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Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour

Blood (2023) 142 (25): 2175–2191.

https://doi.org/10.1182/blood.2022015752

Published: 2023

Includes: Supplemental data

Journal Articles

AML Associated Mesenchymal Stroma Cells Support Growth of AML Cells As a Result of Activated Notch Signaling and This Can be Targeted By Dexamethasone

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-134177

Published: 2020

Journal Articles

HIF-1α Promotes Cbfbeta-SMMHC-Induced Acute Myeloid Leukemia Development

Benedikt W. Pelzer, Anita Hollenbeck, PhD, Stefanie Weber, Bertram Opalka, PhD, Lucio H. Castilla, PhD, Ulrich Dührsen, MD, Joachim R. Göthert, MD

Blood (2016) 128 (22): 1559.

https://doi.org/10.1182/blood.V128.22.1559.1559

Published: 2016

Journal Articles

the Role of MSCs in the Development of Acute Myeloid Leukemia

Yahya Saleh Al-Matary, MSc, Lacramioara Botezatu, PhD, Robert Fernando Lams, Aniththa Thivakaran, MSc, Renata Köster, Judith Schütte, PhD, Ulrich Dührsen, MD, Bertram Opalka, PhD, Cyrus Khandanpour, MD

Blood (2016) 128 (22): 2669.

https://doi.org/10.1182/blood.V128.22.2669.2669

Published: 2016

Journal Articles

GFI1b As a Novel Oncosuppressor in AML

Aniththa Thivakaran, M.Sc., Lacramioara Botezatu, PhD, Judith Maria Hoenes, M.Sc., Yahya Saleh Al-Matary, MSc, Nadine Olberding, B.Sc, Judith Schütte, PhD, Renata Köster, Bertram Opalka, PhD, Ulrich Dührsen, MD, Cyrus Khandanpour, MD

Blood (2016) 128 (22): 2717.

https://doi.org/10.1182/blood.V128.22.2717.2717

Published: 2016

Journal Articles

Function of Growth Factor Independence 1 (GFI1) in the Polarization AML -Associated Stroma

Lacramioara Botezatu, PhD, Yahya S. A. Al-Matary, Bertram Opalka, PhD, Jan Dürig, PD Dr., Thomas Schroeder, MD, Rainer Haas, MD, Ulrich Dührsen, Cyrus Khandanpour, MD

Blood (2014) 124 (21): 4366.

https://doi.org/10.1182/blood.V124.21.4366.4366

Published: 2014

Journal Articles

Activation of the Hypoxia-Inducible Factor Pathway Expands Early Thymic Progenitors

Anita Hollenbeck, Stefanie Weber, Kathrin Händschke, PhD, Mandy Necke, Bertram Opalka, PhD, Ulrich Dührsen, MD, Joachim Rudolf Göthert, MD

Blood (2014) 124 (21): 2896.

https://doi.org/10.1182/blood.V124.21.2896.2896

Published: 2014

Journal Articles

Gfi1 As a Novel Prognostic Marker and Tumor Suppressor In Acute Myeloid Leukemia

Blood (2013) 122 (21): 2516.

https://doi.org/10.1182/blood.V122.21.2516.2516

Published: 2013

Journal Articles

Gfi1b-A Novel Tumor Suppressor In Acute Myeloid Leukemia

Lacramioara Botezatu, Phd, Judith Hönes, M.Sc., Amos Zeller, Lars C. Michel, Andre Görgens, Phd, Klaus Lennartz, Renata Köster, Bertram Opalka, PhD, Bernd Giebel, Ulrich Dührsen, MD, Cyrus Khandanpour, M.D.

Blood (2013) 122 (21): 3795.

https://doi.org/10.1182/blood.V122.21.3795.3795

Published: 2013

Journal Articles

Deletion Of The Von Hippel-Lindau Gene Interferes With The Development Of Peripheral B-Cell Subsets

Kathrin Händschke, Stefanie Weber, Mandy Necke, Anita Hollenbeck, Bertram Opalka, PhD, Ulrich Dührsen, MD, Joachim Rudolf Göthert, MD

Blood (2013) 122 (21): 3666.

https://doi.org/10.1182/blood.V122.21.3666.3666

Published: 2013

Journal Articles

AML Bone Marrow Microenvironment Impairs Dendritic Cell Maturation and Antigen Presentation

Bettina Wagner, Vera Rebmann, Tobias May, Ulrich Duehrsen, Joachim Rudolf Göthert, Peter A Horn, Bertram Opalka

Blood (2012) 120 (21): 1491.

https://doi.org/10.1182/blood.V120.21.1491.1491

Published: 2012

Journal Articles

Heterogeneous Interactions of Leukemic and Control Bone Marrow Stroma Cells with an AML Cell Line and AML Leukemic Blasts.

Ulrike Buttkereit, Sana Mohamad, Monika Lindemann, Joachim R. Goethert, Bertram Opalka, Jan Duerig, Ulrich Duehrsen

Blood (2010) 116 (21): 1047.

https://doi.org/10.1182/blood.V116.21.1047.1047

Published: 2010

Journal Articles

Cytomegalovirus Reduces the Relapse Risk for Acute Leukemia After Transplant: There Is a Virus-Versus-Leukemia Effect.

