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Journal Articles

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation

Blood blood.2024024505.

https://doi.org/10.1182/blood.2024024505

Published: 2024

Includes: Supplemental data

Journal Articles

Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid Leukemia

Federica Valigi, Fulya Mina Kücüktas, Ilya Fliamer, Zivojin Jevtic, Hughes-Etienne Chatel-Soulet, Amandine Bovay, Rathick Sivalingam, Andreja Baosic, Florian Grebien, Robert K. Slany, Alexandar Tzankov, Sabine Juge, Jonathan Seguin, Menghan Wang, Athimed El Taher, Luca Giorgetti, Juerg Schwaller

Blood (2024) 144 (Supplement 1): 2729.

https://doi.org/10.1182/blood-2024-207011

Published: 2024

Journal Articles

MLL-AF9-Induced Leukaemia Changes during Ontogenic Stages

Meaad Saeed Almowaled, Lijun Liu, Karen Dunn, Myint Myat Khine Aung, Gillian Horne, Juerg Schwaller, Karen Keeshan

Blood (2023) 142 (Supplement 1): 2761.

https://doi.org/10.1182/blood-2023-185911

Published: 2023

Journal Articles

The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam, Matheus Filgueira Bezerra, Amber Louwagie, Sabine Juge, Ioannis Nellas, Robert Ivanek, Alexandar Tzankov, Ute M. Moll, Oriano Cantillo, Ramona Schulz-Heddergott, Alexandre Fagnan, Thomas Mercher, Juerg Schwaller

Blood (2023) 141 (18): 2245–2260.

https://doi.org/10.1182/blood.2022017273

Published: 2023

Includes: Supplemental data

Journal Articles

High-mobility-group protein A1 in MPN progression

Juerg Schwaller

Blood (2022) 139 (18): 2730–2732.

https://doi.org/10.1182/blood.2022016145

Published: 2022

Journal Articles

MLL-AF4 + infant leukemia: a microRNA affair

Juerg Schwaller

Blood (2021) 138 (21): 2014–2015.

https://doi.org/10.1182/blood.2021012818

Published: 2021

Journal Articles

Modeling the Cellular Origin of EVI1 + MLL-AF9-Driven Acute Myeloid Leukemia (AML)

Hugues-Etienne Chatel-Soulet, Sabine Juge, Frederik Otzen Bagger, Alexandar Tzankov, Mineo Kurokawa, Jonathan Séguin, Juerg Schwaller

Blood (2021) 138 (Supplement 1): 2210.

https://doi.org/10.1182/blood-2021-149439

Published: 2021

Journal Articles

Dissecting GATA1 Protein Interactions in Normal and Malignant Human Erythroblasts

Samantha Tauchmann, Frederik Otzen Bagger, Thomas Bock, Roos Krimpenfort, Francesca Aglialoro, Peter Valent, Alexandre Fagnan, Marieke von Lindern, Thomas Mercher, Juerg Schwaller

Blood (2021) 138 (Supplement 1): 3293.

https://doi.org/10.1182/blood-2021-148351

Published: 2021

Journal Articles

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Blood (2020) 136 (6): 698–714.

https://doi.org/10.1182/blood.2019003062

Published: 2020

Includes: Supplemental data

Journal Articles

Transformation Mechanisms of the Nfia -ETO2 Fusion Gene Associated with Pediatric Pure Acute Erythroleukemia

Maria-Riera Piqué-Borràs, Msc, Frederik Otzen Bagger, PhD, Matheus Filgueira Bezerra, MSc, Amber Louwaige, Msc, Sabine Juge, Ioannis Nellas, Msc, Robert Ivanek, PhD, Alexandar Tzankov, MD, Ute M Moll, MD, Ramona Schulz-Heddergott, PhD, Thomas Mercher, PhD, Juerg Schwaller, MD

Blood (2019) 134 (Supplement_1): 532.

https://doi.org/10.1182/blood-2019-126416

Published: 2019

Journal Articles

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser, Jan De Rijck

Blood (2018) 131 (1): 95–107.

https://doi.org/10.1182/blood-2017-05-786962

Published: 2018

Includes: Supplemental data

Journal Articles

Leukemic Stem Cells Co-Opt Normal Bone Marrow Niches As a Source of Energy and Antioxidant Defence

Dorian Forte, PhD, María García-Fernández, Abel Sánchez-Aguilera, Vaya Stavropoulou, Claire Fielding, Daniel Martín-Pérez, Alexandar Tzankov, Juerg Schwaller, MD, Simón Méndez-Ferrer

Blood (2017) 130 (Supplement 1): 94.

https://doi.org/10.1182/blood.V130.Suppl_1.94.94

Published: 2017

Journal Articles

Fetal Inactivation of the Nuclear Interacting SET Domain Protein 1 Impairs Terminal Erythroid Maturation and Results in Acute Erythroleukemia in Mice

