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Yvonne Parker
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Journal Articles

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Daniel J Vail, Dongxu Jiang, Kunho Chung, Yahan Zhang, Sophia Martinez, Luca Guarnera, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 1278.
https://doi.org/10.1182/blood-2024-211683
Published: 2024
Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2918.
https://doi.org/10.1182/blood-2024-207470
Published: 2024
Journal Articles

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Dongxu Jiang, Daniel J Vail, Yahan Zhang, Raziullah Khan, Anand Tiwari, Simon Schlanger, Kunho Chung, Cassandra Gilmour, Xiaorong Gu, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2664.
https://doi.org/10.1182/blood-2024-211363
Published: 2024
Journal Articles

Heightened Endoplasmic-Reticulum Stress Is a Targetable Vulnerability of Malignant Plasma Cells in Multiple Myeloma

Danai Dima, Metis Hasipek, Divya Jyoti Singh, Dongxu Jiang, Anand D. Tiwari, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Jianjun Zhao, Kenneth H. Shain, Jack Khouri, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2022) 140 (Supplement 1): 7100–7101.
https://doi.org/10.1182/blood-2022-169516
Published: 2022
Journal Articles

Germline MPO Variants Predispose to Myeloid Neoplasia: Potential Mechanisms Suggested By In Vivo and in Vitro Studies

Sunisa Kongkiatkamon, Laila Terkawi, Vera Adema, Yihong Guan, Metis Hasipek, Tatiana Dombrovski, Milo Co, Wencke Walter, Cassandra M Kerr, Yasunobu Nagata, Hassan Awada, Yvonne Parker, Stephan Hutter, Simona Pagliuca, Carmelo Gurnari, Manja Meggendorfer, Daniel Lindner, Valeria Visconte, Torsten Haferlach, Thomas LaFramboise, Babal K. Jha, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2021) 138 (Supplement 1): 3662.
https://doi.org/10.1182/blood-2021-149598
Published: 2021
Journal Articles

Pharmacologic Normalization of Altered Transcriptome of SF3B1 Mutant Myeloid Neoplasia

Valeria Visconte, PhD, Vera Adema, PhD, Anand D. Tiwari, PhD, Cassandra M Kerr, MS, Hassan Awada, Bartlomiej Przychodzen, Allison Noe, Rachel Toth, Christina Snider, Yvonne Parker, Yuriy Fedorov, Drew Adams, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Jennifer S. Carew, PhD, Heesun J. Rogers, MD PhD, Daniel J. Lindner, Mikkael A. Sekeres, MD MS, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 564.
https://doi.org/10.1182/blood-2019-129189
Published: 2019
Journal Articles

Hypomethylating Agent 5-Azacytidine Sensitizes Peripheral T-Cell Lymphoma to SLAMF7-Targeting Therapeutic Antibody, Elotuzumab

Neetha Parameswaran, PhD, Xiaoxian Zhao, PhD, Juraj Bodo, PhD, Lisa Durkin, Yvonne Parker, Daniel Lindner, MD PhD, Eric D. Hsi, MD, Deepa Jagadeesh, MDMPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 1515.
https://doi.org/10.1182/blood-2019-131800
Published: 2019
Journal Articles

Reversible TET Inhibitor As a Hematopoietic Stem Cell Booster: A Novel Strategy to Improve Stem Cell Function

Sunisa Kongkiatkamon, Yihong Guan, PhD, Anand Tiwari, Phillip J Maciejewski, Dale Grabowski, BS, Sergei Vatolin, PhD, Vera Adema, PhD, Cassandra M Kerr, MS, Yasunobu Nagata, MD PhD, Milo Co, Christina Snider, Hassan Awada, Jibran Durrani, Yvonne Parker, Daniel J. Lindner, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2472.
https://doi.org/10.1182/blood-2019-129056
Published: 2019
Journal Articles

Therapeutic Applications of a Unique Calcium Channel Blocker to Target SF3B1 MDS

Sunisa Kongkiatkamon, Anand Tiwari, Vera Adema, PhD, Cassandra M Kerr, MS, Bartlomiej Przychodzen, Hassan Awada, Jibran Durrani, Yvonne Parker, Drew Adams, Yuriy Fedorov, Hetty E. Carraway, MD MBA, Chao-Yie Yang, Mikkael A. Sekeres, MD MS, Daniel J. Lindner, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 881.
https://doi.org/10.1182/blood-2019-128671
Published: 2019
Journal Articles

Lessons from Nature: A Novel Class of TET Inhibitors for TET2 Mutant Associated Diseases

Yihong Guan, Anand D. Tiwari, PhD, Metis Hasipek, PhD, Dale Grabowski, BS, Yvonne Parker, Cassandra M. Hirsch, Amy C Graham, BS, MS, Yasunobu Nagata, Bartlomiej P. Przychodzen, Aziz Nazha, Daniel Lindner, MD PhD, Tomas Radivoyevitch, PhD, James G Phillips, PhD, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2018) 132 (Supplement 1): 4345.
https://doi.org/10.1182/blood-2018-99-117186
Published: 2018
Journal Articles

