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Journal Articles

Exploring the Potential of JAK1/2 Inhibitor Ruxolitinib with Reduced Intensity Hematopoietic Cell Transplantation (HCT) for Myelofibrosis: Stage I Results of a Prospective Trial Conducted through the Myeloproliferative Disorders - Research Consortium (MPD-RC)

Blood (2016) 128 (22): 1126.

https://doi.org/10.1182/blood.V128.22.1126.1126

Published: 2016

Journal Articles

Relationship of JAK2 V617F Allelic Burden (AB) to Demographics, Disease Characteristics, and Response to Therapy in Persist-1, a Randomized Phase III Study of Pacritinib (PAC) Versus Best Available Therapy (BAT) in Patients (pts) with Primary and Secondary Myelofibrosis (MF)

Alessandro M. Vannucchi, Adam Mead, Miklos Egyed, Anita Szoke, Aleksandr Suvorov, Andrew Perkins, Jiri Mayer, Peter Ganly, Harry C. Schouten, Patrizia Tosi, Charles Michael Farber, Pierre Zachee, Jean-Jacques Kiladjian, Jyoti Nangalia, James P. Dean, Huafeng Zhou, Jack W. Singer, Ruben A. Mesa, Claire N. Harrison

Blood (2016) 128 (22): 3131.

https://doi.org/10.1182/blood.V128.22.3131.3131

Published: 2016

Journal Articles

Interim Analysis of the Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia

John O. Mascarenhas, MD MS, Josef T. Prchal, MD, Alessandro Rambaldi, MD, Ruben A. Mesa, MD, Dmitriy Berenzon, MD, Abdulraheem Yacoub, MD, Claire N. Harrison, DM, FRCP, FRCPath, Mary Frances McMullin, MD, Alessandro M. Vannucchi, MD PhD, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Casey L O'Connell, MD, Jean-Jacques Kiladjian, MD PhD, Adam Mead, MD PhD, Elliott F. Winton, MD, David S. Leibowitz, MD, Valerio De Stefano, Murat O. Arcasoy, MD, Craig M. Kessler, MD, Rosalind Catchatorian, Damiano Rondelli, MD, Richard T. Silver, MD, Ellen K. Ritchie, MD, Arnon Nagler, Marina Kremyanskaya, MD PhD, Richard F. Schlenk, MD, Rona Singer Weinberg, PhD, Mohamed E Salama, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Jill Kleczko, Heidi E. Kosiorek, MS, Tiziano Barbui, MD, Amylou C. Dueck, PhD, Ronald Hoffman, MD

Blood (2016) 128 (22): 479.

https://doi.org/10.1182/blood.V128.22.479.479

Published: 2016

Journal Articles

Impact on MPN Symptoms and Quality of Life of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia: Interim Analysis Results of Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial

Ruben A. Mesa, MD, Ronald Hoffman, MD, Heidi E. Kosiorek, MS, Josef T. Prchal, MD, Claire N. Harrison, DM, FRCP, FRCPath, Mary Frances McMullin, MD, Abdulraheem Yacoub, MD, Alessandro Rambaldi, MD, Dmitriy Berenzon, MD, Alessandro M. Vannucchi, MD PhD, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Casey L O'Connell, MD, Jean-Jacques Kiladjian, MD PhD, Adam Mead, MD PhD, Elliott F. Winton, MD, David S. Leibowitz, MD, Valerio De Stefano, MD, Murat O. Arcasoy, MD, Craig M. Kessler, MD, Rosalind Catchatorian, Damiano Rondelli, MD, Richard T. Silver, MD, Ellen K. Ritchie, MD, Arnon Nagler, Marina Kremyanskaya, MD PhD, Richard F. Schlenk, MD, Rona Singer Weinberg, PhD, Mohamed E Salama, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Alicia Orellana, MD, Tiziano Barbui, MD, Amylou C. Dueck, PhD, John O. Mascarenhas, MD MS

Blood (2016) 128 (22): 4271.

https://doi.org/10.1182/blood.V128.22.4271.4271

Published: 2016

Journal Articles

Correlation Between Treatment Outcomes, Baseline Characteristics and Molecular Responses in the Majic Study Which Compared Ruxolitinib to Best Available Therapy in Essential Thrombocythemia

Blood (2016) 128 (22): 1929.

https://doi.org/10.1182/blood.V128.22.1929.1929

Published: 2016

Journal Articles

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

Christopher Booth, Nikolas Barkas, Wen Hao Neo, Elizabeth Soilleux, Hanane Boukarabila, Alice Giustacchini, Thomas Milne, Neil Ashley, Joana Carrelha, Lauren Jamieson, Deborah Atkinson, Tiphaine Bouriez-Jones, Sten Eirik Jacobsen, Adam Mead

Blood (2015) 126 (23): 846.

https://doi.org/10.1182/blood.V126.23.846.846

Published: 2015

Journal Articles

Analysis of Outcomes By Patient Subgroups in Patients with Myelofibrosis Treated with Pacritinib Vs Best Available Therapy (BAT) in the Phase III Persist-1 Trial

Alessandro M. Vannucchi, Ruben A. Mesa, Francisco Cervantes, Ritam Prasad, Janos Jakucs, Anna Elinder, Christian Recher, MDPhD, Peter A. te Boekhorst, Steven Knapper, Tim Somervaille, James P. Dean, Tanya Granston, Adam Mead, Claire N. Harrison

