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Journal Articles

Determining the origin of TP53 mutations in patients with mature B-cell neoplasms is essential to distinguish lymphoma-related mutations from those due to clonal hematopoiesis, helping to guide treatment decisions

Veronika Ecker, Wencke Walter, Martha-Lena Mueller, Nicola Goetz, Christiane Eder, Manja Meggendorfer, Sandra Huber, Jana Wobst, Wolfgang Kern, Gregor Hoermann

Blood (2025) 146 (Supplement 1): 5389.

https://doi.org/10.1182/blood-2025-5389

Published: 2025

Journal Articles

Multiple myeloma with concomitant chronic lymphocytic leukemia: Common or distinct clonal origin?

Jana Wobst, Henning Ruge, Sara Senk, Marietta Truger, Alessandro Baldi, Gregor Hoermann, Torsten Haferlach

Blood (2025) 146 (Supplement 1): 3981.

https://doi.org/10.1182/blood-2025-3981

Published: 2025

Journal Articles

Long-term event-free survival in patients with IGHV-mutated high-count monoclonal B-cell lymphocytosis and atypical, non-CLL-like phenotypes

Jan-Paul Bohn, Stephanie Grabenwarter, Leilu Mangold, Martyna Bartkowiak, Katrin Schweneker, Gregor Hoermann, Normann Steiner, Manuela Hoechstetter, Torsten Haferlach, Clemens-Martin Wendtner, Dominik Wolf

Blood (2025) 146 (Supplement 1): 2112.

https://doi.org/10.1182/blood-2025-2112

Published: 2025

Journal Articles

Additional genetic targets are present in the majority of AML patients with NPM1, KMT2A or NUP98 aberrations potentially impacting combination therapy with menin inhibitors

Rainer Ordemann, Sandra Huber, Alessandro Baldi, Anna Stengel, Irene Fuhrmann, Christian Pohlkamp, Manja Meggendorfer, Sabit Delic, Wolfgang Kern, Torsten Haferlach, Gregor Hoermann

Blood (2025) 146 (Supplement 1): 5248.

https://doi.org/10.1182/blood-2025-5248

Published: 2025

Journal Articles

Two Ways to Complex Karyotype in MDS - the Role of Del(5q) and TP53

Claudia Haferlach, Sandra Huber, Stephan Hutter, Constance Regina Baer, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach

Blood (2024) 144 (Supplement 1): 1836.

https://doi.org/10.1182/blood-2024-201270

Published: 2024

Journal Articles

Similarities and Differences of DNMT3A , TET2 and ASXL1 Mutations across Ccus, MDS and AML

Sandra Huber, Stephan Hutter, Constance Regina Baer, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2024) 144 (Supplement 1): 1819.

https://doi.org/10.1182/blood-2024-200561

Published: 2024

Journal Articles

Mutant Idh1 Blocks Neutrophil Maturation By Repressing Myeloid Progenitor Programs

Blood (2024) 144 (Supplement 1): 1341.

https://doi.org/10.1182/blood-2024-210352

Published: 2024

Journal Articles

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A. Betram, Richard Moriggl, Thomas Rülicke, Charles G. Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt

Blood (2024) 143 (24): 2474–2489.

https://doi.org/10.1182/blood.2023022655

Published: 2024

Includes: Supplemental data

Journal Articles

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Francis Baumgartner, Constance Baer, Stefanos Bamopoulos, Edward Ayoub, Marietta Truger, Manja Meggendorfer, Miriam Lenk, Gregor Hoermann, Stephan Hutter, Heiko Müller, Wencke Walter, Martha-Lena Müller, Niroshan Nadarajah, Piers Blombery, Ulrich Keller, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

Blood (2024) 143 (12): 1139–1156.

https://doi.org/10.1182/blood.2023021199

Published: 2024

Includes: Supplemental data

Journal Articles

Tumor necrosis factor α promotes clonal dominance of KIT D816V + cells in mastocytosis: role of survivin and impact on prognosis

Blood (2024) 143 (11): 1006–1017.

https://doi.org/10.1182/blood.2023020515

Published: 2024

Includes: Supplemental data

Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour

Blood (2023) 142 (25): 2175–2191.

https://doi.org/10.1182/blood.2022015752

Published: 2023

Includes: Supplemental data

Journal Articles

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

Constance Regina Baer, Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 725.

