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Journal Articles

The Causality between Immune Thrombocytopenia and Thrombosis : A Bidirectional Two-Sample Mendelian Randomization Study

Yajing Zhao, Shouqing Han, Xinguang Liu, Li Guo
Journal: Blood
Blood (2024) 144 (Supplement 1): 5429.
https://doi.org/10.1182/blood-2024-206920
Published: 2024
Journal Articles

The Actin Bundling Protein L-Plastin Mediates Platelet Force Generation and Thrombosis

Seema Bhatlekar, Shancy Jacob, Marina Tistao, Molly Y Mollica, Nicole Rhoads, Lili Chen, Bhanu Kanth Manne, Darian Murray, Siqi Guo, Sharon Celeste Morley, Jesse W Rowley, Matthew T. Rondina, Raymond Adili, Jose A. Lopez, Li Guo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2560.
https://doi.org/10.1182/blood-2023-178052
Published: 2023
Journal Articles

Mitochondrial Fission Protein Drp1 Regulates Platelet Function

Shancy Jacob, Marina Tistao, Abigail Ajanel Gomez, Frederik Denorme, Yasuhiro Kosaka, Bhanu Kanth Manne, Li Guo, Robert A. Campbell, Matthew T. Rondina, Jesse W Rowley
Journal: Blood
Blood (2023) 142 (Supplement 1): 1201.
https://doi.org/10.1182/blood-2023-187556
Published: 2023
Journal Articles

Anti-PD-1 Antibody (Tislelizumab) Combined with R-CHOP for the Treatment of Previously Untreated Primary Mediastinal B-Cell Lymphoma: A Prospective Phase II Study

Mei Wu, Lin Zhu, Shan Li, Tuerde Jiaerbao, Shanshan Wang, Xiao Liang, Xin Hu, Li Guo, Abulikemujiang Adili, Xianmusiya Maimaitirexiati, Ruirui Ren, Zhihua Yao, Shuna Yao, Shujuan Wen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6236.
https://doi.org/10.1182/blood-2023-182504
Published: 2023
Journal Articles

MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis

Bhanu Kanth Manne, Robert A. Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Irina Portier, Elizabeth A. Middleton, Neal D. Tolley, Yasuhiro Kosaka, Emilie Montenont, Li Guo, Jesse W. Rowley, Paul F. Bray, Shancy Jacob, Rikiro Fukanaga, Christopher Proud, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2022) 140 (23): 2477–2489.
https://doi.org/10.1182/blood.2022015568
Published: 2022
Includes: Supplemental data
Journal Articles

Actin Bundling Protein L-Plastin Regulates Megakaryocyte Membrane Rigidity and Platelet Spreading

Li Guo, Seema Bhatlekar, Shancy P Jacob, Bhanu Kanth Manne, Elizabeth Kolawole, Emilia A Tugolukova, Siqi Guo, Yasuhiro Kosaka, Cindy Barba, Brian Evavold, Sharon Celesty Morley, Robert A. Campbell, Paul F. Bray
Journal: Blood
Blood (2022) 140 (Supplement 1): 5510–5511.
https://doi.org/10.1182/blood-2022-169517
Published: 2022
Journal Articles

Mitofusin2 (MFN2) Preserves Mitochondrial Integrity and Function in Megakaryocytes and Platelets

Shancy P Jacob, Yasuhiro Kosaka, Seema Bhatlekar, Alexandra Moody, Victoria Moody, Emilia A Tugolukova, Grayson A Hull, Frederik Denorme, Bhanu Kanth Manne, Li Guo, Rhonda Souvenir, Alicia Eustes, Kelly B Hoerger, Neal D Tolley, Robert A. Campbell, Matthew T. Rondina, E. Dale Abel, Paul F. Bray, Andrew S. Weyrich, Jesse W Rowley
Journal: Blood
Blood (2021) 138 (Supplement 1): 3137.
https://doi.org/10.1182/blood-2021-154329
Published: 2021
Journal Articles

Increased Platelet S100A8/S100A9 Associated with Vasculitis in Granulomatosis with Polyangiitis (GPA)

Li Guo, Ben Berger, Jesse W Rowley, Neal D Tolley, Bhanu Kanth Manne, Juan Su, Sikui Shen, Paul D. Crane, Kimberly A Queisser, Aaron C Petrey, Curry L. Koening, Matthew T. Rondina
Journal: Blood
Blood (2021) 138 (Supplement 1): 3142.
https://doi.org/10.1182/blood-2021-152291
Published: 2021
Journal Articles

Platelet MHC class I mediates CD8 + T-cell suppression during sepsis

Li Guo, Sikui Shen, Jesse W. Rowley, Neal D. Tolley, Wenwen Jia, Bhanu Kanth Manne, Kyra N. McComas, Ben Bolingbroke, Yasuhiro Kosaka, Krystin Krauel, Frederik Denorme, Shancy P. Jacob, Alicia S. Eustes, Robert A. Campbell, Elizabeth A. Middleton, Xiao He, Samuel M. Brown, Craig N. Morrell, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2021) 138 (5): 401–416.
https://doi.org/10.1182/blood.2020008958
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Platelet gene expression and function in patients with COVID-19

