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Kai Lehmberg
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Journal Articles

Diagnostic guidelines for familial hemophagocytic lymphohistiocytosis revisited

Clinical Trials & Observations
Jan-Inge Henter, Elena Sieni, Julia Eriksson, Elisabet Bergsten, Ida Hed Myrberg, Scott W. Canna, Maria Luisa Coniglio, Randy Q. Cron, Kate F. Kernan, Ashish R. Kumar, Kai Lehmberg, Francesca Minoia, Ahmed Naqvi, Angelo Ravelli, Yong-Min Tang, Matteo Bottai, Yenan T. Bryceson, AnnaCarin Horne, Michael B. Jordan
Journal: Blood
Blood (2024) 144 (22): 2308–2318.
https://doi.org/10.1182/blood.2024025077
Published: 2024
Includes: Supplemental data
Journal Articles

Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation

Clinical Trials & Observations
Svea Böhm, Katharina Wustrau, Jana Pachlopnik Schmid, Seraina Prader, Martina Ahlmann, Joanne Yacobovich, Rita Beier, Carsten Speckmann, Wolfgang Behnisch, Marianne Ifversen, Michael Jordan, Rebecca Marsh, Nora Naumann-Bartsch, Christine Mauz-Körholz, Manfred Hönig, Ansgar Schulz, Iwona Malinowska, Melissa Hines, Kim E. Nichols, Juana Gil-Herrera, Julie-An Talano, Bruce Crooks, Renata Formankova, Norbert Jorch, Shahrzad Bakhtiar, Ingrid Kühnle, Monika Streiter, Michaela Nathrath, Alexandra Russo, Matthias Dürken, Peter Lang, Caroline Lindemans, Jan-Inge Henter, Kai Lehmberg, Stephan Ehl
Journal: Blood
Blood (2024) 143 (10): 872–881.
https://doi.org/10.1182/blood.2023022281
Published: 2024
Includes: Supplemental data
Journal Articles

Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis

Giovanna Lucchini, Rebecca Marsh, Kimberly Gilmour, Austen Worth, Zohreh Nademi, Anupama Rao, Claire Booth, Persis Amrolia, Juliana Silva, Robert Chiesa, Robert Wynn, Kai Lehmberg, Itziar Astigarraga, Tayfun Güngör, Jan Stary, Despina Moshous, Marianne Ifversen, Daniel Zinn, Michael Jordan, Ashish Kumar, Takahiro Yasumi, Paul Veys, Kanchan Rao
Journal: Blood
Blood (2018) 132 (19): 2088–2096.
https://doi.org/10.1182/blood-2018-01-827485
Published: 2018
Includes: Supplemental data
Journal Articles

Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

CME Clinical Trials & Observations
Elisabet Bergsten, AnnaCarin Horne, Maurizio Aricó, Itziar Astigarraga, R. Maarten Egeler, Alexandra H. Filipovich, Eiichi Ishii, Gritta Janka, Stephan Ladisch, Kai Lehmberg, Kenneth L. McClain, Milen Minkov, Scott Montgomery, Vasanta Nanduri, Diego Rosso, Jan-Inge Henter
Journal: Blood
Blood (2017) 130 (25): 2728–2738.
https://doi.org/10.1182/blood-2017-06-788349
Published: 2017
Journal Articles

Treatment Dilemmas in Asymptomatic Children with Primary Haemophagocytic Lymphohistiocytosis

Giovanna Lucchini, MD, Rebecca A Marsh, Kimberly Gilmour, Austen Worth, Anupama Rao, Claire Booth, Persis J Amrolia, Juliana Silva, MD, Robert Chiesa, Robert Wynn, MD, Kai Lehmberg, Itziar Astigarraga, Tayfun Guengoer, Jan Stary, Despina Moshous, Marianne Ifversen, Stephan Ehl, Daniel Zinn, MD, Paul Veys, MD PhD, Kanchan Rao
Journal: Blood
Blood (2017) 130 (Supplement 1): 3564.
https://doi.org/10.1182/blood.V130.Suppl_1.3564.3564
Published: 2017
Journal Articles

