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Journal Articles

ER-resident chaperon protein disulfide isomerase PDIA1 inhibition restricts and eliminate aberrant plasma cells

Raziullah Khan, Anand Tiwari, Mamta Sumi, Yahan Zhang, Daniel Vail, Dongxu Jiang, Sandra Mazzoni, Louis Williams, Babal Jha

Blood (2025) 146 (Supplement 1): 7488.

https://doi.org/10.1182/blood-2025-7488

Published: 2025

Journal Articles

Dysregulated proteasome proteostasis acts as a driver of light chain amyloidosis

Sandra Mazzoni, Babal Jha, Louis Williams, Jack Khouri, Christy Samaras, Shahzad Raza, Faiz Anwer, Jason Valent, Arda Durmaz, Yahan Zhang, Kacey O'Donnell

Blood (2025) 146 (Supplement 1): 7473.

https://doi.org/10.1182/blood-2025-7473

Published: 2025

Journal Articles

Aberrant clonal plasma cells bypass the proteasome proteostasis by endoplasmic reticulum associated protein degradation

Yahan Zhang, Sandra Mazzoni, Arda Durmaz, Kacey O'Donnell, Christy Samaras, Faiz Anwer, Shahzad Raza, Jason Valent, Jack Khouri, Louis Williams, Babal Jha

Blood (2025) 146 (Supplement 1): 7476.

https://doi.org/10.1182/blood-2025-7476

Published: 2025

Journal Articles

Chromodomain helicase DNA binding protein CHD2 interacts with TET2 and regulates lineage defining transcription in hematopoietic stem and progenitor cells

Songa Bae, Xiaorong Gu, Mamta Sumi, Dongxu Jiang, Daniel Vail, Yahan Zhang, Kacey O'Donnell, Yogen Saunthararajah, Jaroslaw Maciejewski, Babal Jha

Blood (2025) 146 (Supplement 1): 3237.

https://doi.org/10.1182/blood-2025-3237

Published: 2025

Journal Articles

Real-world effectiveness of l-glutamine in Texas Medicaid patients with sickle cell disease

Yahan Zhang, Hyeun Ah Kang, Kristin M. Richards, Kenneth Lawson, Alicia Chang, Mark Udden

Blood (2025) 146 (Supplement 1): 2665.

https://doi.org/10.1182/blood-2025-2665

Published: 2025

Journal Articles

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Xiaorong Gu, Songa Bae, Yahan Zhang, Nakisha D Williams, Dongxu Jiang, Simon Schlanger, Valeria Visconte, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 4159.

https://doi.org/10.1182/blood-2024-208348

Published: 2024

Journal Articles

Loss of TET2 Creates a Distinct Immunopeptidome in Acute Myeloid Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Daniel Vail, Simon Schlanger, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 4154.

https://doi.org/10.1182/blood-2024-208025

Published: 2024

Journal Articles

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Dongxu Jiang, Yahan Zhang, Xiaorong Gu, Daniel J Vail, Jill Durkin, Simon Schlanger, J. Joseph Melenhorst, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 40.

https://doi.org/10.1182/blood-2024-211171

Published: 2024

Journal Articles

Understanding the Molecular Mechanism of Plasma Cell Clonality and Disease Evolution in Light Chain Amyloidosis

Yahan Zhang, Sandra Mazzoni, Simon Schlanger, Jack Khouri, Louis Williams, Babal K. Jha

Blood (2024) 144 (Supplement 1): 6820.

https://doi.org/10.1182/blood-2024-208082

Published: 2024

Journal Articles

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Dongxu Jiang, Daniel J Vail, Yahan Zhang, Raziullah Khan, Anand Tiwari, Simon Schlanger, Kunho Chung, Cassandra Gilmour, Xiaorong Gu, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2664.

https://doi.org/10.1182/blood-2024-211363

Published: 2024

Journal Articles

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Xiaorong Gu, Yahan Zhang, Songa Bae, Dongxu Jiang, Nakisha D Williams, Daniel Vail, Simon Schlanger, Jill Durkin, Yvonne Parker, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 2918.

https://doi.org/10.1182/blood-2024-207470

Published: 2024

Journal Articles

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Jill Durkin, Daniel Vail, Dongxu Jiang, Yahan Zhang, Simon Schlanger, Jaroslaw Maciejewski, Thomas Laframboise, Babal K. Jha

