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Jonas Demeulemeester
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Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

Allele-Specific Expression of Leukemia Genes Is Associated with Pathogenicity in Poor Risk AML

Jiexin Zheng, Findlay Bewicke-Copley, Carlo Vermeulen, Pedro Casado, Fadimana Kaya, Jonas Demeulemeester, Molly Guscott, Szilvia Krizsán, Sam Benkwitz-Bedford, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Doriana Di Bella, John G. Gribben, James Cavenagh, Peter Van Loo, Sarah McClelland, Csaba Bödör, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro R Cutillas, Jun Wang, Jeroen De Ridder, Jude Fitzgibbon, Ana Rio-Machin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1389.
https://doi.org/10.1182/blood-2023-184516
Published: 2023
Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Sunniyat Rahman, Nadine Farah, Jonas Demeulemeester, Joana R Costa, Gianna Bloye, David O'Connor, Rachael Pocock, Adam Turna, SooWah Lee, Adele K. Fielding, Juliette Roels, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Alejandro Gutierrez, Michelle A Kelliher, Simone Riva, Jim R. Hughes, James O.J. Davies, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1009–1010.
https://doi.org/10.1182/blood-2022-162930
Published: 2022
Journal Articles

The Clinico-Genomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

David O'Connor, Jonas Demeulemeester, Lucia Conde, Amy A. Kirkwood, Kent Fung, Foteini Papaleonidopoulou, Gianna Bloye, Nadine Farah, Sunniyat Rahman, Jeremy Hancock, Caroline Bateman, Sarah Inglott, Jon Mee, Javier Herrero, Peter Van Loo, Anthony V. Moorman, Ajay Vora, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1720–1721.
https://doi.org/10.1182/blood-2022-165308
Published: 2022
Journal Articles

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

Ana Rio-Machin, Findlay Bewicke-Copley, Jiexin Zheng, Pedro Casado Izquierdo, Juho J. Miettinen, Naeem Khan, Jonas Demeulemeester, Szilvia Krizsán, Christopher Middleton, Sam Benkwitz-Bedford, Joseph Saad, Amaia Vilas-Zornoza, Teresa Ezponda, William Grey, Vincent-Philippe Lavallée, Alexis Nolin-Lapalme, Farideh Miraki-Moud, Janet Matthews, Marianne Grantham, Ryan J Colm, Jonathan Bond, Doriana Di Bella, Krister Wennerberg, Alun Parsons, Andy G.X. Zeng, Hannah Armes, Karina Close, Fadimana Kaya, Kevin Rouault-Pierre, John G. Gribben, Felipe Prosper, James Cavenagh, John E. Dick, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, Guy Sauvageau, Kimmo Porkka, Caroline A. Heckman, Jun Wang, Jean-Baptiste Cazier, David Taussig, Dominique Bonnet, Pedro Cutillas, Jude Fitzgibbon
Journal: Blood
Blood (2022) 140 (Supplement 1): 1030–1032.
https://doi.org/10.1182/blood-2022-159069
Published: 2022
Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Ana Rio-Machin, Pedro Casado-Izquierdo, Juho Miettinen, PhD, Findlay Bewicke-Copley, PhD MSc, BSc, Naeem Khan, PhD, Jonas Demeulemeester, Szilvia Krizsán, MD, Jiexin Zheng, Christopher Middleton, Wencheng Yin, William Grey, Farideh Miraki-Moud, PhD, Janet Matthews, Marianne Grantham, Kevin Rouault-Pierre, PhD, Krister Wennerberg, Alun Parsons, Hannah Armes, Karina EM Close, Doriana Di Bella, James Cavenagh, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, PhD, Kimmo Porkka, Caroline A Heckman, PhD, Jun Wang, PhD, David Taussig, Dominique Bonnet, PhD, Jean-Baptiste Cazier, PhD, Pedro Cutillas, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-141345
Published: 2020
Journal Articles

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser, Jan De Rijck
Journal: Blood
Blood (2018) 131 (1): 95–107.
https://doi.org/10.1182/blood-2017-05-786962
Published: 2018
Includes: Supplemental data