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Journal Articles

Mitoxantrone Hydrochloride Liposome Combined with Polatuzumab Vedotin and Dexamethasone (MPD) Is Highly Effective and Well Tolerated As Bridging Therapy before Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Diffuse Large B Cell Lymphoma

Xin-di Liu, Jia Cong, Lei Yang, Jing Yang, Liang Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6475.
https://doi.org/10.1182/blood-2024-209754
Published: 2024
Journal Articles

A Phase Ib/II Clinical Trial of Linperlisib Combined with Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-Cell Lymphoma: Analysis of the Phase Ib Part

Lei Yang, Xin Li, Jia Cong, Liang Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6413.
https://doi.org/10.1182/blood-2024-207469
Published: 2024
Journal Articles

Enhancing Macrophage Mediated Phagocytosis in AML: The Complementary Mechanisms of Venetoclax and Azacitidine Combination Therapy

Zhe WANG, Xufeng Chen, Simone Sidoli, Anna Skwarska, Yannan Jia, Lei Yang, Varun Gupta, Shikhar Sharma, Iannis Aifantis, Hussein A. Abbas, Naval Daver, Qi Zhang Tatarata, Marina Konopleva
Journal: Blood
Blood (2024) 144 (Supplement 1): 207.
https://doi.org/10.1182/blood-2024-198057
Published: 2024
Journal Articles

Clinical and Genetic Landscape of Peripheral T-Cell Lymphomas in Chinese Population: A Retrospective Study

Lingling Wang, Lei Yang, Fangshu Guan, Jing Chen, Yuexin Cheng, Yuqing Miao, Jingsong He, Zhen Cai, He Huang, Yi Zhao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6181.
https://doi.org/10.1182/blood-2024-199127
Published: 2024
Journal Articles

ΔSUV max between Baseline and Interim 18 f-FDG PET/CT Scans Could Better Assess the Early Response to Induction Therapy and Identify False-Positive Findings at Interim PET/CT in Extranodal NK/T-Cell Lymphoma

Lijie Zeng, Lei Yang, Mei Li, Liang Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3073.
https://doi.org/10.1182/blood-2024-210595
Published: 2024
Journal Articles

Updated Outcome from Biomarker MSC-C5b-9-Guided All-Trans Retinoic Acid Treatment for Resistant/Recurrent ITP: A Multicenter, Randomized, Open-Label, Phase 3 Clinical Trial

Menglin Li, HaiXia Fu, Hui Liu, Ru Feng, Yi Liu, Jingwen Wang, Lei Yang, Zhao Wang, Gaochao Zhang, Qingyuan Qu, Yuxiu Chen, Jianying Zhou, Mengyu Xiao, Lulu Wang, Mengtong Zang, Yun He, Xiaolu Zhu, Xiaosu Zhao, Xiaohui Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 712.
https://doi.org/10.1182/blood-2024-198335
Published: 2024
Journal Articles

The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia

Yunchao Chang, Fatemeh Keramatnia, Pankaj S. Ghate, Gisele Nishiguchi, Qingsong Gao, Ilaria Iacobucci, Lei Yang, Divyabharathi Chepyala, Ashutosh Mishra, Anthony A. High, Hiroaki Goto, Koshi Akahane, Junmin Peng, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (7): 629–642.
https://doi.org/10.1182/blood.2022017813
Published: 2023
Includes: Supplemental data
Journal Articles

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Yannan Jia, Lina Han, Cassandra L Ramage, Connie C. Weng, Lei Yang, Simona Colla, Helen Ma, Weiguo Zhang, Michael Andreeff, Naval Daver, Nitin Jain, Naveen Pemmaraju, Kapil N. Bhalla, Satu Mustjoki, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Qi Zhang, Marina Konopleva
Journal: Blood
Blood (2022) 140 (Supplement 1): 3347–3349.
https://doi.org/10.1182/blood-2022-164541
Published: 2022
Journal Articles

KLRG1 Depletion Is a Novel Therapeutic Strategy for Patients with Mature T and NK/T-Cell Lymphomas

