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Journal Articles

Racial Disparities in in-Hospital Outcomes of Venous Thromboembolic Events in Patients with Diffuse Large B-Cell Lymphoma

Dosbai Saparov, Henry Becerra, Mustafa Wasifuddin, Ifeanyi Nnamdi Uche, Shakirat Gold-Olufadi, Azamat Abdyraimov, Narek Hakobyan, Hesham Ali Abowali, Akriti Pokhrel, Ruchi Yadav, Rukhsana Aslam, Neharika Shrestha, Aleksandr Markov, Jen Chin Wang

Blood (2024) 144 (Supplement 1): 7825.

https://doi.org/10.1182/blood-2024-211776

Published: 2024

Journal Articles

CD8+ T Cells from Patients with CLL Show Evidence of Granzyme B and Perforin Cytotoxic Capacity, Which Is Enhanced upon Exposure to Exogenous IL2 and/or IL21

Cristina Paraschivescu, Shivani Chhabra, Rukhsana Aslam, Byeongho Jung, Gerardo Ferrer, Jacqueline C. Barrientos, Joanna M. Rhodes, Jonathan E. Kolitz, Steven L Allen, Kanti R Rai, Barbara Sherry, Nicholas Chiorazzi

Blood (2022) 140 (Supplement 1): 7000–7001.

https://doi.org/10.1182/blood-2022-170023

Published: 2022

Journal Articles

Activated CLL B Cells Variably Modulate microRNA-155 Levels in Naïve CD4 + T Cells, and the Direction and Magnitude of microRNA-155 Change Correlates with Th17 Levels and Clinical Course

Byeongho Jung, BS, Gerardo Ferrer, PhD, Pui Yan Chiu, Rukhsana Aslam, MD, Florencia Palacios, PhD, Barbara Sherry, PhD, Nicholas Chiorazzi, MD

Blood (2018) 132 (Supplement 1): 4402.

https://doi.org/10.1182/blood-2018-99-116505

Published: 2018

Journal Articles

Extended Survival in CLL Patients Who Discontinued Idelalisib Because of Colitis Correlates with Higher Th17 Levels in Blood and Colon Tissue

Rukhsana Aslam, MD, Jacqueline C Barrientos, MD MS, Gerardo Ferrer, PhD, Pui Yan Chiu, Kanti R Rai, MD, Nicholas Chiorazzi, MD, Barbara Sherry, PhD

Blood (2018) 132 (Supplement 1): 1848.

https://doi.org/10.1182/blood-2018-99-116910

Published: 2018

Journal Articles

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10

Rick Kapur, Michael Kim, Rukhsana Aslam, Mark J. McVey, Arata Tabuchi, Alice Luo, Jonathan Liu, Yuan Li, Shanjeevan Shanmugabhavananthan, Edwin R. Speck, Anne Zufferey, George Yousef, Haibo Zhang, Matthew T. Rondina, Andrew S. Weyrich, Leendert Porcelijn, Wolfgang M. Kuebler, Arthur S. Slutsky, John W. Semple

Blood (2017) 129 (18): 2557–2569.

https://doi.org/10.1182/blood-2016-12-758185

Published: 2017

Includes: Supplemental data

Journal Articles

Successful Treatment of Thrombocytopenia with Staphylococcal Protein A (PRTX-100) in a Murine Model of Immune Thrombocytopenia (ITP)

John W. Semple, PhD, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Michael Kim, BSc, Anne Zufferey, PhD, Heyu Ni, MD PhD, Michelle Catalina, PhD, Richard Francovitch, PhD

Blood (2015) 126 (23): 1045.

https://doi.org/10.1182/blood.V126.23.1045.1045

Published: 2015

Journal Articles

Thymic-Derived Tolerizing Dendritic Cells Are up-Regulated upon Treatment with Intravenous Immunoglobulin or Splenectomy in a Murine Model of Immune Thrombocytopenia

Rick Kapur, MD PhD, Rukhsana Aslam, PhD, Edwin R. Speck, BRT, Michael Kim, BSc, Anne Zufferey, PhD, Li Guo, MD, George B. Segel, MD, Heyu Ni, MD PhD, John W. Semple, PhD

