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Naomi Kawashima
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Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Luca Guarnera, Adam Wahida, Carmelo Gurnari, Stephan Hutter, Sabine Stainczyk, Nakisha D Williams, Arda Durmaz, Yasuo Kubota, Carlos Bravo-Perez, Naomi Kawashima, Simona Pagliuca, Yimin Huang, Thomas Laframboise, Valeria Visconte, Wencke Walter, Manja Meggendorfer, Claudia Haferlach, Wolfgang Kern, Frank Westermann, Lars Feuerbach, Torsten Haferlach, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4104.
https://doi.org/10.1182/blood-2024-209923
Published: 2024
Journal Articles

Analysis of On-Target and Off-Target Resistance Factors Associated with Gilteritinib Efficacy in Relapsed or Refractory AML Patients with FLT3 Mutations

Satoshi Iwata, Yuichi Ishikawa, Yoko Ushijima, Kotaro Miyao, Yasuhiko Harada, Takahiro Nishiyama, Naoko Hosono, Koichi Watamoto, Emiko Sakaida, Keiko Niimi, Miki Kobayashi, Kazutaka Ozeki, Tetsuya Nishida, Shingo Kurahashi, Yukiyasu Ozawa, Jeong Hui Kim, Seara Naruse, Marie Nakashima, Naomi Kawashima, Yachiyo Kuwatsuka, Hitoshi Kiyoi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6090.
https://doi.org/10.1182/blood-2024-199957
Published: 2024
Journal Articles

Distinct Phenotypes of Myeloid Neoplasia Associated with Truncating C-CBL Mutations

Luca Guarnera, Carmelo Gurnari, Carlos Bravo-Perez, Arda Durmaz, Nakisha D Williams, Hussein Awada, Matteo D'Addona, Naomi Kawashima, Arooj Ahmed, Serhan Unlu, Olisaemeka Ogbue, Christopher Haddad, Aashray Mandala, Yasuo Kubota, Juraj Bodo, Genevieve M Crane, Heesun J. Rogers, Jaroslaw Maciejewski, Valeria Visconte
Journal: Blood
Blood (2024) 144 (Supplement 1): 2920.
https://doi.org/10.1182/blood-2024-209834
Published: 2024
Journal Articles

Low-Count T-/NK-Large Granular Lymphocytic Leukemia: A Nosologically Distinct Disease Subtype at the Crossroads between Lymphoproliferation, Autoimmunity and Immunodeficiency

Carlos Bravo-Perez, Carmelo Gurnari, Arooj Ahmed, Naomi Kawashima, Zachary Brady, Matteo D'Addona, Luca Guarnera, Aashray Mandala, Kartik Lakhotiya, Christopher Haddad, Serhan Unlu, Mark Orland, Praveena Thiagarajan, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski
Journal: Blood
Blood (2024) 144 (Supplement 1): 1688.
https://doi.org/10.1182/blood-2024-209437
Published: 2024
Journal Articles

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Clinical Trials & Observations
Carmelo Gurnari, Hussein Awada, Simona Pagliuca, Danai Dima, Fauzia Ullah, Naomi Kawashima, Yasuo Kubota, Ceylan Colak, Valeria Visconte, Bhumika J. Patel, Vikram Dhillon, Naimisha Marneni, Suresh Kumar Balasubramanian, Ashwin Kishtagari, Taha Bat, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2024) 144 (2): 145–155.
https://doi.org/10.1182/blood.2024023988
Published: 2024
Journal Articles

Bone Marrow Failure and Inborn Errors of Immunity: An Immunogenomic Crossroad

Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Naomi Kawashima, Serhan Unlu, Aashray Mandala, Nakisha D Williams, Arooj Ahmed, Yasuo Kubota, Arda Durmaz, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 707.
https://doi.org/10.1182/blood-2023-183000
Published: 2023
Journal Articles

Unveiling the Spectrum of Inborn Errors of Immunity: Lessons from T-Cell LGL Clonal Expansions

Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Naomi Kawashima, Serhan Unlu, Aashray Mandala, Mark Orland, Olisaemeka Ogbue, Nakisha D Williams, Arooj Ahmed, Yasuo Kubota, Arda Durmaz, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 154.
https://doi.org/10.1182/blood-2023-182344
Published: 2023
Journal Articles

Geno-Multiomics Strategy Informs Drug Response Profiles in High-Risk Myeloid Neoplasia

Arda Durmaz, Sean Yetter, Tariq Kewan, Waled Bahaj, Carlos Bravo-Perez, Luca Guarnera, Naomi Kawashima, Hussein Awada, Carmelo Gurnari, Yasuo Kubota, Jacob Scott, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood
Blood (2023) 142 (Supplement 1): 5016.
https://doi.org/10.1182/blood-2023-190059
Published: 2023
Journal Articles

Reverse Engineering of Antigenic Peptides in LGL to Decipher Disease Triggers

Arda Durmaz, Carmelo Gurnari, Simona Pagliuca, Colin Hercus, Carlos Bravo-Perez, Luca Guarnera, Nakisha D Williams, Danai Dima, Ishani Nautiyal, Yasuo Kubota, Naomi Kawashima, Jacob Scott, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 246.
https://doi.org/10.1182/blood-2023-190381
Published: 2023
Journal Articles