Katharina Leonards, PhD, Marwa Almosailleakh, MSc, Samantha Tauchmann, Msc, Helene Mereau, PhD, Sabine Juge, Matheus Filgueira Bezerra, MSc, Susanne Kasper, PhD, Robert Ivanek, PhD, Alexandar Tzankov, Antoine HFM Peters, PhD, Juerg Schwaller, MD

Blood (2017) 130 (Supplement 1): 713.

https://doi.org/10.1182/blood.V130.Suppl_1.713.713

Published: 2017

Journal Articles

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Jarno Kivioja, MSc, Angeliki Thanasopoulou, PhD, Mika Kontro, MD, Bhagwan Yadav, MSc, Muntasir Mamun Majumder, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Kimmo Porkka, MD PhD, Juerg Schwaller, MD, Caroline A Heckman, PhD

Blood (2016) 128 (22): 4711.

https://doi.org/10.1182/blood.V128.22.4711.4711

Published: 2016

Journal Articles

ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia

Blood (2016) 128 (22): 572.

https://doi.org/10.1182/blood.V128.22.572.572

Published: 2016

Journal Articles

Conditional Expression of a Leukemogenic Fusion Oncogene in Murine Hematopoietic Stem Cells Results in Highly Invasive AML with Origin-Related Genetic Signatures of Prognostic Significance for the Human Disease

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Alexander Tzankov, MD PhD, Mathijs A. Sanders, MSc, Michael Kyba, PhD, Peter J.M. Valk, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD

Blood (2014) 124 (21): 779.

https://doi.org/10.1182/blood.V124.21.779.779

Published: 2014

Journal Articles

Targeting Aberrant Self-Renewal of Leukemic Cells with a Novel CBP/p300 Bromodomain Inhibitor

Angeliki Thanasopoulou, PhD, Katharina Dumrese, Sarah Picaud, PhD, Oleg Fedorov, PhD, Stefan Knapp, PhD, Juerg Schwaller, MD

Blood (2014) 124 (21): 3750.

https://doi.org/10.1182/blood.V124.21.3750.3750

Published: 2014

Journal Articles

Identification of Novel Therapeutic Strategies for NUP98-NSD1-Positive AML By Drug Sensitivity Profiling

Jarno Kivioja, MSc, Mika Kontro, MD, Angeliki Thanasopoulou, PhD, Muntasir Mamun Majumder, MSc,BPharm, Bhagwan Yadav, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Juerg Schwaller, MD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD

Blood (2014) 124 (21): 2160.

https://doi.org/10.1182/blood.V124.21.2160.2160

Published: 2014

Journal Articles

Potent Cooperation Between NUP98-NSD1 and FLT3-ITD In AML Induction

Angeliki Thanasopoulou, PhD, Alexandar Tzankov, M.D., Juerg Schwaller, MD

Blood (2013) 122 (21): 3797.

https://doi.org/10.1182/blood.V122.21.3797.3797

Published: 2013

Journal Articles

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Vaia Stavropoulou, PhD, Sabine Juge, Alexander Tzankov, MD, PhD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD

Blood (2013) 122 (21): 1277.

https://doi.org/10.1182/blood.V122.21.1277.1277

Published: 2013

NARROW

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation

Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid Leukemia

MLL-AF9-Induced Leukaemia Changes during Ontogenic Stages

The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

High-mobility-group protein A1 in MPN progression

MLL-AF4 + infant leukemia: a microRNA affair

Modeling the Cellular Origin of EVI1 + MLL-AF9-Driven Acute Myeloid Leukemia (AML)

Dissecting GATA1 Protein Interactions in Normal and Malignant Human Erythroblasts

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Transformation Mechanisms of the Nfia -ETO2 Fusion Gene Associated with Pediatric Pure Acute Erythroleukemia

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

Leukemic Stem Cells Co-Opt Normal Bone Marrow Niches As a Source of Energy and Antioxidant Defence

Fetal Inactivation of the Nuclear Interacting SET Domain Protein 1 Impairs Terminal Erythroid Maturation and Results in Acute Erythroleukemia in Mice

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia

Conditional Expression of a Leukemogenic Fusion Oncogene in Murine Hematopoietic Stem Cells Results in Highly Invasive AML with Origin-Related Genetic Signatures of Prognostic Significance for the Human Disease

Targeting Aberrant Self-Renewal of Leukemic Cells with a Novel CBP/p300 Bromodomain Inhibitor

Identification of Novel Therapeutic Strategies for NUP98-NSD1-Positive AML By Drug Sensitivity Profiling

Potent Cooperation Between NUP98-NSD1 and FLT3-ITD In AML Induction

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

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American Society of Hematology

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American Society of Hematology

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