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Florian Grebien
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Journal Articles

Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid Leukemia

Federica Valigi, Fulya Mina Kücüktas, Ilya Fliamer, Zivojin Jevtic, Hughes-Etienne Chatel-Soulet, Amandine Bovay, Rathick Sivalingam, Andreja Baosic, Florian Grebien, Robert K. Slany, Alexandar Tzankov, Sabine Juge, Jonathan Seguin, Menghan Wang, Athimed El Taher, Luca Giorgetti, Juerg Schwaller
Journal: Blood
Blood (2024) 144 (Supplement 1): 2729.
https://doi.org/10.1182/blood-2024-207011
Published: 2024
Journal Articles

Impact of Mono- and Bi-Allelic TP53 Aberrations on Transformation of Human HSPCs

Karin Lind, Sayantanee Dutta, Marco Cosenza, Thomas Eder, Johannes Foßelteder, Gabriel Pabst, Wolfgang Schöll, Andreas Prokesch, Andreas Reinisch, Albert Woelfler, Armin Zebisch, Florian Grebien, Jan O. Korbel, Heinz Sill
Journal: Blood
Blood (2024) 144 (Supplement 1): 5631.
https://doi.org/10.1182/blood-2024-203217
Published: 2024
Journal Articles

Ly6C + Inflammatory Monocytes Create a Leukemia-Initiating Niche

Lukas Kazianka, Michaela Prchal-Murphy, Christiane Agreiter, Carmen Schweicker, Maurizio Forte, Emiel van der Kouwe, Christoph Kornauth, Alexander Pichler, Tea Pemovska, Johannes Rohrbeck, Margit Schmeidl, Selina Troester, Julia List, Veronika Sexl, Florian Grebien, Peter Valent, Daniel G. Tenen, Philipp Bernhard Staber
Journal: Blood
Blood (2024) 144 (Supplement 1): 881.
https://doi.org/10.1182/blood-2024-208750
Published: 2024
Journal Articles

SBNO2 is a critical mediator of STAT3-driven hematological malignancies

Tania Brandstoetter, Johannes Schmoellerl, Reinhard Grausenburger, Sebastian Kollmann, Eszter Doma, Jani Huuhtanen, Thorsten Klampfl, Thomas Eder, Florian Grebien, Gregor Hoermann, Johannes Zuber, Satu Mustjoki, Barbara Maurer, Veronika Sexl
Journal: Blood
Blood (2023) 141 (15): 1831–1845.
https://doi.org/10.1182/blood.2022018494
Published: 2023
Includes: Supplemental data
Journal Articles

EVI1 drives leukemogenesis through aberrant ERG activation

Johannes Schmoellerl, Inês A.M. Barbosa, Martina Minnich, Florian Andersch, Leonie Smeenk, Marije Havermans, Thomas Eder, Tobias Neumann, Julian Jude, Michaela Fellner, Anja Ebert, Monika Steininger, Ruud Delwel, Florian Grebien, Johannes Zuber
Journal: Blood
Blood (2023) 141 (5): 453–466.
https://doi.org/10.1182/blood.2022016592
Published: 2023
Includes: Supplemental data
Journal Articles

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Johannes Schmoellerl, Inês Amorim Monteiro Barbosa, Thomas Eder, Tania Brandstoetter, Luisa Schmidt, Barbara Maurer, Selina Troester, Ha Thi Thanh Pham, Mohanty Sagarajit, Jessica Ebner, Gabriele Manhart, Ezgi Aslan, Stefan Terlecki-Zaniewicz, Christa Van der Veen, Gregor Hoermann, Nicolas Duployez, Arnaud Petit, Helene Lapillonne, Alexandre Puissant, Raphael Itzykson, Richard Moriggl, Michael Heuser, Roland Meisel, Peter Valent, Veronika Sexl, Johannes Zuber, Florian Grebien
Journal: Blood
Blood (2020) 136 (4): 387–400.
https://doi.org/10.1182/blood.2019003267
Published: 2020
Includes: Supplemental data
Journal Articles

Further Evaluation of Pro-Atherogenic and Anti-Angiogenic Effects of Nilotinib in Mice and in Patients with Ph-Chromosome+ CML

