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Yannan Jia
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Journal Articles

Enhancing Macrophage Mediated Phagocytosis in AML: The Complementary Mechanisms of Venetoclax and Azacitidine Combination Therapy

Zhe WANG, Xufeng Chen, Simone Sidoli, Anna Skwarska, Yannan Jia, Lei Yang, Varun Gupta, Shikhar Sharma, Iannis Aifantis, Hussein A. Abbas, Naval Daver, Qi Zhang Tatarata, Marina Konopleva
Journal: Blood
Blood (2024) 144 (Supplement 1): 207.
https://doi.org/10.1182/blood-2024-198057
Published: 2024
Journal Articles

Haploidentical Peripheral Blood Stem Cell Transplantation Improves the Survival of Older Patients with Myeloid Malignancies Under Low-Dose Antithymocyte Globin (ATG)/Post-Cyclophosphamide (PTCy)-Based Regimen for Graft-Versus-Host Disease Prophylaxis

Yannan Jia, Xinxin Xia, Jun Yang, Yu Cai, Yin Tong, Chongmei Huang, Huiying Qiu, Kun Zhou, Ying Zhang, Chang Shen, Liping Wan, Xianmin Song
Journal: Blood
Blood (2024) 144 (Supplement 1): 7357.
https://doi.org/10.1182/blood-2024-201952
Published: 2024
Journal Articles

Efficacy of a Novel BCL-XL Degrader, DT2216, in Preclinical Models of Post-Myeloproliferative Neoplasm Secondary AML

Zhe Wang, Anna Skwarska, Gowri Poigailwar, Sovira Chaudhry, Alba Rodriguez-Meira, Pinpin Sui, Emmanuel Olivier, Yannan Jia, Cassandra L. Ramage, Guangrong Zheng, Alexandra Schurer, Kira Gritsman, Eirini Papapetrou, Kapil N. Bhalla, Daohong Zhou, Adam J Mead, Raajit Rampal, Jeffrey W Tyner, Hussein A. Abbas, Naveen Pemmaraju, Qi Zhang Tatarata, Marina Konopleva
Journal: Blood
Blood (2024) 144 (Supplement 1): 2749.
https://doi.org/10.1182/blood-2024-194031
Published: 2024
Journal Articles

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Yannan Jia, Lina Han, Cassandra L Ramage, Connie C. Weng, Lei Yang, Simona Colla, Helen Ma, Weiguo Zhang, Michael Andreeff, Naval Daver, Nitin Jain, Naveen Pemmaraju, Kapil N. Bhalla, Satu Mustjoki, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Qi Zhang, Marina Konopleva
Journal: Blood
Blood (2022) 140 (Supplement 1): 3347–3349.
https://doi.org/10.1182/blood-2022-164541
Published: 2022
Journal Articles

FLT3 Inhibitors Upregulate CXCR4 and E-Selectin Ligands and CD44 Via ERK Suppression in AML Cells, and Blockade of CXCR4 and E-Selectin Signaling with GMI-1359 Overcomes AML Resistance to Quizartinib in Vitro and In Vivo

Yannan Jia, Mahesh Basyal, Lauren B Ostermann, Kyung Hee Chang, Qi Zhang, William E. Fogler, John L. Magnani, Marina Konopleva, Weiguo Zhang, Michael Andreeff
Journal: Blood
Blood (2021) 138 (Supplement 1): 1171.
https://doi.org/10.1182/blood-2021-146573
Published: 2021
Journal Articles

Combined Blockade of CD47-Sirpa Interaction By 5F9 (Magrolimab) and Azacitidine/Venetoclax Therapy Facilitates Macrophage-Mediated Anti-Leukemia Efficacy in AML Pre-Clinical Models

Yannan Jia, Qi Zhang, Connie Weng, Cassandra L Ramage, Yuki Nishida, Mark Chao, Roy Louis Maute, Shelley Herbrich, Weiguo Zhang, Michael Andreeff, Naval Daver, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 510.
https://doi.org/10.1182/blood-2021-147479
Published: 2021
Journal Articles

Targeting BCL-XL and BCL-2 By Protac 753B Effectively Eliminates AML Cells and Enhances Efficacy of Chemotherapy By Targeting Senescent Cells

Yannan Jia, Qi Zhang, Weiguo Zhang, Michael Andreeff, Nitin Jain, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 2230.
https://doi.org/10.1182/blood-2021-147535
Published: 2021
Journal Articles

Co-Targeting E-Selectin/CXCR4 with GMI-1359 Facilitates AML Stem Cell Mobilization and Protects BM Niches from Anti-Leukemia Therapy

Kyung Hee Chang, Tomasz Zal, Mahesh Basyal, Lauren Ostermann, Muharrem Muftuoglu, Po Yee Mak, Yannan Jia, Wenjing Tao, Malgorzata Anna Zal, William E. Fogler, John L. Magnani, Weiguo Zhang, Bing Z Carter, Michael Andreeff
Journal: Blood
Blood (2021) 138 (Supplement 1): 3348.
https://doi.org/10.1182/blood-2021-153661
Published: 2021
Journal Articles

Combined Blockage of E-Selectin and CXCR4 (GMI-1359) Enhances Anti-Leukemia Effect of FLT3 Inhibition (Sorafenib) and Protects Hematopoiesis in Pre-Clinical AML Models

Weiguo Zhang, MD PhD, Kyung Hee Chang, PhD, Mahesh Basyal, BS, Yannan Jia, Lauren B Ostermann, BS, William E. Fogler, PhD, John L. Magnani, PhD, M Anna Zal, BS., MS, Tomasz Zal, PhDMSc, Michael Andreeff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-140984
Published: 2020
Journal Articles

Machine Leaning Algorithm on Chemotherapeutic Drug Resistance Related Gene Classifier in Acute Myeloid Leukemia

Yang Song, MD, Yannan Jia, Guangji Zhang, Shuning Wei, Yan Li, MD, Yimin Hu, Qishan Hao, Zhe Wang, Qiuyun Fang, Zheng Tian, BS, Shangzhu Li, Min Wang, MD, Jianxiang Wang, MD, Yingchang Mi
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-142194
Published: 2020