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Journal Articles

Innovative Hematopoietic Gene-Therapy Concepts for Hereditary Pulmonary Alveolar Proteinosis Utilizing Hematopoietic Stem Cell Derived Macrophages

Nico Lachmann, PhD, Christine Happle, MD, Takuji Suzuki, MD, Miriam Hetzel, Kevin A. Link, PhD, Adele Mucci, Paritha Arumugam, PhD, Jens Bankstahl, PhD, Dagmar Dilloo, MD, Punam Malik, MD, Carolyn Lutzko, PhD, Axel Schambach, MD PhD, Bruce Colston Trapnell, MD, Gesine Hansen, MD, Thomas Moritz, MD

Blood (2015) 126 (23): 4417.

https://doi.org/10.1182/blood.V126.23.4417.4417

Published: 2015

Journal Articles

IL-3 Specifies Early Hematopoietic Development from Human iPSCs and Synergizes with M-CSF and G-CSF on Myeloid Differentiation

Nico Lachmann, PhD, Mania Ackermann, Eileen Frenzel, Christine Happle, MD PhD, Olga Klimenkova, PhD, Sebastian Brennig, Doreen Lüttge, Theresa Buchegger, Sabina Janciauskiene, MD, Julia Skokowa, MD PhD, Dagmar Dilloo, MD, Thomas Moritz, MD

Blood (2014) 124 (21): 4308.

https://doi.org/10.1182/blood.V124.21.4308.4308

Published: 2014

Journal Articles

The Ubiquitous Chromatin Opening Element (UCOE) Enhances Lentiviral Cytidine Deaminase (CDD) Expression and Drug Resistance During Hematopoietic Differentiation of Murine Induced Pluripotent Stem Cells (iPSCs),

Nils Pfaff, Nico Lachmann, Mania Ackermann, Saskia Kohlscheen, Christian Brendel, Michael Flasshove, MD, Axel Schambach, MD PhD, Thomas Moritz, MD

Blood (2011) 118 (21): 4179.

https://doi.org/10.1182/blood.V118.21.4179.4179

Published: 2011

Journal Articles

Doxycycline Regulatable Expression of Cytidine Deaminase Mediates Myeloprotection and Avoids Lymphotoxicity in a Murine Transplant Model

Nico Lachmann, Sebastian Brennig, Nils Pfaff, Heiko Schermeier, Axel Schambach, MD PhD, Christopher Baum, MD, Thomas Moritz, MD

Blood (2011) 118 (21): 2054.

https://doi.org/10.1182/blood.V118.21.2054.2054

Published: 2011

Journal Articles

Very High Expression of MGMT(P140K) Paradoxically Impairs Proliferation, In Vivo Selection and Protection of Transduced Hematopoietic Stem Cells.

Michael D. Milsom, PhD, Chad E. Harris, Axel Schambach, MD, PhD, Emily Broun, Moran Jerabek-Willemsen, Christopher Baum, MD, Thomas Moritz, MD, Geoffrey Margison, PhD, Jürgen Thomale, PhD, David A. Williams, MD

Blood (2007) 110 (11): 2588.

https://doi.org/10.1182/blood.V110.11.2588.2588

Published: 2007

Journal Articles

The Expression of the GTPase-Deficient, Hematopoietic-Specific RhoH GTPase Is Implicated in Development of Chronic Lymphocytic Leukemia (CLL).

Ina Rattmann, David Zhu, Carlo M. Croce, John C. Byrd, Yi Gu, Thomas Moritz, David A. Williams

Blood (2007) 110 (11): 339.

https://doi.org/10.1182/blood.V110.11.339.339

Published: 2007

Journal Articles

Distinct Phenotype of Chronic Lymphocytic Leukaemia (B-CLL) Cells Engrafting in NOD/SCID Mice.

Peter Ebeling, MD, Jan Durig, MD, Florian Grabellus, MD, Siegfried Seeber, MD, Ulrich Duehrsen, MD, Thomas Moritz, MD

Blood (2006) 108 (11): 2822.

https://doi.org/10.1182/blood.V108.11.2822.2822

Published: 2006

Journal Articles

Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model

Ina Rattmann, Veronika Kleff, Ursula R. Sorg, Walter Bardenheuer, Annette Brueckner, Ralf A. Hilger, Bertram Opalka, Siegfried Seeber, Michael Flasshove, Thomas Moritz

Blood (2006) 108 (9): 2965–2971.

https://doi.org/10.1182/blood-2006-03-011734

Published: 2006

Journal Articles

Highly Reproducible Engraftment of Chronic Lymphocytic Leukemia (B-CLL) Cells in NOD/SCID Mice.

Peter Ebeling, Jan Duerig, Florian Grabellus, Ulrich Duehrsen, Siegfried Seeber, Michael Flasshove, Thomas Moritz

Blood (2005) 106 (11): 52.

https://doi.org/10.1182/blood.V106.11.52.52

Published: 2005

Journal Articles

Gene Transfer of Cytidine Deaminase (CDD) Protects from Cytidine Analogs in an In Vivo Murine Transplant Model.

