1-20 of 21
Adam Mead
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Fedora preliminary analysis of a Phase II study evaluating the tolerability, safety and activity of fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis.

Free
Mary Frances McMullin, Fitsum Ghebretinsea, Rebecca Boucher, Sebastian Francis, Gillian Horne, Hayder Hussein, Steve Knapper, Donal McLornan, Srinivasan Narayanan, Jennifer O Sullivan, Tim Somervaille, Chun Teh, Frances Wadelin, Chhaya Sankhalpara, Emily Yafai, Catherine Thomas, Rupen Hargreaves, Nawshad Hayder, Graham Mcllroy, Claire Harrison, Adam Mead
Journal: Blood
Blood (2025) 146 (Supplement 1): 486.
https://doi.org/10.1182/blood-2025-486
Published: 2025
Journal Articles

Backtracking the cellular origins of ETV6::RUNX1 childhood acute lymphoblastic leukemia in cord blood (ReCord study)

Free
Adam de Smith, Natalina Elliott, Amiya Tucker, Tanxin Liu, Nawara Ahsan, Adam Mead, Irene Roberts, Joseph Wiemels, Michelle Roesler, Logan Spector, Anindita Roy
Journal: Blood
Blood (2025) 146 (Supplement 1): 3368.
https://doi.org/10.1182/blood-2025-3368
Published: 2025
Journal Articles

Evaluation of the novel TMPRSS6 antisense inhibitor sapablursen for treatment of polycythemia vera: Results of the imprssion clinical trial

Free
Jeanne Palmer, Jonathan How, Prithviraj Bose, Pankit Vachhani, Adam Mead, Jonathan Sillar, Aaron Gerds, Angela Fleischman, Caitlin O'Neill, Ross Baker, Ronald Hoffman, Shiangtung Jung, Jon Ruckle, Keyvan Yousefi, Sanjay Bhanot, Terry Barrett, Ruben Mesa
Journal: Blood
Blood (2025) 146 (Supplement 1): 82.
https://doi.org/10.1182/blood-2025-82
Published: 2025
Journal Articles

Genome editing for treatment of JAK2 V617F-driven myeloproliferative neoplasms

Free
Roman Doll, Yuqi Shen, Zoë Wong, Ramy Slama, Maria Greco, Lai Cheng, Eleni Louka, Weijiao Zhang, Yavor Bozhilov, Joseph Hamley, Adam Wilkinson, Bethan Psaila, Adam Mead, James Davies
Journal: Blood
Blood (2025) 146 (Supplement 1): 68.
https://doi.org/10.1182/blood-2025-68
Published: 2025
Journal Articles

Multi-endpoint AI morphology model (MEAM) enhances risk prediction for vascular events and disease progression in MPNs

Free
Xuezi Hu, Alan Aberdeen, Sharon Ruane, Rosalin Cooper, Timothy Ebsworth, Sanam Loghavi, David Ross, Diana Iarossi, Markus Tiemann, Amin Turki, Andrew Sung, Mingyi Chen, Zijun Xu-Monette, Ken H. Young, Anna Godfrey, Jyoti Nangalia, Joanna Baxter, Anthony Green, Mary Frances McMullin, Adam Mead, Claire Harrison, Jens Rittscher, Korsuk Sirinukunwattana, Daniel Royston
Journal: Blood
Blood (2025) 146 (Supplement 1): 5599.
https://doi.org/10.1182/blood-2025-5599
Published: 2025
Journal Articles

Interim analysis of promise, a clinical study combining the BET inhibitor OPN-2853 with ruxolitinib in patients with advanced myelofibrosis experiencing an inadequate response to ruxolitinib

Free
Adam Mead, Bethan Psaila, Rebecca Boucher, Jiayi Wang, Rebecca Collings, Rebecca Record, Zsofia Nagy, Aishah Begum, Steve Knapper, Frances Wadelin, Manish Jain, Jenny O'Nions, Mary Frances McMullin, Sebastian Francis, Patrick Harrington, Srinivasan Narayanan, Kerry Inokuchi, Jackie Walling, Brain Huntley, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 3794.
https://doi.org/10.1182/blood-2025-3794
Published: 2025
Journal Articles

