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Journal Articles

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Jill Durkin, Daniel Vail, Dongxu Jiang, Yahan Zhang, Simon Schlanger, Jaroslaw Maciejewski, Thomas Laframboise, Babal K. Jha

Blood (2024) 144 (Supplement 1): 5727.

https://doi.org/10.1182/blood-2024-207943

Published: 2024

Journal Articles

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Dongxu Jiang, Yahan Zhang, Xiaorong Gu, Daniel J Vail, Jill Durkin, Simon Schlanger, J. Joseph Melenhorst, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 40.

https://doi.org/10.1182/blood-2024-211171

Published: 2024

Journal Articles

Metabolic Reprogramming By IDH1 Neomorph Epigenetically Guides CAR T Cell Differentiation

Kunho Chung, Dongxu Jiang, Xiaorong Gu, Jie Xu, Céline Grégoire, Beatriz Coutinho De Oliveira, Babal Kant Jha, J. Joseph Melenhorst

Blood (2024) 144 (Supplement 1): 1035.

https://doi.org/10.1182/blood-2024-205836

Published: 2024

Journal Articles

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Dongxu Jiang, Daniel J Vail, Yahan Zhang, Raziullah Khan, Anand Tiwari, Simon Schlanger, Kunho Chung, Cassandra Gilmour, Xiaorong Gu, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2664.

https://doi.org/10.1182/blood-2024-211363

Published: 2024

Journal Articles

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Daniel J Vail, Dongxu Jiang, Kunho Chung, Yahan Zhang, Sophia Martinez, Luca Guarnera, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 1278.

https://doi.org/10.1182/blood-2024-211683

Published: 2024

Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2918.

https://doi.org/10.1182/blood-2024-207470

Published: 2024

Journal Articles

PTPN12 Is Targetable and Context-Specific TSG in -7/del7q Myeloid Neoplasia

Daniel J Vail, Jill Durkin, Dongxu Jiang, Thomas Laframboise, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2756.

https://doi.org/10.1182/blood-2024-208538

Published: 2024

Journal Articles

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Xiaorong Gu, Songa Bae, Yahan Zhang, Nakisha D Williams, Dongxu Jiang, Simon Schlanger, Valeria Visconte, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 4159.

https://doi.org/10.1182/blood-2024-208348

Published: 2024

Journal Articles

Loss of TET2 Creates a Distinct Immunopeptidome in Acute Myeloid Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Daniel Vail, Simon Schlanger, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 4154.

https://doi.org/10.1182/blood-2024-208025

Published: 2024

Journal Articles

Loss of Function MBD4 Mutation Impairs DNA Repair in Association with TET2 in Acute Myeloid Leukemia

Naomi Kawashima, Dongxu Jiang, Daniel Vail, Divya Jyoti Singh, Xiaorong Gu, Simon Schlanger, Carmelo Gurnari, Yasuo Kubota, Brittany L Stewart, Valeria Visconte, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2023) 142 (Supplement 1): 1371.

https://doi.org/10.1182/blood-2023-182142

Published: 2023

Journal Articles

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Dongxu Jiang, Yihong Guan, Shinjini Ganguly, Aysegul Balyimez, Andrew Muskara, Divya Jyoti Singh, Simona Pagliuca, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Xiaorong Gu, Carmelo Gurnari, Jaroslaw P. Maciejewski, Omar Mian, Babal K. Jha

Blood (2023) 142 (Supplement 1): 2766.

https://doi.org/10.1182/blood-2023-186924

Published: 2023

Journal Articles

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Xiaorong Gu, Dongxu Jiang, Simon Schlanger, Nakisha D Williams, Divya Jyoti Singh, Daniel Vail, Jill Durkin, Yahan Zhang, Valeria Visconte, Jaroslaw P. Maciejewski, Babal Kant Jha

Blood (2023) 142 (Supplement 1): 2747.

https://doi.org/10.1182/blood-2023-189228

Published: 2023

Journal Articles

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Divya Jyoti Singh, Metis Hasipek, Dongxu Jiang, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Simon Schlanger, Xiaorong Gu, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah, Hetty E. Carraway, Babal Kant Jha

Blood (2023) 142 (Supplement 1): 1422.

https://doi.org/10.1182/blood-2023-189274

Published: 2023

Journal Articles

Role of MBD4 Mutation in Neoplastic Evolution of Acute Myeloid Leukemia

Naomi Kawashima, Dongxu Jiang, Divya Jyoti Singh, Dale Grabowski, Carmelo Gurnari, Yasuo Kubota, Mai Aly, Valeria Visconte, Brittany L Griffin, Torsten Haferlach, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2022) 140 (Supplement 1): 8783–8784.

https://doi.org/10.1182/blood-2022-163694

Published: 2022

Journal Articles

Demonstration That Loss of TET2 Impairs DNA Mismatch Repair Resulting in Clonally Restricted Genomic Instability

Dongxu Jiang, Feng Pan, Yihong Guan, Xiaorong Gu, Naomi Kawashima, Divya Jyoti Singh, Danai Dima, Guangbo Qu, Edward F Greenberg, Valeria Visconte, Omar Mian, Mingjiang Xu, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2022) 140 (Supplement 1): 1989–1990.

https://doi.org/10.1182/blood-2022-169467

Published: 2022

Journal Articles

Heightened Endoplasmic-Reticulum Stress Is a Targetable Vulnerability of Malignant Plasma Cells in Multiple Myeloma

Danai Dima, Metis Hasipek, Divya Jyoti Singh, Dongxu Jiang, Anand D. Tiwari, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Jianjun Zhao, Kenneth H. Shain, Jack Khouri, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2022) 140 (Supplement 1): 7100–7101.

https://doi.org/10.1182/blood-2022-169516

Published: 2022

NARROW

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Metabolic Reprogramming By IDH1 Neomorph Epigenetically Guides CAR T Cell Differentiation

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

PTPN12 Is Targetable and Context-Specific TSG in -7/del7q Myeloid Neoplasia

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Loss of TET2 Creates a Distinct Immunopeptidome in Acute Myeloid Leukemia

Loss of Function MBD4 Mutation Impairs DNA Repair in Association with TET2 in Acute Myeloid Leukemia

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Role of MBD4 Mutation in Neoplastic Evolution of Acute Myeloid Leukemia

Demonstration That Loss of TET2 Impairs DNA Mismatch Repair Resulting in Clonally Restricted Genomic Instability

Heightened Endoplasmic-Reticulum Stress Is a Targetable Vulnerability of Malignant Plasma Cells in Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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