1182/blood.V114.22.1435.1435
Published: 2009
Journal Articles

Repression of ROCKII by GATA-1 Inhibits Cell Proliferation during Erythroid Maturation.

Peilin Ma, PhD, Reuben Kapur, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3345.
https://doi.org/10.1182/blood.V110.11.3345.3345
Published: 2007