Blood (2015) 126 (23): 58.

https://doi.org/10.1182/blood.V126.23.58.58

Published: 2015

Journal Articles

Relationship Between Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) and Efficacy in Patients with Myelofibrosis in the Phase III Persist-1 Trial of Pacritinib Vs. Best Available Therapy (BAT)

Ruben A. Mesa, Claire N. Harrison, Francisco Cervantes, James P. Dean, Lixia Wang, Tanya Granston, Yoojung Yang, Alessandro M. Vannucchi, Adam Mead

Blood (2015) 126 (23): 1609.

https://doi.org/10.1182/blood.V126.23.1609.1609

Published: 2015

Journal Articles

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Alice Giustacchini, Supat Thongjuea, Petter S. Woll, PhD, Paul Sopp, Ana Duenas Perez, Nikolaos Barkas, Christopher Booth, Ruggiero Norfo, Sally-Ann Clark, Lauren Jamieson, Sten Eirik Jacobsen, Adam Mead

Blood (2015) 126 (23): 13.

https://doi.org/10.1182/blood.V126.23.13.13

Published: 2015

Journal Articles

Development and Evaluation of the Clinical Utility of a Next Generation Sequencing (NGS) Tool for Myeloid Disorders

Angela Hamblin, MDPhD, Adam Burns, BSc, Christopher Tham, BA, Ruth Clifford, MD, Pauline Robbe, MSc, Adele Timbs, MSc, Joanne Mason, PhD, Helene Dreau, MSc, Andreas Weller, PhD, Puthen Jithesh, PhD, Olivia Fox, BSc, Melody Tabiner, MA, Adam Mead, MDPhD, Andrew Peniket, MD, Paresh Vyas, MDPhD, Shirley Henderson, PhD, Anna Schuh, MDPhD

Blood (2014) 124 (21): 2373.

https://doi.org/10.1182/blood.V124.21.2373.2373

Published: 2014

Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Blood (2014) 124 (21): 15.

https://doi.org/10.1182/blood.V124.21.15.15

Published: 2014

Journal Articles

Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML

Onima Chowdhury, MD PhD, Petter S Woll, PhD, Una Kjällquist, PhD, Helen Doolittle, MD, Rikard Erlandsson, PhD, Kristina Anderson, MD PhD, Ingunn Dybedal, MD PhD, Adam Mead, MDPhD, Sally-Ann Clark, PhD, Mette S. Holm, MD PhD, Peter Hokland, MD DMSc, Lars Nilsson, MD PhD, Sten Linnarsson, PhD, Eva Hellstrom-Lindberg, MD PhD, Sten Eirik W Jacobsen, MD PhD

Blood (2014) 124 (21): 1896.

https://doi.org/10.1182/blood.V124.21.1896.1896

Published: 2014

Journal Articles

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia

Toby Eyre, Claire J. Schwab, Ross Kinstrie, Ann Keen McGuire, Jen Strefford, Andrew Peniket, Adam Mead, Tim Littlewood, Tessa L. Holyoake, Mhairi Copland, Anthony V. Moorman, Christine J. Harrison, Paresh Vyas

Blood (2012) 120 (22): 4441–4443.

https://doi.org/10.1182/blood-2012-09-456517

Published: 2012

Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Blood (2010) 116 (21): 91.

https://doi.org/10.1182/blood.V116.21.91.91

Published: 2010

Journal Articles

Favourable Prognosis Associated with FLT3 Tyrosine Kinase Domain Mutations in AML in Contrast to the Adverse Outcome Associated with Internal Tandem Duplications.

Adam Mead, David Linch, Robert Hills, Keith Wheatley, Alan Burnett, Rosemary Gale

Blood (2005) 106 (11): 334.

https://doi.org/10.1182/blood.V106.11.334.334

Published: 2005

NARROW

Exploring the Potential of JAK1/2 Inhibitor Ruxolitinib with Reduced Intensity Hematopoietic Cell Transplantation (HCT) for Myelofibrosis: Stage I Results of a Prospective Trial Conducted through the Myeloproliferative Disorders - Research Consortium (MPD-RC)

Relationship of JAK2 V617F Allelic Burden (AB) to Demographics, Disease Characteristics, and Response to Therapy in Persist-1, a Randomized Phase III Study of Pacritinib (PAC) Versus Best Available Therapy (BAT) in Patients (pts) with Primary and Secondary Myelofibrosis (MF)

Interim Analysis of the Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia

Impact on MPN Symptoms and Quality of Life of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia: Interim Analysis Results of Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial

Correlation Between Treatment Outcomes, Baseline Characteristics and Molecular Responses in the Majic Study Which Compared Ruxolitinib to Best Available Therapy in Essential Thrombocythemia

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

Analysis of Outcomes By Patient Subgroups in Patients with Myelofibrosis Treated with Pacritinib Vs Best Available Therapy (BAT) in the Phase III Persist-1 Trial

Relationship Between Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) and Efficacy in Patients with Myelofibrosis in the Phase III Persist-1 Trial of Pacritinib Vs. Best Available Therapy (BAT)

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Development and Evaluation of the Clinical Utility of a Next Generation Sequencing (NGS) Tool for Myeloid Disorders

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Favourable Prognosis Associated with FLT3 Tyrosine Kinase Domain Mutations in AML in Contrast to the Adverse Outcome Associated with Internal Tandem Duplications.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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