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Journal Articles

Clonal Hematopoiesis Can Precede AML with Defining Cytogenetic Abnormalities - the Frequencies Vary Considerably

Anetta Marcinek, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Torsten Haferlach, Wolfgang Kern, Claudia Haferlach

Blood (2024) 144 (Supplement 1): 4318.

https://doi.org/10.1182/blood-2024-204966

Published: 2024

Journal Articles

Integrateall, a Machine Learning Pipeline for Multi-Level Data Extraction from RNA-Seq Profiles Unravels Novel Drivers and Systematic Subtype Classification in B-Cell Precursor ALL

Nadine Wolgast, Thomas Beder, Mayukh Mondal, Wencke Walter, Stephan Hutter, Sonja Bendig, Jan Kässens, Björn-Thore Hansen, Katharina Iben, Barz Malwine, Martin Neumann, Nicola Goekbuget, Claudia Haferlach, Monika Brüggemann, Claudia D Baldus, Alina M. Hartmann, Lorenz Bastian

Blood (2024) 144 (Supplement 1): 4213.

https://doi.org/10.1182/blood-2024-199557

Published: 2024

Journal Articles

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

Carlos Bravo-Perez, Carmelo Gurnari, Arda Durmaz, Stephan Hutter, Zachary Brady, Hussein Awada, Aashray Mandala, Luca Guarnera, Matteo D'Addona, Kartik Lakhotiya, Praveena Thiagarajan, Alan Eli Lichtin, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 31.

https://doi.org/10.1182/blood-2024-208885

Published: 2024

Journal Articles

A Unified Post-Transcriptional Mechanism Regulates Intron Retention in Splicing Factor-Mutant MDS

Prajwal Boddu, Rahul Roy, Francis Baumgartner, Stephan Hutter, Torsten Haferlach, Manoj Pillai

Blood (2024) 144 (Supplement 1): 2732.

https://doi.org/10.1182/blood-2024-211458

Published: 2024

Journal Articles

Similarities and Differences of DNMT3A , TET2 and ASXL1 Mutations across Ccus, MDS and AML

Sandra Huber, Stephan Hutter, Constance Regina Baer, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2024) 144 (Supplement 1): 1819.

https://doi.org/10.1182/blood-2024-200561

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

Secondary Cytogenetic and Molecular Genetic Abnormalities in Newly Diagnosed Multiple Myeloma Patients

Jana Wobst, Marietta Truger, Natalie Wossidlo, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2024) 144 (Supplement 1): 899.

https://doi.org/10.1182/blood-2024-204832

Published: 2024

Journal Articles

Two Ways to Complex Karyotype in MDS - the Role of Del(5q) and TP53

Claudia Haferlach, Sandra Huber, Stephan Hutter, Constance Regina Baer, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach

Blood (2024) 144 (Supplement 1): 1836.

https://doi.org/10.1182/blood-2024-201270

Published: 2024

Journal Articles

Phenotypic and Genetic Heterogeneity of NPM1 Mutated AML at Diagnosis and during Course of Disease

Veronika Ecker, Sandra Huber, Wencke Walter, Stephan Hutter, Martha-Lena Mueller, Manja Meggendorfer, Constance Regina Baer, Claudia Haferlach, Torsten Haferlach, Wolfgang Kern

Blood (2024) 144 (Supplement 1): 6118.

https://doi.org/10.1182/blood-2024-209675

Published: 2024

Journal Articles

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Francis Baumgartner, Constance Baer, Stefanos Bamopoulos, Edward Ayoub, Marietta Truger, Manja Meggendorfer, Miriam Lenk, Gregor Hoermann, Stephan Hutter, Heiko Müller, Wencke Walter, Martha-Lena Müller, Niroshan Nadarajah, Piers Blombery, Ulrich Keller, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

Blood (2024) 143 (12): 1139–1156.