Impact on MPN Symptoms and Quality of Life of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia: Interim Analysis Results of Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial

Free
Ruben A. Mesa, MD, Ronald Hoffman, MD, Heidi E. Kosiorek, MS, Josef T. Prchal, MD, Claire N. Harrison, DM, FRCP, FRCPath, Mary Frances McMullin, MD, Abdulraheem Yacoub, MD, Alessandro Rambaldi, MD, Dmitriy Berenzon, MD, Alessandro M. Vannucchi, MD PhD, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Casey L O'Connell, MD, Jean-Jacques Kiladjian, MD PhD, Adam Mead, MD PhD, Elliott F. Winton, MD, David S. Leibowitz, MD, Valerio De Stefano, MD, Murat O. Arcasoy, MD, Craig M. Kessler, MD, Rosalind Catchatorian, Damiano Rondelli, MD, Richard T. Silver, MD, Ellen K. Ritchie, MD, Arnon Nagler, Marina Kremyanskaya, MD PhD, Richard F. Schlenk, MD, Rona Singer Weinberg, PhD, Mohamed E Salama, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Alicia Orellana, MD, Tiziano Barbui, MD, Amylou C. Dueck, PhD, John O. Mascarenhas, MD MS
Journal: Blood
Blood (2016) 128 (22): 4271.
https://doi.org/10.1182/blood.V128.22.4271.4271
Published: 2016
Journal Articles

Interim Analysis of the Myeloproliferative Disorders Research Consortium (MPD-RC) 112 Global Phase III Trial of Front Line Pegylated Interferon Alpha-2a Vs. Hydroxyurea in High Risk Polycythemia Vera and Essential Thrombocythemia

Free
John O. Mascarenhas, MD MS, Josef T. Prchal, MD, Alessandro Rambaldi, MD, Ruben A. Mesa, MD, Dmitriy Berenzon, MD, Abdulraheem Yacoub, MD, Claire N. Harrison, DM, FRCP, FRCPath, Mary Frances McMullin, MD, Alessandro M. Vannucchi, MD PhD, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Casey L O'Connell, MD, Jean-Jacques Kiladjian, MD PhD, Adam Mead, MD PhD, Elliott F. Winton, MD, David S. Leibowitz, MD, Valerio De Stefano, Murat O. Arcasoy, MD, Craig M. Kessler, MD, Rosalind Catchatorian, Damiano Rondelli, MD, Richard T. Silver, MD, Ellen K. Ritchie, MD, Arnon Nagler, Marina Kremyanskaya, MD PhD, Richard F. Schlenk, MD, Rona Singer Weinberg, PhD, Mohamed E Salama, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Jill Kleczko, Heidi E. Kosiorek, MS, Tiziano Barbui, MD, Amylou C. Dueck, PhD, Ronald Hoffman, MD
Journal: Blood
Blood (2016) 128 (22): 479.
https://doi.org/10.1182/blood.V128.22.479.479
Published: 2016
Journal Articles

Relationship of JAK2 V617F Allelic Burden (AB) to Demographics, Disease Characteristics, and Response to Therapy in Persist-1, a Randomized Phase III Study of Pacritinib (PAC) Versus Best Available Therapy (BAT) in Patients (pts) with Primary and Secondary Myelofibrosis (MF)

Free
Alessandro M. Vannucchi, Adam Mead, Miklos Egyed, Anita Szoke, Aleksandr Suvorov, Andrew Perkins, Jiri Mayer, Peter Ganly, Harry C. Schouten, Patrizia Tosi, Charles Michael Farber, Pierre Zachee, Jean-Jacques Kiladjian, Jyoti Nangalia, James P. Dean, Huafeng Zhou, Jack W. Singer, Ruben A. Mesa, Claire N. Harrison
Journal: Blood
Blood (2016) 128 (22): 3131.
https://doi.org/10.1182/blood.V128.22.3131.3131
Published: 2016
Journal Articles