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Valeria Visconte, PhD, Bartlomiej P. Przychodzen, Vera Adema, PhD, Cassandra M. Hirsch, Allison Noe, Rachel Toth, Christina Snider, BA, Hassan Awada, MD, Amy C Graham, BS, MS, Yvonne Parker, Yuriy Fedorov, Drew Adams, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Tomas Radivoyevitch, Heesun J. Rogers, MD PhD, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Jennifer S. Carew, PhD, Daniel Lindner, MD PhD, Richard A Padgett, Mikkael A. Sekeres, MD MS, James G Phillips, PhD, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2018) 132 (Supplement 1): 211.
https://doi.org/10.1182/blood-2018-99-116411
Published: 2018
Journal Articles

LUC7L2 Is a Novel RNA-Splicing Regulatory Factor Mutated in Myelodysplastic Syndromes

Courtney Hershberger, BS, James Hiznay, Rosemary Dietrich, Xiaorong Gu, PhD, Cassandra M. Hirsch, Amy Graham, BS, MS, Bartlomiej P. Przychodzen, Valeria Visconte, PhD, Vera Adema, PhD, Yvonne Parker, Hetty E. Carraway, MD MBA, Tomas Radivoyevitch, PhD, Mikkael A. Sekeres, MD MS, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, Richard A Padgett
Journal: Blood
Blood (2018) 132 (Supplement 1): 3073.
https://doi.org/10.1182/blood-2018-99-112838
Published: 2018
Journal Articles

Targeting Autophagy in Myelodysplastic Syndromes

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Bartlomiej P Przychodzen, MSc, Kevin R. Kelly, MD PhD, Mei Yin, Yvonne Parker, Michael J. Clemente, M.S., John Barnard, PhD, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Daniel Lindner, Heesun J Rogers, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP, Jennifer S. Carew, PhD
Journal: Blood
Blood (2016) 128 (22): 4295.
https://doi.org/10.1182/blood.V128.22.4295.4295
Published: 2016
Journal Articles

Genetic and Epigenetic Defects in the Autophagy Machinery in Myelodysplastic Syndromes

Valeria Visconte, PhD, Bartlomiej P Przychodzen, MSc, Steffan T. Nawrocki, PhD, Swapna Thota, MD, Kevin R. Kelly, MD PhD, Bhumika Patel, MD, Cassandra M. Hirsch, BSc, Hetty E. Carraway, MD MBA, Yvonne Parker, Daniel Lindner, Mikkael A. Sekeres, MD MS, Heesun J Rogers, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Jennifer S. Carew, PhD
Journal: Blood
Blood (2016) 128 (22): 4301.
https://doi.org/10.1182/blood.V128.22.4301.4301
Published: 2016
Journal Articles

A Novel in Vitro Three Organ System Assay Identifies a Small Molecule Ubiquitin Analog with in Vivo Activity Against Myeloma

Sergei Vatolin, PhD, James G Phillips, PhD, Shravya Govindgari, Dale Grabowski, Yvonne Parker, Daniel Lindner, MD PhD, Claudiu Cotta, MD PhD, Frederic J. Reu, MD
Journal: Blood
Blood (2014) 124 (21): 2085.
https://doi.org/10.1182/blood.V124.21.2085.2085
Published: 2014
Journal Articles

Inhibition Of JAK-STAT Pathway As a Therapeutic Option For Myelofibrosis Associated Pulmonary Hypertension

Ali Tabarroki, MD, Daniel Lindner, Valeria Visconte, PhD, Li Zhang, Edy Hasrouni, Yvonne Parker, Heesun J. Rogers, MD, PhD, Tracy Cinalli, RN, Kristin Dodd, RN, Gina Rupp, Hien Kim Duong, MD, Alan E. Lichtin, Matt Kalaycio, MD, Mikkael A. Sekeres, MD, MS, Anjali S. Advani, MD, Betty K. Hamilton, MD, Sudipto Mukherjee, MD, PhD, MPH, Yogen Saunthararajah, MD, Stavros E Mountantonakis, Gustavo A Heresi, Ramon V. Tiu, MD
Journal: Blood
Blood (2013) 122 (21): 1585.
https://doi.org/10.1182/blood.V122.21.1585.1585
Published: 2013
Journal Articles

Splicing Factor 3b Subunit 1 (SF3B1) Heterozygous Mice Manifest a Hematologic Phenotype Similar To Low Risk Myelodysplastic Syndromes With Ring Sideroblasts

Valeria Visconte, PhD, Heesun J. Rogers, MD, PhD, Ali Tabarroki, MD, Li Zhang, Yvonne Parker, Edy Hasrouni, Reda Z Mahfouz, MD/PhD, Quteba Ebrahem, MD, Kyoichi Isono, Haruhiko Koseki, Anjali S. Advani, MD, Yogen Saunthararajah, M.D., Mikkael A. Sekeres, MD, MS, Daniel Lindner, John Barnard, Ramon V. Tiu, MD
Journal: Blood
Blood (2013) 122 (21): 259.
https://doi.org/10.1182/blood.V122.21.259.259
Published: 2013
Journal Articles

A Novel Small Molecule with Epigenetic Activity Prolongs Survival in a Mouse Model of Multiple Myeloma Refractory to Standard Drugs

Sergei Vatolin, PhD, Khan Nazeer Shahper, PhD, Yvonne Parker, Daniel Lindner, Frederic J. Reu, MD
Journal: Blood
Blood (2011) 118 (21): 5121.
https://doi.org/10.1182/blood.V118.21.5121.5121
Published: 2011