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Bhanu Kanth Manne
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Journal Articles

The Actin Bundling Protein L-Plastin Mediates Platelet Force Generation and Thrombosis

Free
Seema Bhatlekar, Shancy Jacob, Marina Tistao, Molly Y Mollica, Nicole Rhoads, Lili Chen, Bhanu Kanth Manne, Darian Murray, Siqi Guo, Sharon Celeste Morley, Jesse W Rowley, Matthew T. Rondina, Raymond Adili, Jose A. Lopez, Li Guo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2560.
https://doi.org/10.1182/blood-2023-178052
Published: 2023
Journal Articles

Mitochondrial Fission Protein Drp1 Regulates Platelet Function

Free
Shancy Jacob, Marina Tistao, Abigail Ajanel Gomez, Frederik Denorme, Yasuhiro Kosaka, Bhanu Kanth Manne, Li Guo, Robert A. Campbell, Matthew T. Rondina, Jesse W Rowley
Journal: Blood
Blood (2023) 142 (Supplement 1): 1201.
https://doi.org/10.1182/blood-2023-187556
Published: 2023
Journal Articles

MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis

Free
Bhanu Kanth Manne, Robert A. Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Irina Portier, Elizabeth A. Middleton, Neal D. Tolley, Yasuhiro Kosaka, Emilie Montenont, Li Guo, Jesse W. Rowley, Paul F. Bray, Shancy Jacob, Rikiro Fukanaga, Christopher Proud, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2022) 140 (23): 2477–2489.
https://doi.org/10.1182/blood.2022015568
Published: 2022
Includes: Supplemental data
Journal Articles

Actin Bundling Protein L-Plastin Regulates Megakaryocyte Membrane Rigidity and Platelet Spreading

Free
Li Guo, Seema Bhatlekar, Shancy P Jacob, Bhanu Kanth Manne, Elizabeth Kolawole, Emilia A Tugolukova, Siqi Guo, Yasuhiro Kosaka, Cindy Barba, Brian Evavold, Sharon Celesty Morley, Robert A. Campbell, Paul F. Bray
Journal: Blood
Blood (2022) 140 (Supplement 1): 5510–5511.
https://doi.org/10.1182/blood-2022-169517
Published: 2022
Journal Articles

Mitofusin2 (MFN2) Preserves Mitochondrial Integrity and Function in Megakaryocytes and Platelets

Free
Shancy P Jacob, Yasuhiro Kosaka, Seema Bhatlekar, Alexandra Moody, Victoria Moody, Emilia A Tugolukova, Grayson A Hull, Frederik Denorme, Bhanu Kanth Manne, Li Guo, Rhonda Souvenir, Alicia Eustes, Kelly B Hoerger, Neal D Tolley, Robert A. Campbell, Matthew T. Rondina, E. Dale Abel, Paul F. Bray, Andrew S. Weyrich, Jesse W Rowley
Journal: Blood
Blood (2021) 138 (Supplement 1): 3137.
https://doi.org/10.1182/blood-2021-154329
Published: 2021
Journal Articles

Increased Platelet S100A8/S100A9 Associated with Vasculitis in Granulomatosis with Polyangiitis (GPA)

Free
Li Guo, Ben Berger, Jesse W Rowley, Neal D Tolley, Bhanu Kanth Manne, Juan Su, Sikui Shen, Paul D. Crane, Kimberly A Queisser, Aaron C Petrey, Curry L. Koening, Matthew T. Rondina
Journal: Blood
Blood (2021) 138 (Supplement 1): 3142.
https://doi.org/10.1182/blood-2021-152291
Published: 2021
Journal Articles

Platelet MHC class I mediates CD8 + T-cell suppression during sepsis

Free
Li Guo, Sikui Shen, Jesse W. Rowley, Neal D. Tolley, Wenwen Jia, Bhanu Kanth Manne, Kyra N. McComas, Ben Bolingbroke, Yasuhiro Kosaka, Krystin Krauel, Frederik Denorme, Shancy P. Jacob, Alicia S. Eustes, Robert A. Campbell, Elizabeth A. Middleton, Xiao He, Samuel M. Brown, Craig N. Morrell, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2021) 138 (5): 401–416.
https://doi.org/10.1182/blood.2020008958
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Blockade of Human PAR4 in Novel Humanized Mouse Strains Supports PAR4 As a Potential Target in Stroke: Ex Vivo Demonstration of Platelet Hyperreactivity of the Thr120 Variant

Free
Robert A. Campbell, PhD, Michelle L. Stoller, PhD, Frederik Denorme, PhD, Bhanu Kanth Manne, PhD, Seema Bhatlekar, PhD, Emilia A Tugolukova, B.S., Paul F. Bray, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-136178
Published: 2020
Journal Articles