Bhanu Kanth Manne, Frederik Denorme, Elizabeth A. Middleton, Irina Portier, Jesse W. Rowley, Chris Stubben, Aaron C. Petrey, Neal D. Tolley, Li Guo, Mark Cody, Andrew S. Weyrich, Christian C. Yost, Matthew T. Rondina, Robert A. Campbell
Journal: Blood
Blood (2020) 136 (11): 1317–1329.
https://doi.org/10.1182/blood.2020007214
Published: 2020
Includes: Supplemental data
Journal Articles

Sepsis alters the transcriptional and translational landscape of human and murine platelets

Elizabeth A. Middleton, Jesse W. Rowley, Robert A. Campbell, Colin K. Grissom, Samuel M. Brown, Sarah J. Beesley, Hansjörg Schwertz, Yasuhiro Kosaka, Bhanu K. Manne, Krystin Krauel, Neal D. Tolley, Alicia S. Eustes, Li Guo, Robert Paine, III, Estelle S. Harris, Guy A. Zimmerman, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2019) 134 (12): 911–923.
https://doi.org/10.1182/blood.2019000067
Published: 2019
Includes: Supplemental data
Journal Articles

Neutrophil Extracellular Traps Exacerbate Inflammatory Responses and Thrombotic Tendency in Both a Murine Colitis Model and Patients with Inflammatory Bowel Disease

Muhua Cao, MD, Muxin Yu, PhD, Yan Zhang, MD, Dongxia Tong, MD, Li Guo, MDPhD, Chunxu Wang, MD, Tao Li, MD, Xiaoyan Yang, MD, Cong Zhang, MD, Junjie Kou, MD PhD, Yayan Bi, MD PhD, Jin Zhou, Jialan Shi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 994.
https://doi.org/10.1182/blood.V130.Suppl_1.994.994
Published: 2017
Journal Articles

Increased MHC Class I Expression on Platelets in Human and Murine Sepsis

Li Guo, MDPhD, Sikui Shen, MD, Jesse W Rowley, PhD, Kyra Mccomas, Juan Su, MD, Bhanu Kanth Manne, PhD, Ben Berger, Elizabeth Middleton, MD, Robert A. Campbell, PhD, Andrew S. Weyrich, PhD, Matthew T. Rondina, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1036.
https://doi.org/10.1182/blood.V130.Suppl_1.1036.1036
Published: 2017
Journal Articles

CD20 + B-cell depletion therapy suppresses murine CD8 + T-cell–mediated immune thrombocytopenia

Brief Report
Li Guo, Rick Kapur, Rukshana Aslam, Edwin R. Speck, Anne Zufferey, Yajing Zhao, Michael Kim, Alan H. Lazarus, Heyu Ni, John W. Semple
Journal: Blood
Blood (2016) 127 (6): 735–738.
https://doi.org/10.1182/blood-2015-06-655126
Published: 2016
Includes: Supplemental data
Journal Articles

Thymic-Derived Tolerizing Dendritic Cells Are up-Regulated upon Treatment with Intravenous Immunoglobulin or Splenectomy in a Murine Model of Immune Thrombocytopenia

Rick Kapur, MD PhD, Rukhsana Aslam, PhD, Edwin R. Speck, BRT, Michael Kim, BSc, Anne Zufferey, PhD, Li Guo, MD, George B. Segel, MD, Heyu Ni, MD PhD, John W. Semple, PhD
Journal: Blood
Blood (2015) 126 (23): 2251.
https://doi.org/10.1182/blood.V126.23.2251.2251
Published: 2015
Journal Articles

Murine Bone Marrow-Derived Megakaryocytes Are Capable of Antigen Cross-Presentation on Major Histocompatibility Class (MHC) I Molecules

Anne Zufferey, PhD, Edwin R. Speck, BRT, Li Guo, MD, Rukhsana Aslam, PhD, Rick Kapur, MD PhD, John W. Semple, PhD
Journal: Blood
Blood (2015) 126 (23): 3465.
https://doi.org/10.1182/blood.V126.23.3465.3465
Published: 2015
Journal Articles

C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD
Journal: Blood
Blood (2015) 126 (23): 3561.
https://doi.org/10.1182/blood.V126.23.3561.3561
Published: 2015
Journal Articles

CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD
Journal: Blood
Blood (2015) 126 (23): 2342.
https://doi.org/10.1182/blood.V126.23.2342.2342
Published: 2015
Journal Articles

CD20 B Cell Depleting Therapy Is Associated with up-Regulation of CD8 + CD25 high Foxp3 + T Regulatory Cells in a Murine Model of Immune Thrombocytopenia (ITP)

Li Guo, MD, Rukhsana Aslam, PhD, Yajing Zhao, Edwin R. Speck, BRT, Heyu Ni, MD PhD, John W. Semple, PhD
Journal: Blood
Blood (2014) 124 (21): 2785.
https://doi.org/10.1182/blood.V124.21.2785.2785
Published: 2014
Journal Articles

Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia

Li Guo, Lei Yang, Edwin R. Speck, Rukhsana Aslam, Michael Kim, Christopher G. J. McKenzie, Alan H. Lazarus, Heyu Ni, Ming Hou, John Freedman, John W. Semple
Journal: Blood
Blood (2014) 123 (3): 422–427.
https://doi.org/10.1182/blood-2013-08-523308
Published: 2014
Includes: Supplemental data