Blood (2024) 144 (Supplement 1): 5727.

https://doi.org/10.1182/blood-2024-207943

Published: 2024

Journal Articles

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Daniel J Vail, Dongxu Jiang, Kunho Chung, Yahan Zhang, Sophia Martinez, Luca Guarnera, Yvonne Parker, J. Joseph Melenhorst, Daniel Lindner, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 1278.

https://doi.org/10.1182/blood-2024-211683

Published: 2024

Journal Articles

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Divya Jyoti Singh, Metis Hasipek, Dongxu Jiang, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Simon Schlanger, Xiaorong Gu, Jaroslaw P. Maciejewski, Yogenthiran Saunthararajah, Hetty E. Carraway, Babal Kant Jha

Blood (2023) 142 (Supplement 1): 1422.

https://doi.org/10.1182/blood-2023-189274

Published: 2023

Journal Articles

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Xiaorong Gu, Dongxu Jiang, Simon Schlanger, Nakisha D Williams, Divya Jyoti Singh, Daniel Vail, Jill Durkin, Yahan Zhang, Valeria Visconte, Jaroslaw P. Maciejewski, Babal Kant Jha

Blood (2023) 142 (Supplement 1): 2747.

https://doi.org/10.1182/blood-2023-189228

Published: 2023

Journal Articles

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Dongxu Jiang, Yihong Guan, Shinjini Ganguly, Aysegul Balyimez, Andrew Muskara, Divya Jyoti Singh, Simona Pagliuca, Daniel Vail, Yahan Zhang, Jill Durkin, Naomi Kawashima, Xiaorong Gu, Carmelo Gurnari, Jaroslaw P. Maciejewski, Omar Mian, Babal K. Jha

Blood (2023) 142 (Supplement 1): 2766.

https://doi.org/10.1182/blood-2023-186924

Published: 2023

Journal Articles

Age-related Impact of the CDC's 2016 Guideline for Prescribing Opioids for Chronic Pain on Opioid Prescribing Levels and Health Outcomes among the Patients with Sickle Cell Disease

Hyeun Ah Kang, Yahan Zhang, Jamie Barner, Kenneth I Ataga

Blood (2022) 140 (Supplement 1): 5112–5113.

https://doi.org/10.1182/blood-2022-165436

Published: 2022

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ER-resident chaperon protein disulfide isomerase PDIA1 inhibition restricts and eliminate aberrant plasma cells

Dysregulated proteasome proteostasis acts as a driver of light chain amyloidosis

Aberrant clonal plasma cells bypass the proteasome proteostasis by endoplasmic reticulum associated protein degradation

Chromodomain helicase DNA binding protein CHD2 interacts with TET2 and regulates lineage defining transcription in hematopoietic stem and progenitor cells

Real-world effectiveness of l-glutamine in Texas Medicaid patients with sickle cell disease

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Loss of TET2 Creates a Distinct Immunopeptidome in Acute Myeloid Leukemia

TET2 Regulates Stability of Mismatch Repair Protein MSH6 and Helps Maintain Genomic Stability Independent of Its Dioxygenase Function

Understanding the Molecular Mechanism of Plasma Cell Clonality and Disease Evolution in Light Chain Amyloidosis

Low Regimen Therapeutic Strategies to Mitigate TET2 Mutant Clonal Hematopoiesis

Developing a Therapeutic Strategy for Targeting Metabolic Vulnerability of TET2 Mutant Leukemia

Rap Guanine Nucleotide Exchange Factor RAPGEF5 Is a Novel Tumor Suppressor in 7/del7q Myeloid Neoplasia

Age-Related Cellular Factors Facilitate TET2 Mutant Clonal Hematopoiesis

Fatty Acid Binding Protein FABP5 Inhibition Activates Retinoic Acid Signaling and Induces Differentiation in Acute Myeloid Leukemia

Metabolic Signatures and Pathway Rewiring in TET2-Mutated Myeloid Neoplasia

Methyl-CpG Binding Domain Protein MBD2 Is a Targetable Vulnerability in TET2 Mutant Myeloid Neoplasia

Age-related Impact of the CDC's 2016 Guideline for Prescribing Opioids for Chronic Pain on Opioid Prescribing Levels and Health Outcomes among the Patients with Sickle Cell Disease

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American Society of Hematology

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