Bimarzhan Assatova, Christopher Trevisani, Robert Willim, Jessica Duffy, Abner Louissaint, Jr., Won-Seog Kim, David J Feith, Thomas Loughran, Jr., Foster Powers, Elizabeth A Morgan, Lei Yang, Brandy Pinckney, Garrett Haskett, Matthew J Cotton, Andrew Crabbe, Jessica Beth Ziemba, Ian Brain, Tayla B. Heavican-Foral, Nora Scanlan, Gail Newton, Jaehyuk Choi, Jeffrey A Barnes, Patrick Connor Johnson, Eric D Jacobsen, Steven Greenberg, David M. Weinstock, Salvia Jain
Journal: Blood
Blood (2022) 140 (Supplement 1): 2253–2255.
https://doi.org/10.1182/blood-2022-162583
Published: 2022
Journal Articles

Preliminary Safety and Efficacy Results of EDI001: An Investigator Initiated Trial on CRISPR/Cas9-Modified Autologous CD34 + Hematopoietic Stem and Progenitor Cells for Patients with Transfusion Dependent β-Thalassemia

Jun Shi, Riguo Fang, Zhen Gao, Zhongyu Shi, Zhexiang Kuang, Yongjian Zhang, Lele Zhang, Huihui Yang, Yingchi Zhang, Dehui Zou, Liwei Fang, Jiali Sun, Qiang Li, Yao Zou, Hong Pan, Jingyu Zhao, Liyun Li, Xiao Yu, Jing Xu, Chun Xu, Yanjie Liu, Weiwei Wang, Jia Shi, Jie Liu, Jia Wang, Nian Shi, Lei Yang, Weiqiang Wang, Suyi Li, Moye Shi, Xiaoshuang Zhang, Pengfei Yuan, Wensheng Wei, Dong Wei, Tao Cheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10652–10653.
https://doi.org/10.1182/blood-2022-166365
Published: 2022
Journal Articles

Next-generation ALK inhibitors are highly active in ALK-positive large B-cell lymphoma

Clinical Trials & Observations
Jacob D. Soumerai, Allison Rosenthal, Shannon Harkins, Jessica Duffy, Carmen Mecca, Yingbing Wang, Ravinder K. Grewal, Areej R. El-Jawahri, Huiyun Liu, Cedric Menard, Ahmet Dogan, Lei Yang, Lisa M. Rimsza, Kurt Bantilan, Haley Martin, Matthew Lei, Sydney Mohr, Anna Kurilovich, Olga Kudryashova, Ekaterina Postovalova, Valentina Nardi, Jeremy S. Abramson, Roberto Chiarle, Andrew D. Zelenetz, Abner Louissaint, Jr.
Journal: Blood
Blood (2022) 140 (16): 1822–1826.
https://doi.org/10.1182/blood.2022015443
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1

Wenchao Wu, Geoffrey M. Nelson, Raphael Koch, Katherine A. Donovan, Radosław P. Nowak, Tayla B. Heavican-Foral, Ajit J. Nirmal, Huiyun Liu, Lei Yang, Jessica Duffy, Foster Powers, Kristen E. Stevenson, Marcus Kenneth Jones, Samuel Y. Ng, Gongwei Wu, Salvia Jain, Ran Xu, Sam Amaka, Christopher Trevisani, Nicholas L. Donaldson, Patrick R. Hagner, Laurence de Leval, Philippe Gaulard, Javeed Iqbal, Anjan Thakurta, Eric S. Fischer, Karen Adelman, David M. Weinstock
Journal: Blood
Blood (2022) 139 (13): 2024–2037.
https://doi.org/10.1182/blood.2021014701
Published: 2022
Includes: Supplemental data
Journal Articles

Primary cytotoxic T-cell lymphomas harbor recurrent targetable alterations in the JAK-STAT pathway

Katie Lee, Mark G. Evans, Lei Yang, Spencer Ng, Caroline Snowden, Michael Khodadoust, Ryanne A. Brown, Nicholas A. Trum, Christiane Querfeld, Linda T. Doan, Jinming Song, Hailing Zhang, Alejandro A. Gru, Gary S. Wood, David A. Wada, Vignesh Shanmugam, Paul L. Haun, Jon C. Aster, Lyn M. Duncan, Joan Guitart, David M. Weinstock, Valentina Nardi, Jaehyuk Choi
Journal: Blood
Blood (2021) 138 (23): 2435–2440.
https://doi.org/10.1182/blood.2021012536
Published: 2021
Includes: Supplemental data
Journal Articles