Platelet gene expression and function in patients with COVID-19

Free
Bhanu Kanth Manne, Frederik Denorme, Elizabeth A. Middleton, Irina Portier, Jesse W. Rowley, Chris Stubben, Aaron C. Petrey, Neal D. Tolley, Li Guo, Mark Cody, Andrew S. Weyrich, Christian C. Yost, Matthew T. Rondina, Robert A. Campbell
Journal: Blood
Blood (2020) 136 (11): 1317–1329.
https://doi.org/10.1182/blood.2020007214
Published: 2020
Includes: Supplemental data
Journal Articles

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

Free
Elizabeth A. Middleton, Xue-Yan He, Frederik Denorme, Robert A. Campbell, David Ng, Steven P. Salvatore, Maria Mostyka, Amelia Baxter-Stoltzfus, Alain C. Borczuk, Massimo Loda, Mark J. Cody, Bhanu Kanth Manne, Irina Portier, Estelle S. Harris, Aaron C. Petrey, Ellen J. Beswick, Aleah F. Caulin, Anthony Iovino, Lisa M. Abegglen, Andrew S. Weyrich, Matthew T. Rondina, Mikala Egeblad, Joshua D. Schiffman, Christian Con Yost
Journal: Blood
Blood (2020) 136 (10): 1169–1179.
https://doi.org/10.1182/blood.2020007008
Published: 2020
Includes: Supplemental data
Journal Articles

Platelet necrosis mediates ischemic stroke outcome in mice

Free
Frederik Denorme, Bhanu Kanth Manne, Irina Portier, Alicia S. Eustes, Yasuhiro Kosaka, Benjamin T. Kile, Matthew T. Rondina, Robert A. Campbell
Journal: Blood
Blood (2020) 135 (6): 429–440.
https://doi.org/10.1182/blood.2019002124
Published: 2020
Includes: Supplemental data
Journal Articles

Cyclophilin D Mediated Platelet Necrosis Regulates Ischemic Stroke Outcomes in Mice

Free
Frederik Denorme, PhD, Bhanu Kanth Manne, PhD, Yasuhiro Kosaka, PhD, Benjamin Kile, PhD, Matthew T. Rondina, MD, Robert A. Campbell, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3620.
https://doi.org/10.1182/blood-2019-123839
Published: 2019
Journal Articles

Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3

Free
Robert A. Campbell, Hansjorg Schwertz, Eugenio D. Hottz, Jesse W. Rowley, Bhanu Kanth Manne, A. Valance Washington, Robert Hunter-Mellado, Neal D. Tolley, Miles Christensen, Alicia S. Eustes, Emilie Montenont, Seema Bhatlekar, Cassandra H. Ventrone, Beth D. Kirkpatrick, Kristen K. Pierce, Stephen S. Whitehead, Sean A. Diehl, Paul F. Bray, Guy A. Zimmerman, Yasuhiro Kosaka, Patricia T. Bozza, Fernando A. Bozza, Andrew S. Weyrich, Matthew T. Rondina
Journal: Blood
Blood (2019) 133 (19): 2013–2026.
https://doi.org/10.1182/blood-2018-09-873984
Published: 2019
Includes: Supplemental data
Journal Articles

Increased MHC Class I Expression on Platelets in Human and Murine Sepsis

Free
Li Guo, MDPhD, Sikui Shen, MD, Jesse W Rowley, PhD, Kyra Mccomas, Juan Su, MD, Bhanu Kanth Manne, PhD, Ben Berger, Elizabeth Middleton, MD, Robert A. Campbell, PhD, Andrew S. Weyrich, PhD, Matthew T. Rondina, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1036.
https://doi.org/10.1182/blood.V130.Suppl_1.1036.1036
Published: 2017
Journal Articles

Inhibition of MAP Kinase-Interacting Kinase-1 (Mnk1) Regulates Platelet Functional Responses and Protein Synthesis in Megakaryocytes

Free
Bhanu Kanth Manne, PhD, Rachit Badolia, PhD, Robert A. Campbell, PhD, Satya P. Kunapuli, PhD, Andrew S. Weyrich, PhD, Matthew T. Rondina, MD
Journal: Blood
Blood (2016) 128 (22): 711.
https://doi.org/10.1182/blood.V128.22.711.711
Published: 2016
Journal Articles

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets

Free
Jesse W. Rowley, Stéphane Chappaz, Aurélie Corduan, Mark M. W. Chong, Robert Campbell, Amanda Khoury, Bhanu Kanth Manne, Jeremy G. T. Wurtzel, James V. Michael, Lawrence E. Goldfinger, Michele M. Mumaw, Marvin T. Nieman, Benjamin T. Kile, Patrick Provost, Andrew S. Weyrich
Journal: Blood
Blood (2016) 127 (14): 1743–1751.
https://doi.org/10.1182/blood-2015-07-661371
Published: 2016
Includes: Supplemental data
Journal Articles

G q -mediated Akt translocation to the membrane: a novel PIP 3 -independent mechanism in platelets

Free
Rachit Badolia, Bhanu Kanth Manne, Carol Dangelmaier, Jonathan Chernoff, Satya P. Kunapuli
Journal: Blood
Blood (2015) 125 (1): 175–184.
https://doi.org/10.1182/blood-2014-05-576306
Published: 2015
Includes: Supplemental data