Loss of Function MBD4 Mutation Impairs DNA Repair in Association with TET2 in Acute Myeloid Leukemia

Naomi Kawashima, Dongxu Jiang, Daniel Vail, Divya Jyoti Singh, Xiaorong Gu, Simon Schlanger, Carmelo Gurnari, Yasuo Kubota, Brittany L Stewart, Valeria Visconte, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 1371.
https://doi.org/10.1182/blood-2023-182142
Published: 2023
Journal Articles

LGL in MGUS or MGUS in LGL? Lessons of Nature and Their Clinical Implications

Carlos Bravo-Perez, Carmelo Gurnari, Naomi Kawashima, Danai Dima, Olisaemeka Ogbue, Luca Guarnera, Yasuo Kubota, Nakisha D Williams, Arooj Ahmed, Fauzia Ullah, Arda Durmaz, Megan Nakashima, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4769.
https://doi.org/10.1182/blood-2023-181975
Published: 2023
Journal Articles

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Dongxu Jiang, Yihong Guan, Shinjini Ganguly, Aysegul Balyimez, Andrew Muskara, Divya Jyoti Singh, Simona Pagliuca, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Xiaorong Gu, Carmelo Gurnari, Jaroslaw P. Maciejewski, Omar Mian, Babal K. Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2023-186924
Published: 2023
Journal Articles

Association Vs Causation: Epidemiologic Clues As to the Autoimmune Pathogenesis of MDS

Nakisha D Williams, Arda Durmaz, Carlos Bravo-Perez, Yasuo Kubota, Megan Reynold, Michaela Witt, Luca Guarnera, Morgan Ferrel, Aashray Mandala, Naomi Kawashima, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4066.
https://doi.org/10.1182/blood-2023-181916
Published: 2023
Journal Articles

Differential Isoforms Signature of Splicing Factor Mutant Myeloid Neoplasia

Arda Durmaz, Carmelo Gurnari, Carlos Bravo-Perez, Luca Guarnera, Yasuo Kubota, Naomi Kawashima, Ishani Nautiyal, Sean Yetter, Nakisha D Williams, Serhan Unlu, Sindhusha Veeraballi, Arooj Ahmed, Chao-Yie Yang, John Barnard, Jacob Scott, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood
Blood (2023) 142 (Supplement 1): 5701.
https://doi.org/10.1182/blood-2023-184752
Published: 2023
Journal Articles

Maladaptive Somatic Rescue in FLT3 Mutations of Suspected Germline Nature

Arooj Ahmed, Luca Guarnera, Jaymeson Gordon, Carlos Bravo-Perez, Arda Durmaz, Yasuo Kubota, Naomi Kawashima, Mark Orland, Nakisha D Williams, Christopher Haddad, Serhan Unlu, Sean Yetter, Sindhusha Veeraballi, Aashray Mandala, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 5666.
https://doi.org/10.1182/blood-2023-190837
Published: 2023
Journal Articles

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Divya Jyoti Singh, Metis Hasipek, Dongxu Jiang, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Simon Schlanger, Xiaorong Gu, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah, Hetty E. Carraway, Babal Kant Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 1422.
https://doi.org/10.1182/blood-2023-189274
Published: 2023
Journal Articles

Compound Heterozygosity Involving Other Dead ( DDX ) and Deah ( DHX ) Box Helicases Explains Seemingly Monoallelic Somatic and Germline DDX41 Mutations

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Luca Guarnera, Ishani Nautiyal, Megan Reynold, Nakisha D Williams, Yasuo Kubota, Naomi Kawashima, Benjamin Kroger, Stephen S. Chung, David S. Bosler, Carmelo Gurnari, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 947.
https://doi.org/10.1182/blood-2023-187195
Published: 2023
Journal Articles

Molecular Landscape of c-CBL Mutation in Adults' Myeloid Malignancies

Luca Guarnera, Carmelo Gurnari, Carlos Bravo-Perez, Arda Durmaz, Nakisha D Williams, Hussein Awada, Naomi Kawashima, Arooj Ahmed, Serhan Unlu, Christopher Haddad, Aashray Mandala, Yasuo Kubota, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood
Blood (2023) 142 (Supplement 1): 4336.
https://doi.org/10.1182/blood-2023-184962
Published: 2023
Journal Articles

Biallelic Landscape of DNMT3A Mutant Myeloid Neoplasia

Naomi Kawashima, Yasuo Kubota, Carmelo Gurnari, Carlos Bravo-Perez, Luca Guarnera, Nakisha D Williams, Arda Durmaz, Megan Reynold, Arooj Ahmed, Jaroslaw P. Maciejewski, Valeria Visconte
Journal: Blood
Blood (2023) 142 (Supplement 1): 1469.
https://doi.org/10.1182/blood-2023-181793
Published: 2023
Journal Articles

Outcomes of Antithymocyte Globulin and Cyclosporine for Severe Aplastic Anemia

Fauzia Ullah, Danai Dima, Carmelo Gurnari, Arooj Ahmed, Olisaemeka Ogbue, Mark Orland, Naomi Kawashima, Carlos Bravo-Perez, Serhan Unlu, Luca Guarnera, Najiullah Omar, Valeria Visconte, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 142 (Supplement 1): 5648.
https://doi.org/10.1182/blood-2023-191264
Published: 2023