https://doi.org/10.1182/blood-2023-179737

Published: 2023

Journal Articles

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Constance Regina Baer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 3184.

https://doi.org/10.1182/blood-2023-174872

Published: 2023

Journal Articles

Modification of the ELN Classification 2022 Refines Risk Assessment in MDS/AML Patients

Sandra Huber, Constance Regina Baer, Stephan Hutter, Frank Dicker, Irene Fuhrmann, Manja Meggendorfer, Christian Pohlkamp, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Gregor Hoermann

Blood (2023) 142 (Supplement 1): 61.

https://doi.org/10.1182/blood-2023-179822

Published: 2023

Journal Articles

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Claudia Haferlach, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Gregor Hoermann, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 6492.

https://doi.org/10.1182/blood-2023-179188

Published: 2023

Journal Articles

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Claudia Haferlach, Wencke Walter, Heiko Mueller, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 3170.

https://doi.org/10.1182/blood-2023-185867

Published: 2023

Journal Articles

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Sandra Huber, Constance Regina Baer, Stephan Hutter, Gregor Hoermann, Christian Pohlkamp, Wencke Walter, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 4609.

https://doi.org/10.1182/blood-2023-177582

Published: 2023

Journal Articles

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

Sandra Huber, Natalie Wossidlo, Torsten Haferlach, Manja Meggendorfer, Stephan Hutter, Gregor Hoermann, Isolde Summerer, Henning Ruge, Constance Regina Baer, Wolfgang Kern, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 198.

https://doi.org/10.1182/blood-2023-174843

Published: 2023

Journal Articles

SBNO2 is a critical mediator of STAT3-driven hematological malignancies

Tania Brandstoetter, Johannes Schmoellerl, Reinhard Grausenburger, Sebastian Kollmann, Eszter Doma, Jani Huuhtanen, Thorsten Klampfl, Thomas Eder, Florian Grebien, Gregor Hoermann, Johannes Zuber, Satu Mustjoki, Barbara Maurer, Veronika Sexl

Blood (2023) 141 (15): 1831–1845.

https://doi.org/10.1182/blood.2022018494

Published: 2023

Includes: Supplemental data

Journal Articles

Delineation of Predictive Features of AML Patients with Recurrent Relapse Who Achieved Repeated Complete Remission after Multiple Re-Induction and Consolidation Therapies

Irene Graf, Georg Greiner, Karoline V. Gleixner, Susanne Herndlhofer, Gabriele Stefanzl, Paul Knöbl, Alexander Hauswirth, Manja Meggendorfer, Ulrich Jaeger, Constance Baer, Torsten Haferlach, Gregor Hoermann, Peter Valent, Wolfgang R. Sperr

Blood (2022) 140 (Supplement 1): 11634–11635.

https://doi.org/10.1182/blood-2022-162588

Published: 2022

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Determining the origin of TP53 mutations in patients with mature B-cell neoplasms is essential to distinguish lymphoma-related mutations from those due to clonal hematopoiesis, helping to guide treatment decisions

Multiple myeloma with concomitant chronic lymphocytic leukemia: Common or distinct clonal origin?

Long-term event-free survival in patients with IGHV-mutated high-count monoclonal B-cell lymphocytosis and atypical, non-CLL-like phenotypes

Additional genetic targets are present in the majority of AML patients with NPM1, KMT2A or NUP98 aberrations potentially impacting combination therapy with menin inhibitors

Two Ways to Complex Karyotype in MDS - the Role of Del(5q) and TP53

Similarities and Differences of DNMT3A , TET2 and ASXL1 Mutations across Ccus, MDS and AML

Mutant Idh1 Blocks Neutrophil Maturation By Repressing Myeloid Progenitor Programs

A lineage-specific STAT5B N642H mouse model to study NK-cell leukemia

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Tumor necrosis factor α promotes clonal dominance of KIT D816V + cells in mastocytosis: role of survivin and impact on prognosis

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Modification of the ELN Classification 2022 Refines Risk Assessment in MDS/AML Patients

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

SBNO2 is a critical mediator of STAT3-driven hematological malignancies

Delineation of Predictive Features of AML Patients with Recurrent Relapse Who Achieved Repeated Complete Remission after Multiple Re-Induction and Consolidation Therapies

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