Blood (2015) 126 (23): 2251.

https://doi.org/10.1182/blood.V126.23.2251.2251

Published: 2015

Journal Articles

Murine Bone Marrow-Derived Megakaryocytes Are Capable of Antigen Cross-Presentation on Major Histocompatibility Class (MHC) I Molecules

Anne Zufferey, PhD, Edwin R. Speck, BRT, Li Guo, MD, Rukhsana Aslam, PhD, Rick Kapur, MD PhD, John W. Semple, PhD

Blood (2015) 126 (23): 3465.

https://doi.org/10.1182/blood.V126.23.3465.3465

Published: 2015

Journal Articles

C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD

Blood (2015) 126 (23): 3561.

https://doi.org/10.1182/blood.V126.23.3561.3561

Published: 2015

Journal Articles

CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD

Blood (2015) 126 (23): 2342.

https://doi.org/10.1182/blood.V126.23.2342.2342

Published: 2015

Journal Articles

CD20 B Cell Depleting Therapy Is Associated with up-Regulation of CD8 + CD25 high Foxp3 + T Regulatory Cells in a Murine Model of Immune Thrombocytopenia (ITP)

Li Guo, MD, Rukhsana Aslam, PhD, Yajing Zhao, Edwin R. Speck, BRT, Heyu Ni, MD PhD, John W. Semple, PhD

Blood (2014) 124 (21): 2785.

https://doi.org/10.1182/blood.V124.21.2785.2785

Published: 2014

Journal Articles

Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia

Li Guo, Lei Yang, Edwin R. Speck, Rukhsana Aslam, Michael Kim, Christopher G. J. McKenzie, Alan H. Lazarus, Heyu Ni, Ming Hou, John Freedman, John W. Semple

Blood (2014) 123 (3): 422–427.

https://doi.org/10.1182/blood-2013-08-523308

Published: 2014

Includes: Supplemental data

Journal Articles

Megakaryocyte Abnormalities Occur In The Absence Of Cell-Mediated Immunity In a Murine Model Of Passive Immune Thrombocytopenia (ITP)

John W. Semple, PhD, Kristin Hunt, Yu Hou, Rukhsana Aslam, PhD, Edwin R. Speck, Heyu Ni, MD, PhD, Alan H Lazarus, PhD

Blood (2013) 122 (21): 3537.

https://doi.org/10.1182/blood.V122.21.3537.3537

Published: 2013

Journal Articles

Human and Murine Immune Thrombocytopenia (ITP) Is Associated with a Peripheral Deficiency of CD4- T Regulatory Cells (Tc-regs)

John W. Semple, PhD, Daoxin Ma, PhD, Rukhsana Aslam, PhD, Ming Hou, Heyu Ni, MD, PhD, Yu Hu

Blood (2012) 120 (21): 3333.

https://doi.org/10.1182/blood.V120.21.3333.3333

Published: 2012

Journal Articles

Thrombopoietin Can Induce Tolerogenic Responses Via the Modulation of Thymic and Splenic T Lymphocyte Populations in a Murine Model of Immune Thrombocytopenia (ITP)

John W. Semple, PhD, Xu Zhang, Yu Hu, Li Guo, Edwin R. Speck, Heyu Ni, MD, PhD, Rukhsana Aslam, PhD

Blood (2012) 120 (21): 1088.

https://doi.org/10.1182/blood.V120.21.1088.1088

Published: 2012

Journal Articles

Thymic retention of CD4 + CD25 + FoxP3 + T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia

Rukhsana Aslam, Yu Hu, Simon Gebremeskel, George B. Segel, Edwin R. Speck, Li Guo, Michael Kim, Heyu Ni, John Freedman, John W. Semple

Blood (2012) 120 (10): 2127–2132.

https://doi.org/10.1182/blood-2012-02-413526

Published: 2012

Includes: Supplemental data

Journal Articles

Thymic Retention of CD4+CD25 hi +FoxP3+ T Regulatory (Treg) Cells Is Responsible for Peripheral Treg Deficiency and Platelet and Megakaryocyte Destruction in Active Immune Thrombocytopenia (ITP)

