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Thomas Milne
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Journal Articles

Oncogenic Feedback Activation Between BCL6 and MLL Promotes Malignant Transformation in MLL -RearrangedAcute Lymphoblastic Leukemia

Christian Hurtz, PhD, Lai N Chan, PhD, Erica Ballabio, MD, Cheryl L. Willman, William L. Carroll, MD, Scott A. Armstrong, MD PhD, Patricia Ernst, PhD, Ari Melnick, MD, Thomas Milne, PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 907.
https://doi.org/10.1182/blood.V128.22.907.907
Published: 2016
Journal Articles

The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding

Shan Lin, Anetta Ptasinska, PhD, Salam Adli Assi, Jon Kerry, Ruhikanta A. Meetei, PhD, Roger T. Luo, PhD, Michael J. Thirman, MD, Thomas Milne, PhD, Constanze Bonifer, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2016) 128 (22): 576.
https://doi.org/10.1182/blood.V128.22.576.576
Published: 2016
Journal Articles

B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling

Lai N Chan, PhD, Zhengshan Chen, PhDMD, Daniel Braas, PhD, Huimin Geng, PhD, Christian Hurtz, PhD, Seyedmehdi Shojaee, PhD, Valeria Cazzaniga, PhD, Carina Ng, Thomas Ernst, MD, Andreas Hochhaus, MD, Steven M Kornblau, PhD, Giovanni Cazzaniga, PhD, Grace Liu, PhD, Thomas Milne, PhD, H. Phillip Koeffler, MD, Scott A. Armstrong, MD PhD, Ross Alexander Dickins, PhD, Keith R Yamamoto, PhD, Thomas G Graeber, PhD, Markus Muschen, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1255.
https://doi.org/10.1182/blood.V126.23.1255.1255
Published: 2015
Journal Articles

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

Christopher Booth, Nikolas Barkas, Wen Hao Neo, Elizabeth Soilleux, Hanane Boukarabila, Alice Giustacchini, Thomas Milne, Neil Ashley, Joana Carrelha, Lauren Jamieson, Deborah Atkinson, Tiphaine Bouriez-Jones, Sten Eirik Jacobsen, Adam Mead
Journal: Blood
Blood (2015) 126 (23): 846.
https://doi.org/10.1182/blood.V126.23.846.846
Published: 2015
Journal Articles

Self-Enforcing Feedback Activation Between BCL6 and Tonic Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia

Huimin Geng, PhD, Christian Hurtz, PhD, Dirk Baumjohann, PhD, Zhengshan Chen, MD PhD, Wei-Yi Chen, PhD, Erica Ballabio, PhD, Gang Xiao, PhD, Jae-Woong Lee, PhD, Anne Deucher, MDPhD, Zhongxia Qi, PhD, Chuanxin Huang, PhD, Rahul Nahar, PhD, Soo-mi Kweon, PhD, Seyedmehdi Shojaee, PhD, Lai N Chan, PhD, Jingwei Yu, PhD, Jeffrey W. Tyner, PhD, Bill H Chang, MD PhD, Steven M. Kornblau, MD, Janetta Jacoba Bijl, PhD, B. Hilda Ye, PhD, Elisabeth Paietta, PhD, Ari Melnick, MD, Robert Roeder, PhD, Stephen Hunger, MD, Mignon Loh, MD, Thomas Milne, PhD, Markus Muschen, MD PhD
Journal: Blood
Blood (2014) 124 (21): 284.
https://doi.org/10.1182/blood.V124.21.284.284
Published: 2014
Journal Articles

Identification Of BCL6 As a Therapeutic Target In MLL-Rearranged ALL

Christian Hurtz, PhD, Huimin Geng, PhD, Erica Ballabio, PhD, Gang Xiao, PhD, Carina Ng, Behzad Kharabi Masouleh, MD, Cheryl L. Willman, MD, Scott A. Armstrong, MD, PhD, Thomas Milne, PhD, Ari Melnick, MD, Markus Muschen
Journal: Blood
Blood (2013) 122 (21): 72.
https://doi.org/10.1182/blood.V122.21.72.72
Published: 2013
Journal Articles

Targeting Pre-B Cell Receptor and BCL6 In TCF3-PBX1 B-Lineage Acute Lymphoblastic Leukemia

Huimin Geng, PhD, Christian Hurtz, PhD, Zhengshan Chen, MD, PhD, Wei-Yi Chen, PhD, Erica Ballabio, PhD, Gang Xiao, PhD, Soo-mi Kweon, PhD, Rahul Nahar, PhD, Seyedmehdi Sojaee, PhD, Lai N. Chan, PhD, Behzad Kharabi Masouleh, MD, David B. Sykes, MD, PhD, Ari Melnick, MD, Robert Roeder, PhD, Thomas Milne, PhD, Markus Muschen, MD
Journal: Blood
Blood (2013) 122 (21): 349.
https://doi.org/10.1182/blood.V122.21.349.349
Published: 2013