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Gianna Bloye
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Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

A Non-Canonical Lymphoblast in Refractory Childhood T-Cell Acute Lymphoblastic Leukemia

Bram S.J. Lim, Holly J. Whitfield, Mi K. Trinh, Gianna Bloye, Rebecca Thomas, Nathaniel D. Anderson, Anna Wenger, Angus Hodder, Taryn D. Treger, Henry Lee-Six, Tim H.H. Coorens, Conor Parks, Toochi Ogbonnah, Petri Pölönen, Charles G. Mullighan, David T. Teachey, Melanie M Hagleitner, Lennart A. Kester, Frank N. van Leeuwen, Gordon Beattie, Marc R. Mansour, Owen Williams, Jack Bartram, Stuart Adams, Laura Jardine, Sam Behjati, David O'Connor
Journal: Blood
Blood (2024) 144 (Supplement 1): 2830.
https://doi.org/10.1182/blood-2024-198354
Published: 2024
Journal Articles

Noncoding mutations drive persistence of a founder preleukemic clone which initiates late relapse in T-ALL

David O’Connor, Jose Espejo Valle-Inclán, Lucia Conde, Gianna Bloye, Sunniyat Rahman, Joana R. Costa, Jack Bartram, Stuart Adams, Gary Wright, Hillary Elrick, Kerry Wall, Sara Dyer, Christopher Howell, Galina Jigoulina, Javier Herrero, Isidro Cortes-Ciriano, Anthony V. Moorman, Marc R. Mansour
Journal: Blood
Blood (2024) 143 (10): 933–937.
https://doi.org/10.1182/blood.2023021906
Published: 2024
Includes: Supplemental data
Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Sunniyat Rahman, Nadine Farah, Jonas Demeulemeester, Joana R Costa, Gianna Bloye, David O'Connor, Rachael Pocock, Adam Turna, SooWah Lee, Adele K. Fielding, Juliette Roels, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Alejandro Gutierrez, Michelle A Kelliher, Simone Riva, Jim R. Hughes, James O.J. Davies, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1009–1010.
https://doi.org/10.1182/blood-2022-162930
Published: 2022
Journal Articles

The Clinico-Genomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

David O'Connor, Jonas Demeulemeester, Lucia Conde, Amy A. Kirkwood, Kent Fung, Foteini Papaleonidopoulou, Gianna Bloye, Nadine Farah, Sunniyat Rahman, Jeremy Hancock, Caroline Bateman, Sarah Inglott, Jon Mee, Javier Herrero, Peter Van Loo, Anthony V. Moorman, Ajay Vora, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1720–1721.
https://doi.org/10.1182/blood-2022-165308
Published: 2022