Hemophagocytic Lymphohistiocytosis (HLH) in Langerhans Cell Histiocytosis (LCH): A Multicenter Retrospective Descriptional Study

Deepak Chellapandian, MD MBBS, Rui Zhang, MD, Michael Jeng, MD, Cor Van Den Bos, MD PhD, Vicente Santa-María López, MD, Kai Lehmberg, MD, Elena Sieni, MD, Yini Wang, MD, Taizo Allen Nakano, MD, James Williams, MD, Nicholas J. Fustino, MD, Itziar Astigarraga, MD, Ira Dunkel, MD, Qi An, Cheng Cheng, PhD, Sheila Weitzman, MB BCh, FRCP, Lillian Sung, MD PhD, Kim E. Nichols, MD
Journal: Blood
Blood (2016) 128 (22): 707.
https://doi.org/10.1182/blood.V128.22.707.707
Published: 2016
Journal Articles

Hemophagocytic Lymphohistiocytosis in Adults (aHLH): Results from the German HLH Registry

Sebastian Birndt, Thomas Schenk, MD, Frank M. Brunkhorst, MD, Georg Maschmeyer, MD, Frank Rothmann, MD, Thomas Weber, MD, Markus Müller, MD, Jens P. Panse, MD, Roland Schroers, MD, Jan Braess, MD, Norbert Frickhofen, MD, Gritta Janka, MD PhD, Kai Lehmberg, MD, Andreas Hochhaus, MD, Thomas Ernst, MD, Paul La Rosée, MD
Journal: Blood
Blood (2016) 128 (22): 2523.
https://doi.org/10.1182/blood.V128.22.2523.2523
Published: 2016
Journal Articles

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Bernd Hartz, Rebecca Marsh, Kanchan Rao, Jan-Inge Henter, Michael Jordan, Lisa Filipovich, Peter Bader, Rita Beier, Birgit Burkhardt, Roland Meisel, Ansgar Schulz, Beate Winkler, Michael H. Albert, Johann Greil, Gülsün Karasu, Wilhelm Woessmann, Selim Corbacioglu, Bernd Gruhn, Wolfgang Holter, Jörn-Sven Kühl, Peter Lang, Markus G. Seidel, Paul Veys, Alexandra Löfstedt, Sandra Ammann, Stephan Ehl, Gritta Janka, Ingo Müller, Kai Lehmberg
Journal: Blood
Blood (2016) 127 (25): 3281–3290.
https://doi.org/10.1182/blood-2015-12-684498
Published: 2016
Includes: Supplemental data
Journal Articles

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome

Sandra Ammann, Ansgar Schulz, Ingeborg Krägeloh-Mann, Nele M. G. Dieckmann, Klaus Niethammer, Sebastian Fuchs, Katja Martina Eckl, Roswitha Plank, Roland Werner, Janine Altmüller, Holger Thiele, Peter Nürnberg, Julia Bank, Anne Strauss, Horst von Bernuth, Udo zur Stadt, Samantha Grieve, Gillian M. Griffiths, Kai Lehmberg, Hans Christian Hennies, Stephan Ehl
Journal: Blood
Blood (2016) 127 (8): 997–1006.
https://doi.org/10.1182/blood-2015-09-671636
Published: 2016
Includes: Supplemental data
Journal Articles