John W. Semple, PhD, Simon Gebremeskel, BSc, Rukhsana Aslam, Ph.D., Heyu Ni, John Freedman, MD

Blood (2011) 118 (21): 523.

https://doi.org/10.1182/blood.V118.21.523.523

Published: 2011

Journal Articles

The Functional Role of TLR9 in Human Platelets

Jonathan Noah Thon, Ph.D., Christian G. Peters, Ph.D., Rukhsana Aslam, Ph.D., Jesse Rowley, Ph.D., Andrew S. Weyrich, Ph.D., John W. Semple, PhD, Robert C. Flaumenhaft, MD, PhD, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 366.

https://doi.org/10.1182/blood.V118.21.366.366

Published: 2011

Journal Articles

The Role of Recipient Platelets In the Prevention of Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Yuhan Chen, Michael Kim, Arata Tabuchi, Wolfgang M. Kuebler, MD, PhD, Rukhsana Aslam, PhD, John J. Freedman, MD, FRCPC, John W. Semple, PhD

Blood (2010) 116 (21): 3351.

https://doi.org/10.1182/blood.V116.21.3351.3351

Published: 2010

Journal Articles

Allogeneic Platelet MHC Class I Antigens Prevent CD61 Specific Cytotoxic T Cell (CTL)-Mediated Immune Thrombocytopenia (ITP).

Li Guo, Rukhsana Aslam, Edwin R Speck, Heyu Ni, Ming Hou, John J. Freedman, MD, FRCPC, John W. Semple, PhD

Blood (2010) 116 (21): 3686.

https://doi.org/10.1182/blood.V116.21.3686.3686

Published: 2010

NARROW

Racial Disparities in in-Hospital Outcomes of Venous Thromboembolic Events in Patients with Diffuse Large B-Cell Lymphoma

CD8+ T Cells from Patients with CLL Show Evidence of Granzyme B and Perforin Cytotoxic Capacity, Which Is Enhanced upon Exposure to Exogenous IL2 and/or IL21

Activated CLL B Cells Variably Modulate microRNA-155 Levels in Naïve CD4 + T Cells, and the Direction and Magnitude of microRNA-155 Change Correlates with Th17 Levels and Clinical Course

Extended Survival in CLL Patients Who Discontinued Idelalisib Because of Colitis Correlates with Higher Th17 Levels in Blood and Colon Tissue

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10

Successful Treatment of Thrombocytopenia with Staphylococcal Protein A (PRTX-100) in a Murine Model of Immune Thrombocytopenia (ITP)

Thymic-Derived Tolerizing Dendritic Cells Are up-Regulated upon Treatment with Intravenous Immunoglobulin or Splenectomy in a Murine Model of Immune Thrombocytopenia

Murine Bone Marrow-Derived Megakaryocytes Are Capable of Antigen Cross-Presentation on Major Histocompatibility Class (MHC) I Molecules

C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)

CD20 B Cell Depleting Therapy Is Associated with up-Regulation of CD8 + CD25 high Foxp3 + T Regulatory Cells in a Murine Model of Immune Thrombocytopenia (ITP)

Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia

Megakaryocyte Abnormalities Occur In The Absence Of Cell-Mediated Immunity In a Murine Model Of Passive Immune Thrombocytopenia (ITP)

Human and Murine Immune Thrombocytopenia (ITP) Is Associated with a Peripheral Deficiency of CD4- T Regulatory Cells (Tc-regs)

Thrombopoietin Can Induce Tolerogenic Responses Via the Modulation of Thymic and Splenic T Lymphocyte Populations in a Murine Model of Immune Thrombocytopenia (ITP)

Thymic retention of CD4 + CD25 + FoxP3 + T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia

Thymic Retention of CD4+CD25 hi +FoxP3+ T Regulatory (Treg) Cells Is Responsible for Peripheral Treg Deficiency and Platelet and Megakaryocyte Destruction in Active Immune Thrombocytopenia (ITP)

The Functional Role of TLR9 in Human Platelets

The Role of Recipient Platelets In the Prevention of Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Allogeneic Platelet MHC Class I Antigens Prevent CD61 Specific Cytotoxic T Cell (CTL)-Mediated Immune Thrombocytopenia (ITP).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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