Correlation Between Treatment Outcomes, Baseline Characteristics and Molecular Responses in the Majic Study Which Compared Ruxolitinib to Best Available Therapy in Essential Thrombocythemia

Free
Claire N. Harrison, DM, FRCP, FRCPath, Adam Mead, MD PhD, Sonia Fox, Anesh Panchal, BSc, MSc, Christina Yap, BSc, MSc, PhD, Aimee E Houlton, BSc, MSc, Samah Aliman, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Marion Wood, FRCP, FRCPath, Frederick Chen, MBBS, PhD FRCPath, Jason Coppell, Nicki Panoskaltsis, MD PhD, Steven Knapper, Sahra Ali, FRCPath, Angela Hamblin, MDPhD, Robyn M. Scherber, MD MPH, Holly Geyer, MD, Allison H Scotch, MD MPH, Amylou Constance Dueck, PhD, Nicholas CP Cross, PhD, Ruben A. Mesa, MD, Mary Frances McMullin, MD
Journal: Blood
Blood (2016) 128 (22): 1929.
https://doi.org/10.1182/blood.V128.22.1929.1929
Published: 2016
Journal Articles

Exploring the Potential of JAK1/2 Inhibitor Ruxolitinib with Reduced Intensity Hematopoietic Cell Transplantation (HCT) for Myelofibrosis: Stage I Results of a Prospective Trial Conducted through the Myeloproliferative Disorders - Research Consortium (MPD-RC)

Free
Vikas Gupta, MD, Heidi E. Kosiorek, MS, Rebecca B Klisovic, MD, John P. Galvin, MD MPH, Dmitriy Berenzon, MD, Abdulraheem Yacoub, MD, Ruben A. Mesa, MD, Gianni Tognoni, Giuseppe Prosperini, Alessandra Di Lelio, Eliseo Serone, Lorenzo Marfisi, Alicia Orellano, Lee Potiphar, Mohamed E Salama, MD, Rona Singer Weinberg, PhD, Amylou C. Dueck, PhD, Adam Mead, MD PhD, John O. Mascarenhas, MD MS, Ronald Hoffman, MD
Journal: Blood
Blood (2016) 128 (22): 1126.
https://doi.org/10.1182/blood.V128.22.1126.1126
Published: 2016
Journal Articles

Analysis of Outcomes By Patient Subgroups in Patients with Myelofibrosis Treated with Pacritinib Vs Best Available Therapy (BAT) in the Phase III Persist-1 Trial

Free
Alessandro M. Vannucchi, Ruben A. Mesa, Francisco Cervantes, Ritam Prasad, Janos Jakucs, Anna Elinder, Christian Recher, MDPhD, Peter A. te Boekhorst, Steven Knapper, Tim Somervaille, James P. Dean, Tanya Granston, Adam Mead, Claire N. Harrison
Journal: Blood
Blood (2015) 126 (23): 58.
https://doi.org/10.1182/blood.V126.23.58.58
Published: 2015
Journal Articles

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

Free
Christopher Booth, Nikolas Barkas, Wen Hao Neo, Elizabeth Soilleux, Hanane Boukarabila, Alice Giustacchini, Thomas Milne, Neil Ashley, Joana Carrelha, Lauren Jamieson, Deborah Atkinson, Tiphaine Bouriez-Jones, Sten Eirik Jacobsen, Adam Mead
Journal: Blood
Blood (2015) 126 (23): 846.
https://doi.org/10.1182/blood.V126.23.846.846
Published: 2015
Journal Articles

Relationship Between Patient-Reported Outcomes (PROs) and Health-Related Quality of Life (HRQoL) and Efficacy in Patients with Myelofibrosis in the Phase III Persist-1 Trial of Pacritinib Vs. Best Available Therapy (BAT)

Free
Ruben A. Mesa, Claire N. Harrison, Francisco Cervantes, James P. Dean, Lixia Wang, Tanya Granston, Yoojung Yang, Alessandro M. Vannucchi, Adam Mead
Journal: Blood
Blood (2015) 126 (23): 1609.
https://doi.org/10.1182/blood.V126.23.1609.1609
Published: 2015
Journal Articles