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2

Birthe Jessen, Sebastian F. N. Bode, Sandra Ammann, Subarna Chakravorty, Graham Davies, Jana Diestelhorst, Melissa Frei-Jones, William A. Gahl, Bernadette R. Gochuico, Matthias Griese, Gillian Griffiths, Gritta Janka, Christoph Klein, Tamara Kögl, Karin Kurnik, Kai Lehmberg, Andrea Maul-Pavicic, Andrew D. Mumford, David Pace, Nima Parvaneh, Nima Rezaei, Geneviève de Saint Basile, Annette Schmitt-Graeff, Klaus Schwarz, Gulsun T. Karasu, Barbara Zieger, Udo zur Stadt, Peter Aichele, Stephan Ehl
Journal: Blood
Blood (2013) 121 (15): 2943–2951.
https://doi.org/10.1182/blood-2012-10-463166
Published: 2013
Includes: Supplemental data
Journal Articles

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

Clinical Trials & Observations
Rebecca A. Marsh, Kanchan Rao, Prakash Satwani, Kai Lehmberg, Ingo Müller, Dandan Li, Mi-Ok Kim, Alain Fischer, Sylvain Latour, Petr Sedlacek, Vincent Barlogis, Kazuko Hamamoto, Hirokazu Kanegane, Sam Milanovich, David A. Margolis, David Dimmock, James Casper, Dorothea N. Douglas, Persis J. Amrolia, Paul Veys, Ashish R. Kumar, Michael B. Jordan, Jack J. Bleesing, Alexandra H. Filipovich
Journal: Blood
Blood (2013) 121 (6): 877–883.
https://doi.org/10.1182/blood-2012-06-432500
Published: 2013
Journal Articles

Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5)

Clinical Trials & Observations
Julia Pagel, Karin Beutel, Kai Lehmberg, Florian Koch, Andrea Maul-Pavicic, Anna-Katharina Rohlfs, Abdullah Al-Jefri, Rita Beier, Lilian Bomme Ousager, Karoline Ehlert, Ute Gross-Wieltsch, Norbert Jorch, Bernhard Kremens, Arnulf Pekrun, Monika Sparber-Sauer, Ester Mejstrikova, Angela Wawer, Stephan Ehl, Udo zur Stadt, Gritta Janka
Journal: Blood
Blood (2012) 119 (25): 6016–6024.
https://doi.org/10.1182/blood-2011-12-398958
Published: 2012
Includes: Supplemental data
Journal Articles

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

Clinical Trials & Observations
Yenan T. Bryceson, Daniela Pende, Andrea Maul-Pavicic, Kimberly C. Gilmour, Heike Ufheil, Thomas Vraetz, Samuel C. Chiang, Stefania Marcenaro, Raffaella Meazza, Ilka Bondzio, Denise Walshe, Gritta Janka, Kai Lehmberg, Karin Beutel, Udo zur Stadt, Nadine Binder, Maurizio Arico, Lorenzo Moretta, Jan-Inge Henter, Stephan Ehl
Journal: Blood
Blood (2012) 119 (12): 2754–2763.
https://doi.org/10.1182/blood-2011-08-374199
Published: 2012
Includes: Supplemental data
Journal Articles

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome

Birthe Jessen, Andrea Maul-Pavicic, Heike Ufheil, Thomas Vraetz, Anselm Enders, Kai Lehmberg, Alfred Längler, Ute Gross-Wieltsch, Ali Bay, Zuhre Kaya, Yenan T. Bryceson, Ewa Koscielniak, Sherif Badawy, Graham Davies, Markus Hufnagel, Annette Schmitt-Graeff, Peter Aichele, Udo zur Stadt, Klaus Schwarz, Stephan Ehl
Journal: Blood
Blood (2011) 118 (17): 4620–4629.
https://doi.org/10.1182/blood-2011-05-356113
Published: 2011
Includes: Supplemental data
Journal Articles

Drug Resistance and In Vitro Selection of Human Hematopoietic Cells Transduced with Cytidine Deaminase.

Michael Flasshove, MD, Ina Rattmann, Kai Lehmberg, Walter Bardenheuer, PhD, Ursula R. Sorg, PhD, Siegfried Seeber, MD, Thomas Moritz, MD
Journal: Blood
Blood (2004) 104 (11): 5270.
https://doi.org/10.1182/blood.V104.11.5270.5270
Published: 2004