Degradation of Janus kinases in CRLF2 -rearranged acute lymphoblastic leukemia

Yunchao Chang, Jaeki Min, Jamie A. Jarusiewicz, Marisa Actis, Shanshan Yu-Chen Bradford, Anand Mayasundari, Lei Yang, Divyabharathi Chepyala, Lisa J. Alcock, Kathryn G. Roberts, Stanley Nithianantham, Dylan Maxwell, Lauren Rowland, Randolph Larsen, Aman Seth, Hiroaki Goto, Toshihiko Imamura, Koshi Akahane, Baranda S. Hansen, Shondra M. Pruett-Miller, Elisabeth M. Paietta, Mark R. Litzow, Chunxu Qu, Jun J. Yang, Marcus Fischer, Zoran Rankovic, Charles G. Mullighan
Journal: Blood
Blood (2021) 138 (23): 2313–2326.
https://doi.org/10.1182/blood.2020006846
Published: 2021
Includes: Supplemental data
Journal Articles

Development of Proteolytic Targeting Chimeras to Target Lck in T-Cell Acute Lymphoblastic Leukemia

Jianzhong Hu, Jamie Jarusiewicz, Jaeki Min, Lei Yang, Divyabharathi Chepyala, Marisa Actis, Lauren Rowland, Guoqing Du, Brandon Smart, Dylan Maxwell, Boer Xie, Satoshi Yoshimura, Junmin Peng, David Teachey, Zoran Rankovic, Jun J. Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 867.
https://doi.org/10.1182/blood-2021-147024
Published: 2021
Journal Articles

Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis

Sachiko Kanaji, MD PhD, Taisuke Kanaji, MD PhD, My-Nuong Vo, PhD, Alessandro Zarpellon, PhD, Ryan Shapiro, Rajesh Belani, MD, Minh-Ha Do, PhD, Xiang-Lei Yang, PhD, Zaverio M. Ruggeri, MD, Paul Schimmel, PhD
Journal: Blood
Blood (2016) 128 (22): 1476.
https://doi.org/10.1182/blood.V128.22.1476.1476
Published: 2016
Journal Articles

CD163+ Tumor Associated Macrophages Predict Inferior Outcome in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP

Hong Zeng, Yongqiang Wei, Muchen Xie, Lei Yang, Fen Huang, Xiaolei Wei, Dr., Xiaoxiao Hao, Qi Wei, Ru Feng
Journal: Blood
Blood (2015) 126 (23): 5023.
https://doi.org/10.1182/blood.V126.23.5023.5023
Published: 2015
Journal Articles

The Prognostic Significance of Tumor-Associated Macrophages and NK Cells in Patients with Diffuse Large B-Cell Lymphoma Treated with RCHOP

Muchen Xie, MD, Yongqiang Wei, MD, Lei Yang, MD, Fen Huang, MD, Xiaolei Wei, PhD, Hui Jing, MD, Xiaoxiao Hao, Hong Zeng, PhD, Ru Feng, Pro
Journal: Blood
Blood (2014) 124 (21): 5390.
https://doi.org/10.1182/blood.V124.21.5390.5390
Published: 2014
Journal Articles

Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia

Li Guo, Lei Yang, Edwin R. Speck, Rukhsana Aslam, Michael Kim, Christopher G. J. McKenzie, Alan H. Lazarus, Heyu Ni, Ming Hou, John Freedman, John W. Semple
Journal: Blood
Blood (2014) 123 (3): 422–427.
https://doi.org/10.1182/blood-2013-08-523308
Published: 2014
Includes: Supplemental data
Journal Articles

Novel Protein Agonist of Thrombopoiesis Acts Via a Physiocrine Pathway Distinct From That of Thrombopoietin

Minh-Ha T Do, PhD, Wei Zhang, PhD, Kyle Chiang, PhD, Chi-Fang Wu, PhD, Chulho Park, PhD, Quansheng Zhou, MD/PhD, My-Nuong Vo, PhD, Xiang-Lei Yang, PhD, Lori Kunkel, MD, Melissa A Ashlock, MD, John D Mendlein, PhD, Rajesh Belani, MD, Alain P Vasserot, PhD, Jeffry D Watkins, PhD
Journal: Blood
Blood (2011) 118 (21): 2376.
https://doi.org/10.1182/blood.V118.21.2376.2376
Published: 2011