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Free
Alice Giustacchini, Supat Thongjuea, Petter S. Woll, PhD, Paul Sopp, Ana Duenas Perez, Nikolaos Barkas, Christopher Booth, Ruggiero Norfo, Sally-Ann Clark, Lauren Jamieson, Sten Eirik Jacobsen, Adam Mead
Journal: Blood
Blood (2015) 126 (23): 13.
https://doi.org/10.1182/blood.V126.23.13.13
Published: 2015
Journal Articles

Development and Evaluation of the Clinical Utility of a Next Generation Sequencing (NGS) Tool for Myeloid Disorders

Free
Angela Hamblin, MDPhD, Adam Burns, BSc, Christopher Tham, BA, Ruth Clifford, MD, Pauline Robbe, MSc, Adele Timbs, MSc, Joanne Mason, PhD, Helene Dreau, MSc, Andreas Weller, PhD, Puthen Jithesh, PhD, Olivia Fox, BSc, Melody Tabiner, MA, Adam Mead, MDPhD, Andrew Peniket, MD, Paresh Vyas, MDPhD, Shirley Henderson, PhD, Anna Schuh, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2373.
https://doi.org/10.1182/blood.V124.21.2373.2373
Published: 2014
Journal Articles

Characterisation of the Stem and Progenitor Cell Hierarchy in Patients with CMML

Free
Onima Chowdhury, MD PhD, Petter S Woll, PhD, Una Kjällquist, PhD, Helen Doolittle, MD, Rikard Erlandsson, PhD, Kristina Anderson, MD PhD, Ingunn Dybedal, MD PhD, Adam Mead, MDPhD, Sally-Ann Clark, PhD, Mette S. Holm, MD PhD, Peter Hokland, MD DMSc, Lars Nilsson, MD PhD, Sten Linnarsson, PhD, Eva Hellstrom-Lindberg, MD PhD, Sten Eirik W Jacobsen, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1896.
https://doi.org/10.1182/blood.V124.21.1896.1896
Published: 2014
Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Free
Lynn Quek, Georg Otto, Catherine Garnett, Ludovic Lhermitte, I-Jun Lau, Dimitris Karamitros, Jessica Doondeea, Batchimeg Usukhbayar, Nicolas Goardon, Adam Ivey, Yisu Gu, Christopher G Allen, Rosemary E Gale, Benjamin Davies, Alexander Sternberg, Sally Killick, Hannah Hunter, Paul Cahalin, Andrew Price, Andrew Carr, Mike Griffiths, Paul Virgo, Stephen Mackinnon, David Grimwade, Sylvie D Freeman, Nigel Russell, Charles Craddock, MDPhD, Adam Mead, MDPhD, Andrew Peniket, MD, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2014) 124 (21): 15.
https://doi.org/10.1182/blood.V124.21.15.15
Published: 2014
Journal Articles

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia

Free
Toby Eyre, Claire J. Schwab, Ross Kinstrie, Ann Keen McGuire, Jen Strefford, Andrew Peniket, Adam Mead, Tim Littlewood, Tessa L. Holyoake, Mhairi Copland, Anthony V. Moorman, Christine J. Harrison, Paresh Vyas
Journal: Blood
Blood (2012) 120 (22): 4441–4443.
https://doi.org/10.1182/blood-2012-09-456517
Published: 2012
Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Free
Nicolas Goardon, Emmanuele Marchi, Lynn Quek, Anna Schuh, Petter Woll, Adam Mead, Kate Alford, Amanda Gilkes, Kheira Beldjord, David Bowen, Graham Standen, Sally Killick, Hannah Hunter, Steven Knapper, Lisa Robinson, Alex Sternberg, James D Cavenagh, Paul Virgo, Mike Griffiths, Elizabeth A. Macintyre, PhD, FRCP, FRCPath, Charles Craddock, Alan Burnett, Tariq Enver, PhD, Sten Eirik W Jacobsen, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2010) 116 (21): 91.
https://doi.org/10.1182/blood.V116.21.91.91
Published: 2010