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Yantao He
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Journal Articles

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells.

Sarah C Nabinger, PhD, Xing Jun Li, MD, PhD, Baskar Ramdas, Ph.D., Yantao He, PhD, Xian Zhang, Ph.D., Briana Richine, Joshua Bowling, Seiji Fukuda, MD, PhD, Shreevrat Goenka, Ph.D., Ziyue Liu, Ph.D., Gen-Sheng Feng, PhD, Menggang Yu, Ph.D., George Sandusky, MD, H. Scott Boswell, MD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2420.
https://doi.org/10.1182/blood.V120.21.2420.2420
Published: 2012
Journal Articles

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT

Raghuveer Singh Mali, Peilin Ma, Li-Fan Zeng, Holly Martin, Baskar Ramdas, Yantao He, Emily Sims, Sarah Nabinger, Joydeep Ghosh, Namit Sharma, Veerendra Munugalavadla, Anindya Chatterjee, Shuo Li, George Sandusky, Andrew W. Craig, Kevin D. Bunting, Gen-Sheng Feng, Rebecca J. Chan, Zhong-Yin Zhang, Reuben Kapur
Journal: Blood
Blood (2012) 120 (13): 2669–2678.
https://doi.org/10.1182/blood-2011-08-375873
Published: 2012
Includes: Supplemental data
Journal Articles

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT

Roberto Negro, Stefania Gobessi, Pablo G. Longo, Yantao He, Zhong-Yin Zhang, Luca Laurenti, Dimitar G. Efremov
Journal: Blood
Blood (2012) 119 (26): 6278–6287.
https://doi.org/10.1182/blood-2012-01-403162
Published: 2012
Includes: Supplemental data
Journal Articles

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Peilin Ma, MD, PhD, Raghuveer Mali, Ph.D., Li-Fan Zeng, PhD, Holly Martin, Baskar Ramdas, Ph.D., Yantao He, PhD, Emily Sims, Joydeep Ghosh, Ph.D, Sarah C Nabinger, Shuo Li, Veerendra Munugalavadla, PhD, Anindya Chatterjee, PhD, George Sandusky, MD, Andrew Craig, PhD, Kevin D. Bunting, PhD, Gen-Sheng Feng, Rebecca J. Chan, MD, PhD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2011) 118 (21): 868.
https://doi.org/10.1182/blood.V118.21.868.868
Published: 2011
Journal Articles

Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors.

Sarah C Nabinger, Yantao He, Fuqin Yin, Xian Zhang, Linda Senbanjo, Seiji Fukuda, MD, PhD, Menggang Yu, Gen-Sheng Feng, Zhong-Yin Zhang, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 827.
https://doi.org/10.1182/blood.V114.22.827.827
Published: 2009