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Journal Articles

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Jill Durkin, Daniel Vail, Dongxu Jiang, Yahan Zhang, Simon Schlanger, Jaroslaw Maciejewski, Thomas Laframboise, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 5727.
https://doi.org/10.1182/blood-2024-207943
Published: 2024
Journal Articles

Understanding the Molecular Mechanism of Plasma Cell Clonality and Disease Evolution in Light Chain Amyloidosis

Yahan Zhang, Sandra Mazzoni, Simon Schlanger, Jack Khouri, Louis Williams, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 6820.
https://doi.org/10.1182/blood-2024-208082
Published: 2024
Journal Articles

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Dongxu Jiang, Yahan Zhang, Xiaorong Gu, Daniel J Vail, Jill Durkin, Simon Schlanger, J. Joseph Melenhorst, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 40.
https://doi.org/10.1182/blood-2024-211171
Published: 2024
Journal Articles

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Dongxu Jiang, Daniel J Vail, Yahan Zhang, Raziullah Khan, Anand Tiwari, Simon Schlanger, Kunho Chung, Cassandra Gilmour, Xiaorong Gu, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2664.
https://doi.org/10.1182/blood-2024-211363
Published: 2024
Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 2918.
https://doi.org/10.1182/blood-2024-207470
Published: 2024
Journal Articles

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Xiaorong Gu, Songa Bae, Yahan Zhang, Nakisha D Williams, Dongxu Jiang, Simon Schlanger, Valeria Visconte, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2024-208348
Published: 2024
Journal Articles

Loss of TET2 Creates a Distinct Immunopeptidome in Acute Myeloid Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Daniel Vail, Simon Schlanger, Jaroslaw Maciejewski, Babal K. Jha
Journal: Blood
Blood (2024) 144 (Supplement 1): 4154.
https://doi.org/10.1182/blood-2024-208025
Published: 2024
Journal Articles

Loss of Function MBD4 Mutation Impairs DNA Repair in Association with TET2 in Acute Myeloid Leukemia

Naomi Kawashima, Dongxu Jiang, Daniel Vail, Divya Jyoti Singh, Xiaorong Gu, Simon Schlanger, Carmelo Gurnari, Yasuo Kubota, Brittany L Stewart, Valeria Visconte, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 1371.
https://doi.org/10.1182/blood-2023-182142
Published: 2023
Journal Articles

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Xiaorong Gu, Dongxu Jiang, Simon Schlanger, Nakisha D Williams, Divya Jyoti Singh, Daniel Vail, Jill Durkin, Yahan Zhang, Valeria Visconte, Jaroslaw P. Maciejewski, Babal Kant Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2747.
https://doi.org/10.1182/blood-2023-189228
Published: 2023
Journal Articles

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Divya Jyoti Singh, Metis Hasipek, Dongxu Jiang, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Simon Schlanger, Xiaorong Gu, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah, Hetty E. Carraway, Babal Kant Jha
Journal: Blood
Blood (2023) 142 (Supplement 1): 1422.
https://doi.org/10.1182/blood-2023-189274
Published: 2023