https://doi.org/10.1182/blood.2023021199

Published: 2024

Includes: Supplemental data

Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour

Blood (2023) 142 (25): 2175–2191.

https://doi.org/10.1182/blood.2022015752

Published: 2023

Includes: Supplemental data

Journal Articles

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Constance Regina Baer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 3184.

https://doi.org/10.1182/blood-2023-174872

Published: 2023

Journal Articles

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

Sandra Huber, Natalie Wossidlo, Torsten Haferlach, Manja Meggendorfer, Stephan Hutter, Gregor Hoermann, Isolde Summerer, Henning Ruge, Constance Regina Baer, Wolfgang Kern, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 198.

https://doi.org/10.1182/blood-2023-174843

Published: 2023

Journal Articles

Can Whole Genome and Whole Transcriptome Sequencing Replace Standard Procedures in CLL Diagnostics?

Heiko Mueller, Wencke Walter, Manja Meggendorfer, Stephan Hutter, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 1912.

https://doi.org/10.1182/blood-2023-185732

Published: 2023

Journal Articles

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Sandra Huber, Constance Regina Baer, Stephan Hutter, Gregor Hoermann, Christian Pohlkamp, Wencke Walter, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 4609.

https://doi.org/10.1182/blood-2023-177582

Published: 2023

Journal Articles

Characterization of Cases with the Rare Cytogenetic Abnormality I(7)(p10) Reveals an Association with IDH2 Mutated Acute Myeloid Leukemia

Anna Stengel, Manja Meggendorfer, Constance Regina Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 5987.

https://doi.org/10.1182/blood-2023-179844

Published: 2023

Journal Articles

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

Constance Regina Baer, Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 725.

https://doi.org/10.1182/blood-2023-179737

Published: 2023

Journal Articles

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Claudia Haferlach, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Gregor Hoermann, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 6492.

https://doi.org/10.1182/blood-2023-179188

Published: 2023

Journal Articles

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Claudia Haferlach, Wencke Walter, Heiko Mueller, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 3170.

https://doi.org/10.1182/blood-2023-185867

Published: 2023

Journal Articles

Proposal ofmyeloid Neoplasms with MYC -Positive Double Minutes As a Distinct Entity

Isolde Summerer, Wencke Walter, Manja Meggendorfer, Torsten Haferlach, Frank Dicker, Stephan Hutter, Niroshan Nadarajah, Constance Regina Baer, Anna Stengel, Wolfgang Kern, John M. Bennett, Claudia Haferlach, Christian Pohlkamp

Blood (2023) 142 (Supplement 1): 2930.

https://doi.org/10.1182/blood-2023-189902

Published: 2023

NARROW

Clonal Hematopoiesis Can Precede AML with Defining Cytogenetic Abnormalities - the Frequencies Vary Considerably

Integrateall, a Machine Learning Pipeline for Multi-Level Data Extraction from RNA-Seq Profiles Unravels Novel Drivers and Systematic Subtype Classification in B-Cell Precursor ALL

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

A Unified Post-Transcriptional Mechanism Regulates Intron Retention in Splicing Factor-Mutant MDS

Similarities and Differences of DNMT3A , TET2 and ASXL1 Mutations across Ccus, MDS and AML

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Secondary Cytogenetic and Molecular Genetic Abnormalities in Newly Diagnosed Multiple Myeloma Patients

Two Ways to Complex Karyotype in MDS - the Role of Del(5q) and TP53

Phenotypic and Genetic Heterogeneity of NPM1 Mutated AML at Diagnosis and during Course of Disease

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

Can Whole Genome and Whole Transcriptome Sequencing Replace Standard Procedures in CLL Diagnostics?

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Characterization of Cases with the Rare Cytogenetic Abnormality I(7)(p10) Reveals an Association with IDH2 Mutated Acute Myeloid Leukemia

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Proposal ofmyeloid Neoplasms with MYC -Positive Double Minutes As a Distinct Entity

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American Society of Hematology

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American Society of Hematology

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