Ina Rattmann, Ursula R. Sorg, Annette Brueckner, Bertram Opalka, Michael Flasshove, Thomas Moritz

Blood (2005) 106 (11): 3060.

https://doi.org/10.1182/blood.V106.11.3060.3060

Published: 2005

Journal Articles

Therapy-Associated Immunosuppression and Opportunistic Infections in Multiple Myeloma Patients.

Philipp Schutt, Dieter Brandhorst, Werner Stellberg, Miriam Poser, Peter Ebeling, Siemke Muller, Ulrike Buttkereit, Bertram Opalka, Monika Lindemann, Hans Grosse-Wilde, Siegfried Seeber, Thomas Moritz, Mohammad R. Nowrousian

Blood (2005) 106 (11): 5137.

https://doi.org/10.1182/blood.V106.11.5137.5137

Published: 2005

Journal Articles

Comparison of Three Tests for Confirmation of the Diagnosis of Heparin Induced Thrombocytopenia.

Harry L. Messmore, MD, Abdul M. Choudhury, MD, Nancy J. Fabbrini, BS, Mary L. Bird, MD, Thomas Moritz, MS, Lizzy Thottapurathu, MS, William H. Wehrmacher, MD, Margaret Prechel, PhD, Jeanine M. Walenga, PhD, Thelma J. Crosby, MT, Betty C. Love, BS, Courtney A. Zarr, BS, Beth E. Griffin, BS, Sanober S. Balbale, BS

Blood (2004) 104 (11): 2075.

https://doi.org/10.1182/blood.V104.11.2075.2075

Published: 2004

Journal Articles

Clonal Analysis of Hematopoietic Stem Cells after Serial Transplantation of Animals Receiving MGMT P140K Gene Transduced Cells Following Chemotherapy.

Stephanie Laufs, Phd, Ursula Sorg, Phd, Veronika Kleff, Laila Gao, Michael Flasshove, MD, W. Jens Zeller, MD, Thomas Moritz, MD, Stefan Fruehauf, MD

Blood (2004) 104 (11): 1182.

https://doi.org/10.1182/blood.V104.11.1182.1182

Published: 2004

Journal Articles

Drug Resistance and In Vitro Selection of Human Hematopoietic Cells Transduced with Cytidine Deaminase.

Michael Flasshove, MD, Ina Rattmann, Kai Lehmberg, Walter Bardenheuer, PhD, Ursula R. Sorg, PhD, Siegfried Seeber, MD, Thomas Moritz, MD

Blood (2004) 104 (11): 5270.

https://doi.org/10.1182/blood.V104.11.5270.5270

Published: 2004

Journal Articles

Down-regulation of DNA repair in human CD34 + progenitor cells corresponds to increased drug sensitivity and apoptotic response

Claudia Buschfort-Papewalis, Thomas Moritz, Bernd Liedert, Jürgen Thomale

Blood (2002) 100 (3): 845–853.

https://doi.org/10.1182/blood-2002-01-0022

Published: 2002

NARROW

Innovative Hematopoietic Gene-Therapy Concepts for Hereditary Pulmonary Alveolar Proteinosis Utilizing Hematopoietic Stem Cell Derived Macrophages

IL-3 Specifies Early Hematopoietic Development from Human iPSCs and Synergizes with M-CSF and G-CSF on Myeloid Differentiation

The Ubiquitous Chromatin Opening Element (UCOE) Enhances Lentiviral Cytidine Deaminase (CDD) Expression and Drug Resistance During Hematopoietic Differentiation of Murine Induced Pluripotent Stem Cells (iPSCs),

Doxycycline Regulatable Expression of Cytidine Deaminase Mediates Myeloprotection and Avoids Lymphotoxicity in a Murine Transplant Model

Very High Expression of MGMT(P140K) Paradoxically Impairs Proliferation, In Vivo Selection and Protection of Transduced Hematopoietic Stem Cells.

The Expression of the GTPase-Deficient, Hematopoietic-Specific RhoH GTPase Is Implicated in Development of Chronic Lymphocytic Leukemia (CLL).

Distinct Phenotype of Chronic Lymphocytic Leukaemia (B-CLL) Cells Engrafting in NOD/SCID Mice.

Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model

Highly Reproducible Engraftment of Chronic Lymphocytic Leukemia (B-CLL) Cells in NOD/SCID Mice.

Gene Transfer of Cytidine Deaminase (CDD) Protects from Cytidine Analogs in an In Vivo Murine Transplant Model.

Therapy-Associated Immunosuppression and Opportunistic Infections in Multiple Myeloma Patients.

Comparison of Three Tests for Confirmation of the Diagnosis of Heparin Induced Thrombocytopenia.

Clonal Analysis of Hematopoietic Stem Cells after Serial Transplantation of Animals Receiving MGMT P140K Gene Transduced Cells Following Chemotherapy.

Drug Resistance and In Vitro Selection of Human Hematopoietic Cells Transduced with Cytidine Deaminase.

Down-regulation of DNA repair in human CD34 + progenitor cells corresponds to increased drug sensitivity and apoptotic response

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American Society of Hematology

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American Society of Hematology

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