Ahmet H Elmaagacli, Monika Lindemann, Bertram Opalka, Michael Koldehoff, Tania Gromke, Hellmut Ottinger, Rudolf S. Ross, Sebastian Bauer, Inken Hilgendorf, MD, Dietrich W. Beelen, MD

Blood (2009) 114 (22): 2261.

https://doi.org/10.1182/blood.V114.22.2261.2261

Published: 2009

Journal Articles

Cytomegalovirus Drives Acute Myeloid Leukemia Cells in Apoptosis and Reduces Thereby Markedly the Risk for Relapse after Transplant

Ahmet H Elmaagacli, Michael Koldehoff, Tania Gromke, Rudolf S Ross, Rudolf Trenschel, Sebastian Bauer, Bertram Opalka, Dietrich W Beelen

Blood (2008) 112 (11): 3301.

https://doi.org/10.1182/blood.V112.11.3301.3301

Published: 2008

Journal Articles

Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model

Ina Rattmann, Veronika Kleff, Ursula R. Sorg, Walter Bardenheuer, Annette Brueckner, Ralf A. Hilger, Bertram Opalka, Siegfried Seeber, Michael Flasshove, Thomas Moritz

Blood (2006) 108 (9): 2965–2971.

https://doi.org/10.1182/blood-2006-03-011734

Published: 2006

Journal Articles

Gene Transfer of Cytidine Deaminase (CDD) Protects from Cytidine Analogs in an In Vivo Murine Transplant Model.

Ina Rattmann, Ursula R. Sorg, Annette Brueckner, Bertram Opalka, Michael Flasshove, Thomas Moritz

Blood (2005) 106 (11): 3060.

https://doi.org/10.1182/blood.V106.11.3060.3060

Published: 2005

Journal Articles

Therapy-Associated Immunosuppression and Opportunistic Infections in Multiple Myeloma Patients.

Philipp Schutt, Dieter Brandhorst, Werner Stellberg, Miriam Poser, Peter Ebeling, Siemke Muller, Ulrike Buttkereit, Bertram Opalka, Monika Lindemann, Hans Grosse-Wilde, Siegfried Seeber, Thomas Moritz, Mohammad R. Nowrousian

Blood (2005) 106 (11): 5137.

https://doi.org/10.1182/blood.V106.11.5137.5137

Published: 2005

Journal Articles

The Risk of Residual Molecular and Cytogenetic Disease in Patients With Philadelphia-Chromosome Positive First Chronic Phase Chronic Myelogenous Leukemia Is Reduced After Transplantation of Allogeneic Peripheral Blood Stem Cells Compared With Bone Marrow

Ahmet H. Elmaagacli, Dietrich W. Beelen, Bertram Opalka, Siegfried Seeber, Ulrich W. Schaefer

Blood (1999) 94 (2): 384–389.

https://doi.org/10.1182/blood.V94.2.384

Published: 1999

Journal Articles

Detection of AML1/ETO Fusion Transcripts in Patients With t(8; 21) Acute Myeloid Leukemia After Allogeneic Bone Marrow Transplantation or Peripheral Blood Progenitor Cell Transplantation

Ahmet H. Elmaagacli, Dietrich W. Beelen, Jitka Stockova, Susanne Trzensky, Melanie Kroll, Ulrich W. Schaefer, Christina Stein, Bertram Opalka

Blood (1997) 90 (8): 3230–3231.

https://doi.org/10.1182/blood.V90.8.3230

Published: 1997

NARROW

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

AML Associated Mesenchymal Stroma Cells Support Growth of AML Cells As a Result of Activated Notch Signaling and This Can be Targeted By Dexamethasone

HIF-1α Promotes Cbfbeta-SMMHC-Induced Acute Myeloid Leukemia Development

the Role of MSCs in the Development of Acute Myeloid Leukemia

GFI1b As a Novel Oncosuppressor in AML

Function of Growth Factor Independence 1 (GFI1) in the Polarization AML -Associated Stroma

Activation of the Hypoxia-Inducible Factor Pathway Expands Early Thymic Progenitors

Gfi1 As a Novel Prognostic Marker and Tumor Suppressor In Acute Myeloid Leukemia

Gfi1b-A Novel Tumor Suppressor In Acute Myeloid Leukemia

Deletion Of The Von Hippel-Lindau Gene Interferes With The Development Of Peripheral B-Cell Subsets

AML Bone Marrow Microenvironment Impairs Dendritic Cell Maturation and Antigen Presentation

Heterogeneous Interactions of Leukemic and Control Bone Marrow Stroma Cells with an AML Cell Line and AML Leukemic Blasts.

Cytomegalovirus Reduces the Relapse Risk for Acute Leukemia After Transplant: There Is a Virus-Versus-Leukemia Effect.

Cytomegalovirus Drives Acute Myeloid Leukemia Cells in Apoptosis and Reduces Thereby Markedly the Risk for Relapse after Transplant

Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model

Gene Transfer of Cytidine Deaminase (CDD) Protects from Cytidine Analogs in an In Vivo Murine Transplant Model.

Therapy-Associated Immunosuppression and Opportunistic Infections in Multiple Myeloma Patients.

The Risk of Residual Molecular and Cytogenetic Disease in Patients With Philadelphia-Chromosome Positive First Chronic Phase Chronic Myelogenous Leukemia Is Reduced After Transplantation of Allogeneic Peripheral Blood Stem Cells Compared With Bone Marrow

Detection of AML1/ETO Fusion Transcripts in Patients With t(8; 21) Acute Myeloid Leukemia After Allogeneic Bone Marrow Transplantation or Peripheral Blood Progenitor Cell Transplantation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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