Emir Hadzijusufovic, DVM, Karin Albrecht-Schgoer, PhD, Kilian Huber, PhD, Florian Grebien, PhD, Gregor Eisenwort, MD PhD, Wilfried Schgoer, MD PhD, Christoph Kaun, Susanne Herndlhofer, Markus Theurl, PhD, Sabine Cerny-Reiterer, DVM, Gregor Hoermann, MD PhD, Wolfgang R Sperr, MD, Uwe Rix, PhD, Irina Sadovnik, MSc, Bernd Jilma, MD, Gerit Holger Schernthaner, MD, Johann Wojta, PhD, Dominik Wolf, MD, Giulio Superti-Furga, PhD, Rudolf Kirchmair, MD, Peter Valent, MD
Journal: Blood
Blood (2014) 124 (21): 1800.
https://doi.org/10.1182/blood.V124.21.1800.1800
Published: 2014
Journal Articles

Nilotinib Exerts Direct Pro-Atherogenic and Anti-Angiogenic Effects On Vascular Endothelial Cells: A Potential Explanation For Drug-Induced Vasculopathy In CML

Hadzijusufovic Emir, DVM, Karin Albrecht-Schgoer, PhD, Kilian Huber, PhD, Florian Grebien, PhD, Gregor Eisenwort, MD, PhD, Wilfried Schgoer, MD, PhD, Christoph Kaun, Susanne Herndlhofer, Markus Theurl, PhD, Sabine Cerny-Reiterer, D.V.M., Gregor Hoermann, M.D., Ph.D., Wolfgang R Sperr, M.D., Rix Uwe, PhD, Johann Wojta, PhD, Dominik Wolf, MD, Giulio Superti-Furga, PhD, Rudolf Kirchmair, MD, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 257.
https://doi.org/10.1182/blood.V122.21.257.257
Published: 2013
Journal Articles

In Vivo Screening for Tumor Suppressors In Hematological Malignancies Using Barcode RNAi

Roland Jäger, Markus Muellner, Florian Grebien, Thorsten Klampfl, Ashot Harutyunyan, Damla Olcaydu, Tiina Berg, Sebastian Nijman, Robert Kralovics
Journal: Blood
Blood (2010) 116 (21): 998.
https://doi.org/10.1182/blood.V116.21.998.998
Published: 2010
Journal Articles

Bcr-Abl Directly Activates Stat5 Independent of Jak2

Oliver D. Hantschel, MSc, PhD, Eva Eckelhart, MSc, Ines Kaupe, MSc, Florian Grebien, MSc, PhD, Kay-Uwe Wagner, PhD, Veronika Sexl, MD, Giulio Superti-Furga, PhD
Journal: Blood
Blood (2010) 116 (21): 511.
https://doi.org/10.1182/blood.V116.21.511.511
Published: 2010
Journal Articles

Functional Genomic and Proteomic Characterization of Normal and Oncogenic CEBPA Variants In Myeloid Cells

Florian Grebien, Roberto Giambruno, Keiryn L Bennett, Jacques Colinge, Giulio Superti-Furga
Journal: Blood
Blood (2010) 116 (21): 3873.
https://doi.org/10.1182/blood.V116.21.3873.3873
Published: 2010
Journal Articles

The Bcr-Abl SH2-Kinase Domain Interface Is Critical for Leukemogenesis and An Additional Therapeutic Target in CML.

Oliver D. Hantschel, PhD, Florian Grebien, Ines Kaupe, Boris Kovacic, John Wojcik, Gerald D Gish, Shohei Koide, Hartmut Beug, Tony Pawson, Giulio Superti-Furga
Journal: Blood
Blood (2009) 114 (22): 37.
https://doi.org/10.1182/blood.V114.22.37.37
Published: 2009
Journal Articles

Structural Positioning of the SH2 Domain Is Critical for Bcr-Abl Kinase Activity, Signal Transduction and Oncogenic Transformation

Oliver D. Hantschel, PhD, Florian Grebien, Ines Kaupe, Giulio Superti-Furga
Journal: Blood
Blood (2008) 112 (11): 569.
https://doi.org/10.1182/blood.V112.11.569.569
Published: 2008
Journal Articles

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1

Marc A. Kerenyi, Florian Grebien, Helmuth Gehart, Manfred Schifrer, Matthias Artaker, Boris Kovacic, Hartmut Beug, Richard Moriggl, Ernst W. Müllner
Journal: Blood
Blood (2008) 112 (9): 3878–3888.
https://doi.org/10.1182/blood-2008-02-138339
Published: 2008
Includes: Supplemental data
Journal Articles

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2

Florian Grebien, Marc A. Kerenyi, Boris Kovacic, Thomas Kolbe, Verena Becker, Helmut Dolznig, Klaus Pfeffer, Ursula Klingmüller, Mathias Müller, Hartmut Beug, Ernst W. Müllner, Richard Moriggl
Journal: Blood
Blood (2008) 111 (9): 4511–4522.
https://doi.org/10.1182/blood-2007-07-102848
Published: 2008
Includes: Supplemental data